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#81731 - 03/02/04 10:13 PM Vicodin - Hydrocodone Bitartrate and Acetaminophen ****
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Hydrocodone Bitartrate and Acetaminophen

(Most common brand names are: Vicodin, Lortab, and Lorcet. Other brand names are: Anexsia, Azdone, Bancap HC, Ceta-Plus, Co-Gesic, Damason-P, Duocet, Dolacet, Hydrocet, Hy-Phen, Margesic H, Medipain 5, Lorcet HD, Lorcet Plus, Lortab Elixir, Panacet, Stagesic, T- Gesic, Vicodin HP, Zydone).

Health Care Professional Version

Cynthia Kreutzer RN & Jo Eland PhD RN
Every attempt has been made to insure the accuracy of this material, however, medical science is constantly changing. If the information on this page differs from what you have been told by a nurse, pharmacist or physician, consult the person who told you differently or the manufacturer.


--------------------------------------------------------------------------------

Classification: Narcotic Analgesic with Acetaminophen

Use: Used as short-term treatment to relieve moderate to severe pain; also, used as an antitussive. It is a prescription drug and can be addictive due to the narcotic component.

Usual dose: Vicodin 5mg/500mg tablet 1-2 every 4-6 hours not to exceed 8 in 24 hours. Vicodin ES 7.5mg/750mg tablet 1-2 every 4-6 hours not to exceed 5 in 24 hours.

Pediatrics: PO 0.15 mg/kg/dose q 6 hours

Dosages vary according to brand names.

Lortab Elixer: 2.5/167 mg 15 ml Lortab: 2.5/500 mg tablet
Anexsia: 5/500 mg tablet mg Lortab: 5/500 mg tablet
Panacet: 5/500 mg tablet Lorcet: 5/500 mg tablet
Stagesic 5/500 capsule Bancap HC: 5/500 mg capsule
T-Gesic: 5/500 mg capsule Ceta-Plus: 5/500 mg capsule
Zydone: 5/500 mg capsule Co-gesic: 5/500 mg capsule
Azdone: 5/500 mg tablet Duocet: 5/500 mg capsule
Damason-P: 5/500 mg tablet Dolacet: 5/500 mg capsule
Medipain 5: 5/500 mg tablet Hydrocet: 5/500 mg capsule
Lorcet HD: 5/500 mg capsule Hy-Phen: 5/500 mg tablet
Margesic H: 5/500 mg capsule
Lortab: 7.5/500 mg tablet Anexsia: 7.5/650 mg tablet
Lorcet Plus: 7.5/ 650 mg tablet Vicodin ES: 7.5/750 mg tablet
Lortab: 10/500 mg tablet Lorcet: 10/650 mg tablet
Anexsia: 10/660 mg tablet Vicodin HP: 10/660 mg tablet
Route: Oral

Action: Hydrocodone is similar to codeine in its action, working on the central nervous system and smooth muscle. It is believed to relate to opiate receptors in the central nervous system. Acetaminophen works in the periphery as an analgesic but also has antipyretic effects. It is absorbed rapidly in the GI tract and is distributed to most tissue areas in the body. Acetaminophen inhibits the production of prostaglandin which then may cause irritation to the stomach.

Onset: approximately 30 minutes

Peak: 1.3 + 0.3 hours

Steady State: After repeated doses at 4-6 hour intervals, a steady state is reached after the 5th dose (20 — 30 hours).

Metabolism: Hydrocodone is metabolized in the liver and excreted by the kidney.

Half Life: Hydrocodone 3.8 + 0.3 hours. Acetaminophen 1.25-3 hours

Contraindications: Hypersensitivity to hydrocodone or acetaminophen.

Warning: Use of Vicodin with MAO inhibitors or tricyclic antidepressants may increase the effect of either the antidepressant or the hydrocodone. Using Vicodin with other narcotics, antihistamines, anti-psychotic, anti-anxiety, other central nervous system (CNS) depressants, or alcohol may increase CNS depression.

Precautions: Use with caution in patients with a head injury. Narcotics tend to increase intracranial pressure. Narcotics such as Vicodin may interfere with the diagnosis and treatment of patients with abdominal conditions. Use with caution in patients with liver, kidney disorder, underactive thyroid gland, Addison’s disease, enlarged prostate or urethral stricture.The effects of Vicodin in pregnancy have not been established. Pregnant women must consult their physician before taking Vicodin. Drug dependence occurs in newborns when the mother has been taking this drug prior to delivery. If taken shortly before delivery, it may cause respiratory depression in the infant. Acetaminophen is present in breast milk and Hydrocodone may be present in breast milk; therefore, it is not advised to be administered to nursing mothers.

