VIP Area
Join our VIP Program
- Free Board - Who's Online
Posting Rules

http://www.southwestmedicalgroup.com - $25 Off Consultation Fee for VIP's

Pharmacy List: US List · Comprehensive OCS List · International List · Canadian List · Black List · Drug List · Compare Prices
Page 1 of 2 12>
Topic Options
Rate This Topic
#748334 - 08/17/08 05:49 AM Amitriptyline question
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
Can anyone tell me if the next day hangover effect of amitriptyline go away after a while?

My pain management doctor put me on these (25mg) to help sleep through the night. The first time I took one I had to miss work the following day because I was so groggy. I told my doctor about it and he suggested cutting them in quarters, which I did, but I am still very much "not normal" after 10 hours. I am also on trazadone (50-100mg). He is not willing to give me any long lasting pain meds, so his solution is to have me sleep through the pain.

Thanks for any input
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748392 - 08/17/08 08:19 AM Re: Amitriptyline question [Re: stevevi]
pillar Offline
GRAND Pooh-Bah


Registered: 11/07/06
Posts: 1944
Loc: The Doors of Perception
From amitriptyline, yes. Trazadone and amitriptyline will take a long time to develop that kind of tolerance. I'm shocked you're being prescribed both. I've taken them separately but never together. How long have you been on the Traz. and amitrip.? If you've been on the Trazadone longer you may adjust to the amitriptyline sooner since 100mg of Traz. is stronger than 25mg of amitriptyline.
_________________________
"God deliver us from such criminal imbecility."

Top
#748449 - 08/17/08 10:09 AM Re: Amitriptyline question [Re: pillar]
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
I've been on the Trazadone a long time (6-7 yrs), The amitriptyline is new. I've taken the whole 25 mg once, to a disastrous hangover, then tried a half pill, still with hangover, I tried a quarter last night, and while not as hungover, I am very sluggish and glad I didn't need to go to work this morning.

When I started the trazadone, Their were side effects, but after a few days the side effects wore off. I'm wondering if with the amitriptyline if I struggle through a few days if I can expect that hangover feeling to subside. They do solve the sleeping through the pain issue, but I also need to be alert for a 5AM job.
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748459 - 08/17/08 10:35 AM Re: Amitriptyline question [Re: stevevi]
kskex5 Offline
Old Hand


Registered: 11/24/04
Posts: 414
I take the 10mg amitryptyline and the hangover effect lasted about a month. It does help damper the pain receptors.
Top
#748488 - 08/17/08 11:06 AM Re: Amitriptyline question [Re: kskex5]
skh1825 Offline
Journeyman


Registered: 12/02/07
Posts: 91
Hi,

I used to take one-fourth of a 25 mg Ami tablet each night at bedtime but never really got used to it and would feel really hung over all the next day. It did, however work very well for my tinnitus/hyperacusis/headache pain.

Have you tried nortriptyline (I think the generic is pamelor)? It is a milder version of Amitriptyline and works pretty well but you're not as hung over the next day.

Top
#748490 - 08/17/08 11:08 AM Re: Amitriptyline question [Re: kskex5]
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
 Originally Posted By: kskex5
I take the 10mg amitryptyline and the hangover effect lasted about a month. It does help damper the pain receptors.


Well, thanks for that ray of hope. I guess, for now, I will have to restrict myself to the weekends, as I would be a disaster at work with the hangover that it causes at this point.
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748497 - 08/17/08 11:12 AM Re: Amitriptyline question [Re: skh1825]
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
SKH -
No, I've not tried any other meds of this type. My doctor is seemingly willing to write for anything as long as it is not a long lasting pain med, so I'll be talking to him probably on Tuesday to see what is next. I am so tired of 3 -4 hours sleep every night.
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748514 - 08/17/08 11:52 AM Re: Amitriptyline question [Re: stevevi]
Stacy Offline

GRAND Pooh-Bah


Registered: 11/15/02
Posts: 2010
Loc: USA
I believe it was amitryptyline I took for HA prevention. If amitryptyline is generic Elavil, then I took that. Yes, the drugged, sleepy feeling does stop, but in my experience about the time it stopped, it was time to up the dose, so I never really got over it. The dosage depends on the reason they are giving it to you.

As far as helping with pain, I am only aware that it actually helps with nerve pain and it really does help. The problem is you have to build up to a very high dose for it to help with that.

