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#740666 - 08/02/08 11:14 PM
Alprazolam, Clonazepam, or Diazepam ...which do you prefer?
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Art_Vandelay
Journeyman
Registered: 07/17/08
Posts: 76
Loc: East Coast, US
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Just wanted to know what some of your thoughts were on Alprazolam (Xanax), Clonazepam (Klonopin/Rivitrol), or Diazepam (Valium). Of these Benzos, which do you find more effective for your situation? I was diagnosed w/ GAD (General Anxiety Disorder) 5 years ago and was first prescribed Lorazepam (Ativan). I found this drug absolutely worthless. Having experimented w/ Xanax in the past, I knew it would be a more effective benzo for my situation. I was prescribed 1 mg as needed. After losing my health insurance, like many of you, I began purchasing my meds on the net. I moved up to 4-5 mg of Xanax daily as my tolerance increased. A friend then told me about Valium's longer lasting effects, so I switched from Xanax to Valium and have been kind of back and forth ever since. I have no prior experience with Clonazepam (Klonopin/Rivitrol), but have heard some good things about this benzo, and have an order on its way. I am curious to which Benzos some of you prefer and why you prefer it? How would you compare the three to each other?
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#741136 - 08/03/08 10:20 PM
Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref
[Re: nephro]
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Art_Vandelay
Journeyman
Registered: 07/17/08
Posts: 76
Loc: East Coast, US
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The trick with diazepam is that it only becomes long-acting when taken for a period of time. When taken just now and then, it isn't much different from lorazepam or alprazolam. This is because it has active metabolites which build up gradually until a steady-state is reached.
If you have general anxiety, I'm unsure why you were prescribed something 'as needed'. I would have thought you would need something pretty much all the time. PRN medication is more for acute anxiety.
Have you considered chlordiazepoxide (Librium)? It is possibly the longest acting benzodiazepine, unless you can get Tranxene-SD in the USA (though it may be indicated for alcohol withdrawal; I'm not sure).
Clonazepam would be OK to try; you've seen for yourself how tolerance rose dramatically with alprazolam. It's not a good drug for constant use, due to its short half-life.
As far as being prescribed xanax "as needed" goes, this is basically just what the CVS label stated on the bottle. I was prescribed 60 1mg/month; which I felt was not enough, even though some would say I was lucky to get that high of a dosage & quantity. All this really led to was a huge dose increase due to tolerance, which led me to begin buying medication off of the net (as well as my loss of health insurance). I have actually tried Librium for about 2 or 3 weeks several years ago, but I don't remember it working that well. I think it reminded me somewhat of valium, and i'm certain it was likely a low dose. I haven't heard of Tranxene-SD. Is this some form of a Benzo? I know Librium is also prescribed for alcohol withdrawal, so you never know what other uses Tranxene could be used for. I'll have to do some research. Thanks for your input.
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#741168 - 08/04/08 03:45 AM
Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref
[Re: Art_Vandelay]
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nephro
GRAND Pooh-Bah
Registered: 09/04/06
Posts: 8572
Loc: UK, despite the rumours
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The trick with diazepam is that it only becomes long-acting when taken for a period of time. When taken just now and then, it isn't much different from lorazepam or alprazolam. This is because it has active metabolites which build up gradually until a steady-state is reached.
If you have general anxiety, I'm unsure why you were prescribed something 'as needed'. I would have thought you would need something pretty much all the time. PRN medication is more for acute anxiety.
Have you considered chlordiazepoxide (Librium)? It is possibly the longest acting benzodiazepine, unless you can get Tranxene-SD in the USA (though it may be indicated for alcohol withdrawal; I'm not sure).
Clonazepam would be OK to try; you've seen for yourself how tolerance rose dramatically with alprazolam. It's not a good drug for constant use, due to its short half-life.
As far as being prescribed xanax "as needed" goes, this is basically just what the CVS label stated on the bottle. I was prescribed 60 1mg/month; which I felt was not enough, even though some would say I was lucky to get that high of a dosage & quantity. All this really led to was a huge dose increase due to tolerance, which led me to begin buying medication off of the net (as well as my loss of health insurance). I have actually tried Librium for about 2 or 3 weeks several years ago, but I don't remember it working that well. I think it reminded me somewhat of valium, and i'm certain it was likely a low dose. I haven't heard of Tranxene-SD. Is this some form of a Benzo? I know Librium is also prescribed for alcohol withdrawal, so you never know what other uses Tranxene could be used for. I'll have to do some research. Thanks for your input.
This means you were taking 2mg alprazolam per day, and that if you go by the benzo.org equivalence chart, it would mean you would need 40mg diazepam per day or 100mg chlordiazepoxide per day, and I'd be very surprised if you were prescribed these amounts.
This is another common problem; doctors underestimate the potency of alprazolam, and since tolerance took over pretty quick, there's no wonder the other benzos didn't work for you.
Had you started on a more gentle benzodiazepine in the first place, having no tolerance, your story may well have been a more happy one.
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#741360 - 08/04/08 11:43 AM
Re: Alprazolam, Clonazepam, or Diazepam ...which do you pref
[Re: nephro]
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Art_Vandelay
Journeyman
Registered: 07/17/08
Posts: 76
Loc: East Coast, US
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This means you were taking 2mg alprazolam per day, and that if you go by the benzo.org equivalence chart, it would mean you would need 40mg diazepam per day or 100mg chlordiazepoxide per day, and I'd be very surprised if you were prescribed these amounts.
I never said I was "prescribed" the diazepam or chlordiazepoxide, only the Xanax. Before the Xanax, I was started on Ativan (which is [censored] if you ask me)! I then went to Xanax 1 mg's. When I began using other benzos, I was medicating, using the internet. I had lost my health insurance and was no longer able to afford my Dr. visits. So, like so many, I began ordering certain benzos off of the net. I did this in hopes that I could find the "right" medication. Yes, I have taken 40 mg of Valium per day for quite a while, but never took 100 mg of Librium, in fact I believe I said it was a very low dose at that...
It seems that many users on here are saying that the Clonazepam works quite well for them, I appreciate all your guy's posts! They have been very informative!
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#741723 - 08/05/08 04:23 AM
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