Drug Interactions: Use caution in combination with following drugs:

Sedatives: Halcion, Restoril
Tranquilizers: Thorazine, Haldol
Antidepressants: Elavil, Nardil,Tofranol
Carbamazepine: Tegretol
Other analgesics: Demerol
Antihistamine: Tavist
Anti-anxiety: Valium, Librium
Anti-spasmodic: Cogentin
Ceiling: Because of the acetaminophen content, there is a ceiling. Doses of acetaminophen should not exceed 4000 mg in 24 hours.

Administration: Do not administer to pediatric patients. Use with caution in elderly patients or those with impaired renal or hepatic function. Use with caution during pregnancy or nursing mothers.

Effectiveness: Pain level will decrease and patient will report less pain.

Side Effects: Most common from Vicodin: dizziness, sedation, nausea, vomiting, constipation. Less common: Mood changes, mental cloudiness, anxiety, lethargy, urine retention, ureteral spasm, lightheadedness, irregular breathing, respiratory depression, pruritus, skin rash, impaired mental and physical performance. Side effects of acetaminophen are allergic reaction, rash, thrombocytopenia (decreased number of platelets), agranulocytosis (decreased number of agranular white blood cells).

Overdose: Symptoms of overdose include: blood disorders, cyanotic skin color, cold clammy skin, increasing sedation progressing to unresponsiveness, diaphoresis, irregular heartbeat, decreased heart rate, weakness, low blood pressure, nausea, vomiting, irregular or depressed respirations. Treatment is administration of Nalaxone.

Storage: Store at room temperature away from sunlight and moisture.
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#81732 - 03/08/05 04:05 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
Nunez108 Offline
Newbie


Registered: 03/01/05
Posts: 29
Can you order this med online with no prescription
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#81733 - 03/10/05 01:08 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
dsmmcm Offline
Veteran


Registered: 11/08/03
Posts: 694
Loc: southwest US
Not totally legally, but you can get it from No Records OP's. A legal gray area to be sure.
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#81734 - 09/06/05 06:11 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
Eddie1907 Offline
Stranger


Registered: 08/03/05
Posts: 10
This can be purchased from www.onlinesolutions4u.com without a prescription.
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#81735 - 09/13/05 12:40 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
therodeoclown Offline
Stranger


Registered: 06/05/05
Posts: 13
Loc: United States
Bull Sh.... Eddie your full of [censored]
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#81736 - 09/14/06 08:30 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
raleighdr12 Offline
Banned


Registered: 11/11/04
Posts: 17
Loc: North Carolina
I just received my prescription of generic Hydro 10-500 w/APAP from an ROP and it turned out to be the Qualitest brand. After taking Watson 10-500's, I noticed a HUGE difference with the Qualitest brand.

Aside from providing me with very little pain relief for my lower back area (I now have to take more than double the usual dose to get the same effect the Watson's had), the Qualitest hydrocodone upsets my stomach AND makes me feel extremely nauseous and sleepy, which is causing problems for me with my job.

Has anyone out there had a similar experience when switching from one generic brand of Hydro w/APAP to another? If so please let me know which brands you switched from/to and the main differences.

Thanks!

Diane

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#81737 - 09/16/06 06:16 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
bettysherilee Offline
Stranger


Registered: 08/27/06
Posts: 1
Does anyone know what hydrocodone shows as in a urine drug screen? i have a preemployment ua, and am on rx hydros?
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#81738 - 09/16/06 06:54 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
2thClnr Offline
Newbie


Registered: 05/15/06
Posts: 47
Loc: Not in OZ
Hydrocodone shows up in the pre-screening as an opiate as do all the other opiate narcotice pain relievers. If the testing site wants to find out exactly what it is they have to do a more detailed test.

If you aren't worried about the UA, and they ask you to report any meds that might show up....it is important to do so. As long as you report it and have a legit reason for taking it, they cannot say they won't hire you.

Good luck

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#81739 - 09/16/06 07:06 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
Julz Offline
Board Addict


Registered: 11/17/03
Posts: 383
Loc: NJ Shore
Quote:

Hydrocodone shows up in the pre-screening as an opiate as do all the other opiate narcotice pain relievers. If the testing site wants to find out exactly what it is they have to do a more detailed test.




This is 100% TRUE~ Hydrocodone DOES show up as an opiate. No matter how many mgs you take daily, it will be out of your system in 48 hours.

Peace,

Julz
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#81740 - 09/16/06 08:28 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
MrCharlie Offline
Banned: multiple account to create trouble and shill.Same as CosmiCharlie and others


Registered: 01/22/06
Posts: 320
Loc: Joliet
Quote:

Quote:

Hydrocodone shows up in the pre-screening as an opiate as do all the other opiate narcotice pain relievers. If the testing site wants to find out exactly what it is they have to do a more detailed test.




This is 100% TRUE~ Hydrocodone DOES show up as an opiate. No matter how many mgs you take daily, it will be out of your system in 48 hours.

