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#740666 - 08/02/08 11:14 PM Alprazolam, Clonazepam, or Diazepam ...which do you prefer?
Art_Vandelay Offline
Journeyman


Registered: 07/17/08
Posts: 76
Loc: East Coast, US

Just wanted to know what some of your thoughts were on Alprazolam (Xanax), Clonazepam (Klonopin/Rivitrol), or Diazepam (Valium). Of these Benzos, which do you find more effective for your situation? I was diagnosed w/ GAD (General Anxiety Disorder) 5 years ago and was first prescribed Lorazepam (Ativan). I found this drug absolutely worthless. Having experimented w/ Xanax in the past, I knew it would be a more effective benzo for my situation. I was prescribed 1 mg as needed. After losing my health insurance, like many of you, I began purchasing my meds on the net. I moved up to 4-5 mg of Xanax daily as my tolerance increased. A friend then told me about Valium's longer lasting effects, so I switched from Xanax to Valium and have been kind of back and forth ever since. I have no prior experience with Clonazepam (Klonopin/Rivitrol), but have heard some good things about this benzo, and have an order on its way. I am curious to which Benzos some of you prefer and why you prefer it? How would you compare the three to each other?

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#740669 - 08/02/08 11:23 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you prefer? [Re: Art_Vandelay]
Happy Birthday Code21 Offline
Veteran


Registered: 07/05/07
Posts: 555
Loc: xanadu
Having tried all three, I prefer the Klonopin. Xanax is always a hit or miss with me, it can either make me feel real drowsy and weird, or do nothing at all. I like valium for tension headaches as it helps to ease my neck pain. But the Klonopin is best for my anxiety - it has a nice calming effect and lasts a while. That's just my personal experience - I don't know anything about their chemical properties or what scientifically makes them work better than the other. \:\)
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#740673 - 08/02/08 11:54 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you prefer? [Re: Code21]
pillar Offline
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Registered: 11/07/06
Posts: 1944
Loc: The Doors of Perception
I, too, prefer clonazepam. I have GAD, with a panic disorder, and as long as I take the clonazepam occasionally it manages both for me. Diazepam, lorazepam and alprazolam all make me too tired while the clonazepam doesn't but is very relaxing.
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#740830 - 08/03/08 10:50 AM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: pillar]
LAmike Offline
Banned troiblemaker
Member


Registered: 07/03/08
Posts: 107
If you're taking it daily I'd try klonopin first and then Xanax if it doesn't work you. I prefer Xanax for as needed use. It doesn't sound like Valium works for you.
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#740911 - 08/03/08 02:04 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: Art_Vandelay]
nephro Offline
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Registered: 09/04/06
Posts: 8572
Loc: UK, despite the rumours
 Originally Posted By: Art_Vandelay

A friend then told me about Valium's longer lasting effects, so I switched from Xanax to Valium and have been kind of back and forth ever since.


The trick with diazepam is that it only becomes long-acting when taken for a period of time. When taken just now and then, it isn't much different from lorazepam or alprazolam. This is because it has active metabolites which build up gradually until a steady-state is reached.

If you have general anxiety, I'm unsure why you were prescribed something 'as needed'. I would have thought you would need something pretty much all the time. PRN medication is more for acute anxiety.

Have you considered chlordiazepoxide (Librium)? It is possibly the longest acting benzodiazepine, unless you can get Tranxene-SD in the USA (though it may be indicated for alcohol withdrawal; I'm not sure).

Clonazepam would be OK to try; you've seen for yourself how tolerance rose dramatically with alprazolam. It's not a good drug for constant use, due to its short half-life.

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#740912 - 08/03/08 02:04 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: Code21]
Art_Vandelay Offline
Journeyman


Registered: 07/17/08
Posts: 76
Loc: East Coast, US
 Originally Posted By: missanxious
Having tried all three, I prefer the Klonopin. Xanax is always a hit or miss with me, it can either make me feel real drowsy and weird, or do nothing at all. I like valium for tension headaches as it helps to ease my neck pain. But the Klonopin is best for my anxiety - it has a nice calming effect and lasts a while. That's just my personal experience - I don't know anything about their chemical properties or what scientifically makes them work better than the other. \:\)


Thanks for the info Missanxious! How is the initial "calming effect" compared to that of xanax, which is usually fairly strong very quickly upon dosing? Also, is the Klonopin or Rivitrol better (if you have had these brands of Clonazepam)?

