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#916436 - 08/10/09 01:10 AM Codeine vs hydro
a7xjoshr Enthusiast Registered: 06/25/09 Posts: 186 Loc: Bat Country	ok i have recently aquired a couple codeins. this is what they are: Generic Name: Codeine, Acetaminophen Strength: 30 mg, 300 mg Manufacturer: Teva Pharmaceuticals Trade Name: N/A Type: Analgesic Class: RX, CIII Size (mm): 10 X 4 Comment: Imprint 93150 3 thats whats on the pill 93 150 /3 on other side i know this has been asked a million times but whats the difference between these and a 10mg hydro? Edited by a7xjoshr (08/10/09 01:14 AM) _________________________ “He who makes a beast of himself gets rid of the pain of being a man.” Samuel Johnson
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#916472 - 08/10/09 05:47 AM Re: Codeine vs hydro [Re: a7xjoshr]
madkw Enthusiast Registered: 05/27/08 Posts: 259 Loc: some were in the sky	hi hydro 10mg is = more than 60 mg codain or 1mg hydro = 10 codain , more or lesss i think
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#916474 - 08/10/09 06:22 AM Re: Codeine vs hydro [Re: madkw]
a7xjoshr Enthusiast Registered: 06/25/09 Posts: 186 Loc: Bat Country	oh ok yeah cus i took 2 and they dont even give me the reliefe of a 7.f hydro, like not even half, actually i dont think codeien doesn anything for me thats wierd? i think i no the reason tho, if ur taking a certain med it can block the codiend from working i think thats my case, idk _________________________ “He who makes a beast of himself gets rid of the pain of being a man.” Samuel Johnson
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#916584 - 08/10/09 02:03 PM Re: Codeine vs hydro [Re: a7xjoshr]
PoPo GRAND Pooh-Bah Registered: 02/20/04 Posts: 1885	I find that Codeine is nowhere as effective as Hydro. For some reason, I don't handle Codeine very well. It nauseates me and causes much worse constipation than any other pain med I've had. Waste of time, in my book. Of course if it's all I have, I will take them. A little relief is better than none, side effects and all. Sometimes ya gotta do what ya gotta do.
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#916602 - 08/10/09 02:41 PM Re: Codeine vs hydro [Re: a7xjoshr]
nephro GRAND Pooh-Bah Registered: 09/04/06 Posts: 10289 Loc: NOT 40!	Originally Posted By: a7xjoshr oh ok yeah cus i took 2 and they dont even give me the reliefe of a 7.f hydro, like not even half, actually i dont think codeien doesn anything for me thats wierd? i think i no the reason tho, if ur taking a certain med it can block the codiend from working i think thats my case, idk 7.5mg hydrocodone is approx equal to 50mg codeine. But remember that a proportion of Caucasians lack the enzyme required to metabolise codeine into morphine, so for those patients, codeine is less effective or doesn't work at all. If you're desperate, taking 3 pills would keep you under the APAP limit, but you aren't really supposed to take more than 60mg codeine at once. It's up to you, of course; 90mg may provide additional analgesia but you'll also get additional side-effects, and I wouldn't do this 4 times a day. The daily recommended limit of codeine is around 240mg.
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#941929 - 10/10/09 12:55 PM Re: Codeine vs hydro [Re: nephro]
Tall Veteran Registered: 04/23/09 Posts: 550 Loc: Out west	Sorry to bring this old thread up, but, Nephro, "what enzyme do Caucasions lack"? _________________________ Only Fools have no respect for Wisdom...
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#941932 - 10/10/09 12:59 PM Re: Codeine vs hydro [Re: Tall]
wofer Pooh-Bah Registered: 07/11/08 Posts: 1148 Loc: Keeping it Real-Land	Originally Posted By: Tall Sorry to bring this old thread up, but, Nephro, "what enzyme do Caucasions lack"? Oh so many replies to this question but so little time.. LOL. _________________________ "Got to ride this streetcar to the end of the line, and it's a one-way trip, and the last stop is the cemetery" Edward G. Robinson
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#941984 - 10/10/09 03:07 PM Re: Codeine vs hydro [Re: wofer]
BassNbeatz Enthusiast Registered: 08/01/09 Posts: 230	The liver enzyme that a proportion of caucasians lack is CYP2D6. Note, not all caucasians lack this enzyme & its not just white people that lack the enzyme. Codeine prodrug and is a CYP2D6 substrate meaning CYP2D6 is necessary in the conversion of codeine to morphine. Edited by BassNbeatz (10/10/09 03:08 PM)
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#946131 - 10/19/09 09:40 AM Re: Codeine vs hydro [Re: BassNbeatz]
OnlyZ Enthusiast Registered: 05/02/08 Posts: 236	The hydrocodone is a much stronger painkiller.