Peace,

Julz




100% FALSE. Sorry but I have to disagree. A five panel DT is only looking for codeine/morphine based opiates or opiates that contain or are metabolized into 1 of those compounds. I have passed several 5-panel DT's while taking large doses of hydro, because it's not metabolized into codeine or morphine. It's my understanding that even Oxy won't show on a standard NIDA-5 Gas Chromatography/Mass Spectromety test.

I'm sure many folks are going to disagree and give personal examples of their own failures. My info is from Erowid and my experiences are personal and true. Hydro will not show up on your run of the mill pre-employment screening, unless the company specifically requests that it is added to the list.

Report the med, if you want to, I don't. If you do they may not hire you, even though it's illegal, because you are "damaged goods". Also, when you get ins. they may consider your pain to be pre-exsisting and not cover it. Unless you're applying for a Gov., transportation or other vital to the economy or security, of the country position, they aren't going to be looking for Hydro. Like I said report it if you want. I'd wait until it comes back positive, it shouldn't, and then and only then give up the info on taking pain meds. IMHO.

BTW AAA...- nevermind looks like someone already took care of you.


Edited by MrCharlie (09/17/06 03:41 AM)
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#81741 - 09/17/06 01:24 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
VAequestrian Offline
Banned: same as ArmaniBoy, painstruck2, UKmigraine


Registered: 03/28/06
Posts: 1416
Loc: Between a rock and a hard plac...
Well here is the first personal experience lol...Im not agreeing or disagreeing with anyone...I PERSONALY have no clue what does or doesnt show up....however..ive never had a problem with it on pre-employment screening,and i've had alot of them and have been on multiple narcotics over the past 4 yrs. Including Hydro, Xanax, and Oxycodone.
BUT my sister had probation in which she had to do urine test and it DID show up for her...diffrent types of test? I dunno..im not a dr or scientist...but theres my story
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#81742 - 09/17/06 02:22 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
MrCharlie Offline
Banned: multiple account to create trouble and shill.Same as CosmiCharlie and others


Registered: 01/22/06
Posts: 320
Loc: Joliet
I think the test PO's give is much more broad, in what it looks for. They need to seperate heroin(contains codeine and morphine I believe) and hydro. I have no experience with the parole system so this is a total guess.
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#81743 - 09/17/06 06:15 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
DonBarba Online   content
Pooh-Bah


Registered: 04/02/04
Posts: 1266
I think you're right

http://www.erowid.org/pharms/hydrocodone/hydrocodone_testing.shtml

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#81744 - 09/17/06 11:03 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
MrCharlie Offline
Banned: multiple account to create trouble and shill.Same as CosmiCharlie and others


Registered: 01/22/06
Posts: 320
Loc: Joliet
Thank you for posting a link to Erowid, so folks can see we're not full of it, LOL. Erowid hasn't let me down yet and I believe most of what I read on their website. It is an excellent source of answers, for most of us, if we know about it. The only real problem with hydro and drug testing is, how do you find out the type of test beforehand? DOT testing will look for hydro but I think most urinalysis testing is a 5-panel GC/MS.

Anyone else have any feelings as to whether or not to mention hydro use before you take a pre-employment or random drug test?
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#81745 - 09/17/06 11:28 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
tbandit Offline
Stranger


Registered: 04/30/04
Posts: 24
For what it's worth, my opinion is don't report it. If it does turn up, you should still be okay if you can produce a valid rx. If you report it beforehand, as someone else pointed out, you're admitting up-front to a chronic medical condition, which employers WILL take note of. It's very simple for them to manufacture some other reason for choosing another applicant.
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#81746 - 09/17/06 03:00 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
2thClnr Offline
Newbie


Registered: 05/15/06
Posts: 47
Loc: Not in OZ
OK, I guess I don't know everything (LOL) Sorry, but I am going by the test that I have to take pretty much on a monthly basis because of a situation I got myself into. They "pre-screen" for like 5 groups of drugs and also alcohol. Then if they want to be specific they test it more. That's why they fill 2 vials with the urine I suppose

Get this,,,,,,I had something to drink on a Friday,,,,was tested on the next Wed.( 5 days) later so I thought I was okay.....NOT !!!!!! There is an enzyme produced by the liver that will show up on a urinalysis that showed that I indeed had had some alcohol recently. I was floored!
But, my bad. That's why I was being tested in the first place. OOPS !!! Anyhoo, I've been sober almost 1 year now so that's no longer an issue (well, for today anyway!)

Sorry if I mislead anyone. As I said, I was going by the test I'm given. And to think, I get to do this for 2 more years. Call an 800 # every morning to see if I've been "selected" for testing. At 65 dollars a pop, sometimes twice a month. SUCKS. You play, you pay.

Bye now.