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#741136 - 08/03/08 10:20 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: nephro]
Art_Vandelay Offline
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Registered: 07/17/08
Posts: 76
Loc: East Coast, US
 Originally Posted By: nephro


The trick with diazepam is that it only becomes long-acting when taken for a period of time. When taken just now and then, it isn't much different from lorazepam or alprazolam. This is because it has active metabolites which build up gradually until a steady-state is reached.

If you have general anxiety, I'm unsure why you were prescribed something 'as needed'. I would have thought you would need something pretty much all the time. PRN medication is more for acute anxiety.

Have you considered chlordiazepoxide (Librium)? It is possibly the longest acting benzodiazepine, unless you can get Tranxene-SD in the USA (though it may be indicated for alcohol withdrawal; I'm not sure).

Clonazepam would be OK to try; you've seen for yourself how tolerance rose dramatically with alprazolam. It's not a good drug for constant use, due to its short half-life.


As far as being prescribed xanax "as needed" goes, this is basically just what the CVS label stated on the bottle. I was prescribed 60 1mg/month; which I felt was not enough, even though some would say I was lucky to get that high of a dosage & quantity. All this really led to was a huge dose increase due to tolerance, which led me to begin buying medication off of the net (as well as my loss of health insurance). I have actually tried Librium for about 2 or 3 weeks several years ago, but I don't remember it working that well. I think it reminded me somewhat of valium, and i'm certain it was likely a low dose. I haven't heard of Tranxene-SD. Is this some form of a Benzo? I know Librium is also prescribed for alcohol withdrawal, so you never know what other uses Tranxene could be used for. I'll have to do some research. Thanks for your input.

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#741158 - 08/04/08 12:18 AM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: Art_Vandelay]
Happy Birthday Code21 Offline
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Registered: 07/05/07
Posts: 555
Loc: xanadu
I've only had brand name Klon, generic American clonazepam, and I just ordered some clonotrils. So I'm interested to see how the clonotrils compare.

The klon comes on a lot easier for me than the xanax. The xanax makes me tired if it works at all. The klon is like taking a nice deep breath and relaxing. I wish I could describe it better!
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#741166 - 08/04/08 03:13 AM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: Code21]
nikitaylor Offline
Member


Registered: 05/17/07
Posts: 146
Loc: secret pirate island
i love clonazepam. if you suffer from anxiety, particularily GAD, clonazepam works wonders. the best way i can describe its effects on anxiety symptoms is , "it cures what ails ya!"
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#741168 - 08/04/08 03:45 AM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: Art_Vandelay]
nephro Offline
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Registered: 09/04/06
Posts: 8572
Loc: UK, despite the rumours
 Originally Posted By: Art_Vandelay
 Originally Posted By: nephro


The trick with diazepam is that it only becomes long-acting when taken for a period of time. When taken just now and then, it isn't much different from lorazepam or alprazolam. This is because it has active metabolites which build up gradually until a steady-state is reached.

If you have general anxiety, I'm unsure why you were prescribed something 'as needed'. I would have thought you would need something pretty much all the time. PRN medication is more for acute anxiety.

Have you considered chlordiazepoxide (Librium)? It is possibly the longest acting benzodiazepine, unless you can get Tranxene-SD in the USA (though it may be indicated for alcohol withdrawal; I'm not sure).

Clonazepam would be OK to try; you've seen for yourself how tolerance rose dramatically with alprazolam. It's not a good drug for constant use, due to its short half-life.


As far as being prescribed xanax "as needed" goes, this is basically just what the CVS label stated on the bottle. I was prescribed 60 1mg/month; which I felt was not enough, even though some would say I was lucky to get that high of a dosage & quantity. All this really led to was a huge dose increase due to tolerance, which led me to begin buying medication off of the net (as well as my loss of health insurance). I have actually tried Librium for about 2 or 3 weeks several years ago, but I don't remember it working that well. I think it reminded me somewhat of valium, and i'm certain it was likely a low dose. I haven't heard of Tranxene-SD. Is this some form of a Benzo? I know Librium is also prescribed for alcohol withdrawal, so you never know what other uses Tranxene could be used for. I'll have to do some research. Thanks for your input.