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#946857 - 10/20/09 06:43 PM Re: Codeine vs hydro [Re: OnlyZ]
artlover Journeyman Registered: 12/04/08 Posts: 82	Hydrocodone is stronger, in the ration mentioned above, but I find that combinations of codeine with other drugs are much more effective for my migraines than hydrodcodone/apap. Due to my migraines, I have an ongoing prescription to fiorinal, which is basically codeine/bulbital/acetomenophen/caffeine, and due to severe pinched nerves in my back I have prescriptions for hydrocodone/apap (vicodin.) At the same efficacy levels of the codeine and the hydrocodone in those drugs, the vicodin is more effective on the back pain and the codeine is more effective in the migraines. fwiw
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#951483 - 10/29/09 05:28 PM Re: Codeine vs hydro [Re: artlover]
mateoh Enthusiast Registered: 11/12/08 Posts: 212 Loc: south, USA	I agree. Codeine only helps me when used in conjunction with something stronger to potentiate it. Is there anything online I can read regarding this enzyme ? _________________________ keep the car running.
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#951491 - 10/29/09 05:38 PM Re: Codeine vs hydro [Re: mateoh]
OnlyZ Enthusiast Registered: 05/02/08 Posts: 236	I've found codeine to be useless for anything more than a minor headache. I'm glad it works for your migraines though.
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#957882 - 11/08/09 01:51 PM Re: Codeine vs hydro [Re: OnlyZ]
artlover Journeyman Registered: 12/04/08 Posts: 82	Originally Posted By: OnlyZ I've found codeine to be useless for anything more than a minor headache. I'm glad it works for your migraines though. I think it is the combination of the codeine plus the sedative and caffeine in Fiorinal that makes it more effective for my migraines than just 10/325 hydrocodone. I will say that neither gives me such a buzz or high that I can really understand recreational use - I get more of a "high" from three cups of coffee than either. Saying that, though, I knew a woman once that was always trying to get me to give her Fiorinals from my script and stole them from her husband's script - she was truly hooked. Which I just don't understand.
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#957900 - 11/08/09 02:17 PM Re: Codeine vs hydro [Re: artlover]
TAZLOVER GRAND Pooh-Bah Registered: 02/07/09 Posts: 2965 Loc: Gonna take a trip with my budd...	Originally Posted By: artlover Hydrocodone is stronger, in the ration mentioned above, but I find that combinations of codeine with other drugs are much more effective for my migraines than hydrodcodone/apap. Due to my migraines, I have an ongoing prescription to fiorinal, which is basically codeine/bulbital/acetomenophen/caffeine, and due to severe pinched nerves in my back I have prescriptions for hydrocodone/apap (vicodin.) At the same efficacy levels of the codeine and the hydrocodone in those drugs, the vicodin is more effective on the back pain and the codeine is more effective in the migraines. fwiw I agree. Codeine is a good thing to use for between your hydro doses. With having the back pain, the hydro's do not last until the next dose. Ia good codeine substitute in between should help until you take your next dose. _________________________ There is nothing more precious than having true friends
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#995356 - 01/22/10 01:34 PM Re: Codeine vs hydro [Re: TAZLOVER]
Shanley Journeyman Registered: 01/22/10 Posts: 51	Codeine is very weak and quite use less for pain other than a mild sore throat. _________________________ I make my reality bigger than their dreams are
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#995379 - 01/22/10 02:19 PM Re: Codeine vs hydro [Re: Shanley]
martind GRAND Pooh-Bah Registered: 05/01/08 Posts: 2729	Originally Posted By: Shanley Codeine is very weak and quite use less for pain other than a mild sore throat. That would be startling news to the healthcare providers all over the world who effectively use codeine every day as a pain control medication. You are familiar with "dose-related" equipotency, aren't you? On a mg/mg basis, codeine is weaker than, say, hydrocodone but a 60mg dose of codeine has been shown to have a pain control effectiveness approximately equal to 10mg of hydrocodone. Appropriate treatment for pain conditions far more serious than a mild sore throat.
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#995385 - 01/22/10 02:44 PM Re: Codeine vs hydro [Re: martind]
edgewise1 Enthusiast Registered: 08/05/05 Posts: 293 Loc: NC	I'm amazed at times how people will make such blanket statements about a drug, without doing any research on it. Just because a person takes a certain drug in a certain dose and it doesn't get them as high as they want, they begin to tell people that the drug is no good. But people will be people, it's just the nature of people!
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#995482 - 01/22/10 08:31 PM Re: Codeine vs hydro [Re: edgewise1]
Shanley Journeyman Registered: 01/22/10 Posts: 51	hmmm i never said to get high...shame on you _________________________ I make my reality bigger than their dreams are
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#995494 - 01/22/10 09:14 PM Re: Codeine vs hydro [Re: Shanley]
Milvus Enthusiast Registered: 09/13/07 Posts: 281 Loc: the depths of East Asia	I've found codeine highly effective in the past for mild-moderate back pain (especially the soluble tablets, which work really fast).