I stopped taking it because it made me more drugged than narcotic pain meds and it also made me gain LOTS of weight. At the time I took it (years ago) I did some research and it had been used in a trial for anorexia patients. They weren't eating, yet they were gaining weight. I stopped smoking when I started the Elavil and so I was very, very watchful of what I was eating and I was very much counting calories. I was eating about 800 calories a day and still gaining weight. It did help with HA prevention, but the drugged, sleepy feelings (I HAD to take a nap everyday) and the weight gain made me stop it and try something else.

On a side note stevevi, why is your doc so against long acting meds?

edited to add: I also took Trazadone years later for HA prevention and while that made me sleepy, it wasn't the same drugged, not just sleepy but so physically tired it was hard to move my body parts, sleepy that Elavil caused. I got used to the Trazadone a lot quicker than the Elavil.


Edited by Stacy (08/17/08 11:57 AM)

Top
#748516 - 08/17/08 11:55 AM Re: Amitriptyline question [Re: stevevi]
Stacy Offline

GRAND Pooh-Bah


Registered: 11/15/02
Posts: 2010
Loc: USA
 Originally Posted By: stevevi
 Originally Posted By: kskex5
I take the 10mg amitryptyline and the hangover effect lasted about a month. It does help damper the pain receptors.


Well, thanks for that ray of hope. I guess, for now, I will have to restrict myself to the weekends, as I would be a disaster at work with the hangover that it causes at this point.


One more thing, as I said I am only aware of it helping with the nerve pain, but I haven't done a lot of research on this drug in quite some time; but it was not something to take "when needed" at all. It needs to consistantly be in your system to work to relieve the pain, prevent HA, help with depression, etc.

Is your pain nerve pain, if you don't mind me asking?

Top
#748549 - 08/17/08 01:01 PM Re: Amitriptyline question [Re: Stacy]
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
I'm not sure Stacy, if he "is so against" long lasting pain meds, or just wants to burn out every other option first.

To answer your other question, yes it is nerve pain. I've had 2 surgeries L5-S1 2 1/2 years ago, L4-L5 last year and am currently doing yet another round of epidural shots before we try to figure out what is next. I really don't want any more surgeries if I can help it. Both of mine were successful to a degree, but the damage to the nerves was done before they were willing to do my first surgery. I still have partial numbness in my left foot from my first surgery and my leg ALWAYS hurts.
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748557 - 08/17/08 01:17 PM Re: Amitriptyline question [Re: stevevi]
nephro Offline
GRAND Pooh-Bah


Registered: 09/04/06
Posts: 8570
Loc: UK, despite the rumours
I think being on two antidepressants is somewhat insane, unless the doctor is a consultant in a related field. Especially since they both fall under the same group, roughly.

You can take low doses for nerve pain, 10mg-25mg at night, but gabapentin and pregabalin are also options, and as the poster above says, nortriptyline.

If you break the amitriptyline tablets, you must be very careful to make sure the fractions get all the way down your throat; the pain if one gets stuck is considerable.

Top
#748565 - 08/17/08 01:33 PM Re: Amitriptyline question [Re: stevevi]
Stacy Offline

GRAND Pooh-Bah


Registered: 11/15/02
Posts: 2010
Loc: USA
 Originally Posted By: stevevi
I'm not sure Stacy, if he "is so against" long lasting pain meds, or just wants to burn out every other option first.

To answer your other question, yes it is nerve pain. I've had 2 surgeries L5-S1 2 1/2 years ago, L4-L5 last year and am currently doing yet another round of epidural shots before we try to figure out what is next. I really don't want any more surgeries if I can help it. Both of mine were successful to a degree, but the damage to the nerves was done before they were willing to do my first surgery. I still have partial numbness in my left foot from my first surgery and my leg ALWAYS hurts.


Ah...then I really don't think taking them on the weekends is going to help. Granted, I'm not a doc or a pharm, but IIRC when my aunt took them for nerve pain her dosage ended up being in the hundreds of mgs, don't remember if it was the 1,2 or 3 hundreds.

Just did a quick search and found a site saying it would be between 75mg-150mg you would definately have to build up to even that lowest dose, you couldn't start with 75mg and function at all.

Here is some other info I found on it, I don't know how correct it is, but that article said two weeks was generally the quickest you would start to notice the pain releif benefit of it.

I did a google search with the terms: Amitriptyline for pain build up and there was a lot more info.