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#81747 - 09/17/06 04:13 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
littlered363 Offline
Banned. Shill and scammer. Con artist
Pooh-Bah


Registered: 03/16/06
Posts: 1113
Loc: somewhere over the rainbow
When My brother gets his monthly urine test from his PO, he said that hydro has never showed up. Although he takes his script with him every time just incase. But it has came up clean every time.
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#81748 - 09/17/06 05:39 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
MrCharlie Offline
Banned: multiple account to create trouble and shill.Same as CosmiCharlie and others


Registered: 01/22/06
Posts: 320
Loc: Joliet
That's odd, but like I said some people have failed 5-panel tests because of hydro. I think a persons health, diet and lifestyle play an important role in passing or failing, also. I passed a DT before, back when I smoked pot everyday. I also, ate a protien rich diet, exercised, took supplements and drank tons of water and green tea. Either the lab botched the test or other factors contributed to my passing the test. Then again maybe it was just luck? Who knows? I'm certainly not an expert, although I like to play one.
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#81749 - 10/15/06 11:17 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
Mark4265 Offline
Newbie


Registered: 02/05/06
Posts: 30
I am enquiring if any one is aware of the difference in quality in Hydro 10/650 and vicodin10/660. The service I use has a difference in price. I take the Watson 10/650 and dont want to sacrifice quality. Thank you for your time and consideration.

Mark

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#81750 - 10/16/06 04:54 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
tem33 Offline
Threadhead


Registered: 01/08/03
Posts: 890
Loc: Bullet with Butterfly Wings
Here is the difference: Lorcet 10/650 -- 10mg hydro/650 apap
Vicodin HP -- 10mg hydro/750 apap
It only boils down to 100mg difference in apap.

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#81751 - 10/16/06 11:20 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
Mark4265 Offline
Newbie


Registered: 02/05/06
Posts: 30
To tem33- Thank you for your response. I appreciate the information. I was asking about the 10/650 vs Vic. 10/660, does that mean that the 10/660 is actually 10/750. Also, in your experience, is their a difference in quality? The reason I ask is that the blue 10/500 tend to make me ill. I thank you again for your time and information.

MARK

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#81752 - 10/17/06 02:14 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
dexter00 Offline
Veteran


Registered: 02/04/04
Posts: 514
I too have had problems with Qualtest making me sick.......ended up changing OP's because they could not guarentee me that I would not get them at times when supplies are low. They made me very ill almost like having the Flu.
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#81753 - 10/18/06 02:17 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
tem33 Offline
Threadhead


Registered: 01/08/03
Posts: 890
Loc: Bullet with Butterfly Wings
I don't think the extra 100mg apap is what is making you sick, it is probably something in the generic (filler), or the biodynamnics of the hydro for certain manufactors. Hydro naturally stimulates the vomitting center in the brain.
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#81754 - 11/09/06 05:03 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
MichelleH Offline
Member


Registered: 10/30/06
Posts: 121
Cool pic!
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#81755 - 11/09/06 05:40 AM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
prisjean Offline
Veteran


Registered: 05/12/05
Posts: 709
MrCharlie....I totally agree with your post, years ago while job hunting...I was hired and under went prescreening for that position. I was totally honest and up front about being on the hydro., but nothing showed up! I passed with flying colors. I could never figure that out until I read your post and now understand why. They were probably looking for harder drugs in my system.
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#81756 - 11/13/06 09:38 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
timetells Offline
Stranger


Registered: 11/07/06
Posts: 2
After my surgery I was taking 10/500 and they worked great. I think they were what's called Mallies. Recently I'm taking 10/325 Watson and they seem different. They don't seem as strong and they make me sleepy whereas the Mallies didn't.

Anyone have this experience or similar?

Also, do you think name brands seem to be better than generics?

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#81757 - 11/13/06 09:42 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
faerie Offline
GRAND Pooh-Bah


Registered: 03/28/05
Posts: 5936
ok mallies are one version of that pill, for many of us they are really hard on the stomach...they are a generic brand called mallinkrodt (sp?) anyway the higher dose of tylenol does make the med a little stronger/more effective but many of us have to be concerned about tylenol amounts so for us we like the 325s best. since you can't safely go above 4000 mgs of tylenol a day (and i've even heard 3000 for long term use) without really risking your liver, it's a way to keep that risk minimized without majorly affecting the pain control. as far as the sleepiness goes that shouldn't have changed with only the doseage change unless you're body became more tolerant, which is my guess of what is going on. good luck~faerie (oh, and my first choice in hydro is the generic watson, my second choice is zydone brand name (they are 10/400), my third choice is name brand)
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#81758 - 11/13/06 10:00 PM Re: Vicodin - Hydrocodone Bitartrate and Acetaminophen
artstangl3 Offline
Member


Registered: 11/01/04
Posts: 173
HI Faerie!

I just wanted to say hello and to see how you are doing.

Artstangl3
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