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#995678 - 01/23/10 12:19 PM Re: Codeine vs hydro [Re: Shanley]
martind GRAND Pooh-Bah Registered: 05/01/08 Posts: 2729	Originally Posted By: Shanley hmmm i never said to get high...shame on you No, but you said it was "quite use less (sic) for pain" which is patently untrue. Shame on you.
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#995893 - 01/24/10 04:44 AM Re: Codeine vs hydro [Re: martind]
Shanley Journeyman Registered: 01/22/10 Posts: 51	Originally Posted By: martind Originally Posted By: Shanley hmmm i never said to get high...shame on you No, but you said it was "quite use less (sic) for pain" which is patently untrue. Shame on you. Useless due to the fact you have to take soo much to recieve relief...why not take a stronger opiate and submit your body to less foreign material! Everything you put in your body changes it in one way or another for life! Do some research on this at Ebsco Academic Search Premier...very informative! _________________________ I make my reality bigger than their dreams are
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#995965 - 01/24/10 10:45 AM Re: Codeine vs hydro [Re: Shanley]
martind GRAND Pooh-Bah Registered: 05/01/08 Posts: 2729	Can you direct me to the information in EBSCO that supports your advice that codeine is "quite use less for pain" ?
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#996031 - 01/24/10 03:02 PM Re: Codeine vs hydro [Re: Shanley]
nephro GRAND Pooh-Bah Registered: 09/04/06 Posts: 10289 Loc: NOT 40!	Originally Posted By: Shanley Originally Posted By: martind Originally Posted By: Shanley hmmm i never said to get high...shame on you No, but you said it was "quite use less (sic) for pain" which is patently untrue. Shame on you. Useless due to the fact you have to take soo much to recieve relief...why not take a stronger opiate and submit your body to less foreign material! Everything you put in your body changes it in one way or another for life! Do some research on this at Ebsco Academic Search Premier...very informative! Doctors will prescribe codeine in a 15mg, 30mg or 60mg dose because it is less subject to abuse than a smaller amount of a strong opioid. It also has a ceiling which further prevents serious abuse to some extent. Many patients respond very well to doses of codeine as low as 15mg. How does taking one 15mg dose of codeine change your body for life? I would have thought homeostasis to be the key argument against this rather strange theory.
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#996065 - 01/24/10 05:34 PM Re: Codeine vs hydro [Re: martind]
Shanley Journeyman Registered: 01/22/10 Posts: 51	Originally Posted By: martind Can you direct me to the information in EBSCO that supports your advice that codeine is "quite use less for pain" ? Title: Simultaneous HPLC analysis of pseudophedrine hydrochloride, codeine phosphate, and triprolidine hydrochloride in liquid dosage forms Author(s): Manassra A, Khamis M, El-Dakiky M, et al. Source: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS Volume: 51 Issue: 4 Pages: 991-993 Published: MAR 11 2010 _________________________ I make my reality bigger than their dreams are
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#996066 - 01/24/10 05:35 PM Re: Codeine vs hydro [Re: nephro]
Shanley Journeyman Registered: 01/22/10 Posts: 51	Originally Posted By: nephro Originally Posted By: Shanley Originally Posted By: martind Originally Posted By: Shanley hmmm i never said to get high...shame on you No, but you said it was "quite use less (sic) for pain" which is patently untrue. Shame on you. Useless due to the fact you have to take soo much to recieve relief...why not take a stronger opiate and submit your body to less foreign material! Everything you put in your body changes it in one way or another for life! Do some research on this at Ebsco Academic Search Premier...very informative! Doctors will prescribe codeine in a 15mg, 30mg or 60mg dose because it is less subject to abuse than a smaller amount of a strong opioid. It also has a ceiling which further prevents serious abuse to some extent. Many patients respond very well to doses of codeine as low as 15mg. How does taking one 15mg dose of codeine change your body for life? I would have thought homeostasis to be the key argument against this rather strange theory. The human body is an evolving entity and wether you believe it or not everything we do chemicaly or physically changes it! Day one stuff at Med school. However I do believe they told us this to "scare" us into not abusing...so who knows! _________________________ I make my reality bigger than their dreams are
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#996075 - 01/24/10 06:15 PM Re: Codeine vs hydro [Re: Shanley]
nephro GRAND Pooh-Bah Registered: 09/04/06 Posts: 10289 Loc: NOT 40!	When the brain is developing into adulthood, that's the time when drugs should be used with a view to any permanent change. After that, a single dose of paracetamol, morphine or diazepam will not cause permanent change in the body that is measurable. Homeostasis will return the body to its previous condition in a relatively short space of time. Some drugs that cause physiological damage, such as lethal poisons, will of course cause permanent changes such as cessation of life, but relatively harmless drugs will not.
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#996172 - 01/25/10 12:20 AM Re: Codeine vs hydro [Re: nephro]
Shanley Journeyman Registered: 01/22/10 Posts: 51	greatly put nephro! _________________________ I make my reality bigger than their dreams are
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