As far as a doc not prescribing long acting meds, you can't bet your bottom dollar if it was their pain, their wife, their son/daughter they would be on long acting pain meds. The long acting meds are better for a person, not all the APAP or Ibuprophen and the person feels much better. They sleep through the night most of the time, they don't have at least an hour several times a day where the short acting med gets to the end and the next pill kicks in.

Hope it all works out for you.

Top
#748611 - 08/17/08 02:30 PM Re: Amitriptyline question [Re: Stacy]
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
Thanks for all the answers and input. I am going to put the pills away for an emergency (when I haven't slept for 4-5 days). And stick with the trazadone with an occasional 5mg ambien. I have to talk to the doctor this week anyway, so I'll see what else he has up his sleeve. All in all, going through this for many years with a few different doctors, I am happy with him as he has always been willing to "try something else".

I'll probably be back with questions about some other drug i never heard about in a week or two.

Thanks again.
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748614 - 08/17/08 02:31 PM Re: Amitriptyline question [Re: nephro]
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
Nephro,
You've gotten cuter than I remember you being.
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748626 - 08/17/08 02:57 PM Re: Amitriptyline question [Re: stevevi]
nephro Offline
GRAND Pooh-Bah


Registered: 09/04/06
Posts: 8570
Loc: UK, despite the rumours
Oh I've always been rather pretty.
Top
#748648 - 08/17/08 03:50 PM Re: Amitriptyline question [Re: nephro]
Swirl Offline
Veteran


Registered: 04/17/04
Posts: 507
Loc: Over the rainbow
Wow, it amazes me that it makes people sleepy. It's one of the first meds I was ever prescribed. I was taking 75mg a day and an insomniac. My mom has taken it for 25+ years and they don't even think of taking her off due to the longevity of her taking the med. At this point, I don't recall what she takes it for. Sleep or pain issues. Initially, I know she was prescribed it for depression. Even though she will argue that today.
_________________________
-The one thing that remains the same is change.-

Top
#748733 - 08/17/08 06:54 PM Re: Amitriptyline question [Re: Swirl]
skh1825 Offline
Journeyman


Registered: 12/02/07
Posts: 91
Stevevi,

I re-read your original comment. If you just need something to help sleep thru the night, have you ever tried ambien? Ambien reminds me a lot of amitriptyline in that it helps you sleep real well except that ambien wears off by the time you wake up (8 hours later or so) and it also helps with headaches and other pain during that time and a little into the next day, except no grogginess the next day.

>>> My pain management doctor put me on these (25mg) to help sleep through the night.

Top
#748858 - 08/18/08 02:56 AM Re: Amitriptyline question [Re: skh1825]
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
 Originally Posted By: skh1825
Stevevi,

I re-read your original comment. If you just need something to help sleep thru the night, have you ever tried ambien? Ambien reminds me a lot of amitriptyline in that it helps you sleep real well except that ambien wears off by the time you wake up (8 hours later or so) and it also helps with headaches and other pain during that time and a little into the next day, except no grogginess the next day.

>>> My pain management doctor put me on these (25mg) to help sleep through the night.


Without retelling the whole story (it is on another thread), suffice to say I've had some bad sleepwalking episodes with Ambien. Even if I didn't, they only keep me asleep for 3-4 hours, and yes I've tried the CR. Except for Lunesta (which people have told me is weaker than Ambien), I think I've tried every sleep med on the market.
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748884 - 08/18/08 05:52 AM Re: Amitriptyline question [Re: nephro]
daddyd Offline
Old Hand


Registered: 08/01/08
Posts: 460
Loc: UK
 Originally Posted By: nephro
Oh I've always been rather pretty.
:


We might not win that many but we appreciate them more than any other nation!!! loving it!!!

Get in there Nephro!!!
_________________________
You Have Nothing To Fear But Fear Itself..

Top
#748890 - 08/18/08 06:14 AM Re: Amitriptyline question [Re: daddyd]
excdep Offline
Member


Registered: 11/28/07
Posts: 154
I also took Amitriptyline and I know this hangover very well. I took it for 5 or 6 weeks and I always felt more horrible. This hangover-effect could go away after the first 2-3 weeks if you donīt take a higher dose.
Top
#748910 - 08/18/08 07:22 AM Re: Amitriptyline question [Re: Swirl]
stevo1 Online   content
GRAND Pooh-Bah


Registered: 08/08/06
Posts: 1585
Loc: Top of The World!
 Originally Posted By: Swirl
Wow, it amazes me that it makes people sleepy. It's one of the first meds I was ever prescribed. I was taking 75mg a day and an insomniac. My mom has taken it for 25+ years and they don't even think of taking her off due to the longevity of her taking the med. At this point, I don't recall what she takes it for. Sleep or pain issues. Initially, I know she was prescribed it for depression. Even though she will argue that today.