This means you were taking 2mg alprazolam per day, and that if you go by the benzo.org equivalence chart, it would mean you would need 40mg diazepam per day or 100mg chlordiazepoxide per day, and I'd be very surprised if you were prescribed these amounts.

This is another common problem; doctors underestimate the potency of alprazolam, and since tolerance took over pretty quick, there's no wonder the other benzos didn't work for you.

Had you started on a more gentle benzodiazepine in the first place, having no tolerance, your story may well have been a more happy one.

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#741224 - 08/04/08 07:20 AM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: nephro]
gya321 Offline
Journeyman


Registered: 07/22/08
Posts: 59
Thats a good question. Im not sure none of them seem to have any affect unless its alot of milligrams.
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#741260 - 08/04/08 08:41 AM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: gya321]
toseph100 Offline
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Registered: 07/15/07
Posts: 217
If you want to treat a longterm anxiety problem, in my experience, clonazepam is wonderful. I haven't developed a tolerance, take a very small dose, and go about my day. The others make me tired and I'm not looking for a high. I actually can't stand xanax.
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#741332 - 08/04/08 10:57 AM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: toseph100]
daddyd Offline
Old Hand


Registered: 08/01/08
Posts: 460
Loc: UK
Do you need to take clonazepam daily as a preventative, like buspirone? or can it be used as a reliever in the event of a panic attack? Does it leave you feeling not heavy at all, that would be great for work purposes!

Ive suffered periodic panic attacks for years and also dont like the Xanax but have never really had any other option offered to me


Edited by daddyd (08/04/08 10:59 AM)
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#741356 - 08/04/08 11:34 AM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: daddyd]
LAmike Offline
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Member


Registered: 07/03/08
Posts: 107
Any benzo can be taken as needed. Clonazepam takes 1-2 hours to kick in instead of 20 minutes for xanax. That is why it's probably a better maintenance med than it is at stopping panic attacks quickly. I find it to have a much milder feel than xanax and lasts me 12 hours.
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#741360 - 08/04/08 11:43 AM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: nephro]
Art_Vandelay Offline
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Registered: 07/17/08
Posts: 76
Loc: East Coast, US
 Originally Posted By: nephro


This means you were taking 2mg alprazolam per day, and that if you go by the benzo.org equivalence chart, it would mean you would need 40mg diazepam per day or 100mg chlordiazepoxide per day, and I'd be very surprised if you were prescribed these amounts.



I never said I was "prescribed" the diazepam or chlordiazepoxide, only the Xanax. Before the Xanax, I was started on Ativan (which is [censored] if you ask me)! I then went to Xanax 1 mg's. When I began using other benzos, I was medicating, using the internet. I had lost my health insurance and was no longer able to afford my Dr. visits. So, like so many, I began ordering certain benzos off of the net. I did this in hopes that I could find the "right" medication. Yes, I have taken 40 mg of Valium per day for quite a while, but never took 100 mg of Librium, in fact I believe I said it was a very low dose at that...

It seems that many users on here are saying that the Clonazepam works quite well for them, I appreciate all your guy's posts! They have been very informative!

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#741457 - 08/04/08 01:54 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: Art_Vandelay]
nephro Offline
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Registered: 09/04/06
Posts: 8572
Loc: UK, despite the rumours
Sorry, I misread. You tried them but not on prescription. But I am I right in thinking that before you were prescribed the lorazepam you had already experimented with Xanax in the past?
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#741494 - 08/04/08 03:02 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: Art_Vandelay]
NotBillGates Offline
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Registered: 01/15/04
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Chlordiazepoxide never did a thing for me. I thought they were just sugar filled capsules?
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#741592 - 08/04/08 07:03 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: NotBillGates]
nikitaylor Offline
Member


Registered: 05/17/07
Posts: 146
Loc: secret pirate island
i got tdo's xanax 2mg xanax bars and they had a weird effect on me. i ended up taking lots in order to feel relaxed and i had hellish WD's. Valium makes me feel hammered.

i think clonazepam is the best benzo to smooth out your anxiety and go about your day.
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#741599 - 08/04/08 07:21 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: nikitaylor]
nephro Offline
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Registered: 09/04/06
Posts: 8572
Loc: UK, despite the rumours
What dose of Valium makes you feel hammered?
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#741600 - 08/04/08 07:22 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: nephro]
nikitaylor Offline
Member


Registered: 05/17/07
Posts: 146
Loc: secret pirate island
i'm too embarrased to say, lol
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golden living, dreams of visions, mystic crystal revalations, and the mind's true liberation: A-QUAR-I-US!