Sleepy...OMG.....One Pill and I am Knocked Out!!.....The Next morning I feel like I have the Biggest Hangover!

If I took 75mg I would be a Zombie, Stumbling around, Drooling...LOL \:o

Top
#748918 - 08/18/08 07:57 AM Re: Amitriptyline question [Re: stevo1]
JokerOwling Offline
Pooh-Bah


Registered: 07/14/07
Posts: 1038
Loc: here at the moment
 Originally Posted By: stevo1
Sleepy...OMG.....One Pill and I am Knocked Out!!.....The Next morning I feel like I have the Biggest Hangover!

DITTO!!
The sedative affect is suppose to go away after a while,but I stopped taking it after a couple of days.

I have a friend who used to take 75mg/day and he said he couldn't feel anything,at all,no sedation,no pain relief and no anti-depressant effect.
_________________________
"A magnesium deficiency may be responsible for more diseases than any other nutrient."-Dr.Norman Shealy,Neurosurgeon&Chronic Pain expert.

Top
#748921 - 08/18/08 08:03 AM Re: Amitriptyline question [Re: JokerOwling]
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
Well, all this confirms my suspicions. This stuff is not for me. Being in a fog is not my consciousness of choice. I guess I will move on to the next step of having my doctor find something that will help me "sleep through the pain".
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748934 - 08/18/08 08:18 AM Re: Amitriptyline question [Re: stevevi]
JokerOwling Offline
Pooh-Bah


Registered: 07/14/07
Posts: 1038
Loc: here at the moment
I should have added that I know a few other people who have tried it.They all stopped after a few weeks because of the fog/hangover feeling.It made them want to sleep all the time.

It's great if your trying to stop other meds or MJ or something.I keep a couple of tabs for an emergency,but haven't had the courage to take them in over two years.
_________________________
"A magnesium deficiency may be responsible for more diseases than any other nutrient."-Dr.Norman Shealy,Neurosurgeon&Chronic Pain expert.

Top
#748938 - 08/18/08 08:22 AM Re: Amitriptyline question [Re: JokerOwling]
stevevi Online   content
Threadhead


Registered: 05/07/08
Posts: 901
Loc: epharmacywatch.com
Well, that shouldn't be a problem, as he wrote the script for 75 x 25 mgs with 3 refills. I guess he was pretty confident they would work.

They will go into the rainy day drawer for when I hopefully get off opiates someday. I know I will want them then.
_________________________
Get your facts first, then you can distort them as you please - M. Twain

Top
#748959 - 08/18/08 08:42 AM Re: Amitriptyline question [Re: JokerOwling]
pillar Offline
GRAND Pooh-Bah


Registered: 11/07/06
Posts: 1944
Loc: The Doors of Perception
 Originally Posted By: JokerOwling
 Originally Posted By: stevo1
Sleepy...OMG.....One Pill and I am Knocked Out!!.....The Next morning I feel like I have the Biggest Hangover!

DITTO!!
The sedative affect is suppose to go away after a while,but I stopped taking it after a couple of days.

I have a friend who used to take 75mg/day and he said he couldn't feel anything,at all,no sedation,no pain relief and no anti-depressant effect.


Word of warning. I was taking 75mg recently and my Dr. helped me wean off of it as it wasn't really working and he said it has "Cardiotoxicity issues" and he no longer feels comfortable putting patients on doses above 10mg.
_________________________
"God deliver us from such criminal imbecility."

Top
#749088 - 08/18/08 12:18 PM Re: Amitriptyline question [Re: pillar]
nephro Offline
GRAND Pooh-Bah


Registered: 09/04/06
Posts: 8570
Loc: UK, despite the rumours
Indeed, amitriptyline is no longer recommended for prescription in the UK. Heart-block and arrythmias may occur, and those with cardiac disease should certainly stay away from the drug (increased risk of sudden death).

It also has a high fatality rating in overdose.

I think these problems are more in relation to antidepressant doses, such as 75-150mg/day, and not so much the low doses just as Pillar says, so it's worth discussing with your doctor.

Some people hardly ever get tolerant to the sedative effect of the drug; it certainly has an advantage over the benzos in this respect.


Edited by nephro (08/18/08 12:19 PM)

Top
#749267 - 08/18/08