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#741610 - 08/04/08 07:32 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: nikitaylor]
nephro Offline
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Registered: 09/04/06
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Loc: UK, despite the rumours
Well it doesn't really matter; I was just going to suggest that a lower dose might work well for anxiety. It has a quick onset, so isn't bad for acute anxiety as well as general anxiety.

But if you've found success in clonazepam then fine; just remember it's very potent.

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#741620 - 08/04/08 07:48 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: nephro]
nikitaylor Offline
Member


Registered: 05/17/07
Posts: 146
Loc: secret pirate island
i agree with nephro that clonazepam is very potent. it is a benzo that really should be 'respected'. i found that 1mg twice a day was perfect.
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golden living, dreams of visions, mystic crystal revalations, and the mind's true liberation: A-QUAR-I-US!

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#741635 - 08/04/08 08:22 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: nephro]
Art_Vandelay Offline
Journeyman


Registered: 07/17/08
Posts: 76
Loc: East Coast, US

 Originally Posted By: nephro
Sorry, I misread. You tried them but not on prescription. But I am I right in thinking that before you were prescribed the lorazepam you had already experimented with Xanax in the past?



Seriously? ...not so sure this really matters

Back to topic... I started the thread because I wanted to hear what others thought about the three popular Benzos; Alprazolam, Clonazepam, and Diazepam. -Which they preferred and why?

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#741646 - 08/04/08 08:43 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: nikitaylor]
Art_Vandelay Offline
Journeyman


Registered: 07/17/08
Posts: 76
Loc: East Coast, US
 Originally Posted By: nikitaylor
i got tdo's xanax 2mg xanax bars and they had a weird effect on me. i ended up taking lots in order to feel relaxed and i had hellish WD's. Valium makes me feel hammered.

i think clonazepam is the best benzo to smooth out your anxiety and go about your day.


Ahh yes, the infamous Gador Bars from TODO! I'm sorry they had a wierd effect on you, I can tell you this though; They were some of the most potent Xanax available on the net and did pack quite a punch. To me, thus far, Xanax has proven to have the worst WD's of all Benzos. I'm guessing it's because of its extremely short half-life. I've heard of many Docs weaning people off of Xanax w/ Valium and even Librium. Anyway, interesting how just about everybody is recommending clonazepam! That's great news and thanks for your input Niki! I can't wait for my Rivotrils...

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#741650 - 08/04/08 08:52 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you prefer? [Re: Art_Vandelay]
recruiterlo Offline

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Registered: 05/01/06
Posts: 1226
Loc: here for now
i'm sure cosmo kramer could help you...or larry david.
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#741654 - 08/04/08 09:10 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: recruiterlo]
Art_Vandelay Offline
Journeyman


Registered: 07/17/08
Posts: 76
Loc: East Coast, US
 Originally Posted By: recruiterlo
i'm sure cosmo kramer could help you...or larry david.




Being an architect as well as running Vandelay Industries (a small latex company) in NYC, one has little time to acquire the right chill pills!

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#741657 - 08/04/08 09:18 PM Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref [Re: Art_Vandelay]
recruiterlo Offline

Pooh-Bah


Registered: 05/01/06
Posts: 1226
Loc: here for now
i live right here in nyc and you can acquire whatever you want and whatever time you want.

even designing those buildings -- just put on a hard hat and find a dealer cat. you should know that.....can't get no pity if you live in this city.

just don't end up in benzo hell -- as too many have and it sounds like you're in for a bad time -- hopefully later rather than sooner. but it will happen at the amounts you refer to.

good luck, though.


Edited by recruiterlo (08/04/08 09:25 PM)
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#741723 - 08/05/08 04:23 AM </