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#832805 - 01/21/09 02:33 PM
Re: Valium: I feel wonderful
[Re: ggggg0]
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Banned. Recreational drug use discussions and soliciting
Member
Registered: 09/29/08
Posts: 101
Loc: U.K
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Wish I could feel same - Great its working for you, and I understand the long halflife of diazepam vs xanax could be beneficial when tapering. But I gave up with IOPs for now cos everyones gettin ripped off, siezed etc. Well where I live heroin is the drug of choice and there has been a huge drop in quality and availability of heroin in the UK and as a result many addicts turn to valium as it give a somewhat similar effect. So I got this guy who sells thousands of D-10 Diazepam, so Im told, and my friends mouse has been having horrible withdrawral symptoms from the Diazepam, lies in bed shaking no energy very very depressed. The mouse concerned has also been addicted to opiate type drugs and believes Diazepam is far harder to come off.
_________________________
Life is all about asses-you're either covering it, laughing it off, kicking it,kissing it,busting it,trying to get a piece of it,or behaving like one
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#833054 - 01/22/09 12:17 AM
Re: Valium: I feel wonderful
[Re: dvz]
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GRAND Pooh-Bah
Registered: 09/04/06
Posts: 10286
Loc: NOT 40!
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NO! It is IMPERATIVE that you taper off with the same drug you are trying to taper off of. I can't stress this enough. And taper very, very slowly, don't try and do it in a few days or even a couple of weeks. I recommend a month. Trust me on this. And don't introduce another benzo into your system while you are tapering. Take good care, dvz I agree that you should take it slow; a month is round about the minimum, but trying to do a slow taper with a short-acting drug is very difficult indeed. Taking an extreme case, withdrawing from triazolam using triazolam is not much short of barbaric. The same sort of principle is used with opioids. The crossover to a long-acting drug is almost always needed, but sometimes has to be done dose-by-dose, and not suddenly. It may take a couple of weeks to gradually replace alprazolam with diazepam or chlordiazepoxide, and this also reduces the chances of the replacement drug being underdosed. Any withdrawal effects can be compensated for during the transfer process. There's an example of how to gradually replace a short-acting drug with a long-acting drug here: http://www.benzo.org.uk/manual/bzsched.htm#s1
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#952528 - 10/31/09 11:18 AM
Re: Valium: I feel wonderful
[Re: pharm_cost]
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Member
Registered: 08/23/09
Posts: 116
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I'm kinda afraid to say anything here. I'm new and I don't wanna get jumped all over. First, I want to preface my comments by saying it's only my observations, and I say it realizing almost everyone here has way more experience, and knowledge than I do, about almost every topic on these boards. Ok, so please don't yell at me. I cry easy!
I have seen Librium used for alcohol withdrawl, not long term, maybe a week, not longer than two, and on a tapering schedule. It is also in an irritable bowel preparation that I have a hard time remembering the name of without looking it up (perhaps Librax?)
For benzo withdrawal I have seen phenobarbital used. The way I saw it used was that it was begun when shakes/tremors began, which could vary, because as has been pointed out, the w/d from different benzos varies, I THINK around 50mg (not sure) and then tapered. Probably given every 4-6 hours for the first 24, and then tapered as tolerated, but during the taper, if the shakes seemed bad, the taper would plateau.
Now I have a question. Since Valium is slower acting, and w/d symptoms are more delayed, would people consider it less likely to become addictive, than say Xanax? Or maybe it just sneaks up on you more easily. Just wondering what the more experience/knowlegeable opinions are about this. Thanks!
I hope I didn't butt in where I shouldn't have. Admin, you can delete my post if you think I was outta line.
Edited by NascarGurl (10/31/09 11:21 AM) Edit Reason: typos
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#952848 - 10/31/09 10:03 PM
Re: Valium: I feel wonderful
[Re: NascarGurl]
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GRAND Pooh-Bah
Registered: 09/04/06
Posts: 10286
Loc: NOT 40!
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Diazepam is much easier to withdraw from than alprazolam, lorazepam or oxazepam. This is because, although the parent drug has a fairly usual half-life, the metabolites build up such that they become clinically significant, and quite useful. This means that you can taper off the drug much more easily, since dose reductions don't have an immediate effect. It's not like you suddenly get hit with withdrawal symptoms after a few days; the withdrawal is less severe and less sudden than with the shorter-acting drugs. Because it is produced in 10mg, 5mg and 2mg tablets, it is easier to come off it slowly, and the 2mg tablets are especially useful in this regard. In addition, the highest dose unit (10mg) is a lot more sensible than the highest dose units of alprazolam (2mg, which is stupid), lorazepam (2.5mg, which is stupid) and clonazepam (2mg, which is stupid unless you're using it for epilepsy in the long-term). Therefore, doctors who have no clue will prescribe you 10mg diazepam maximum per dose, thinking it must be similar to the top dose of alprazolam. 2mg alprazolam is considered to be roughly equivalent to 40mg diazepam, and doctors who prescribe 2mg alprazolam per dose are causing terrible suffering for patients when they try to reduce. It is a nonsense product, and the manufacturer knows it. But if patients can't get off it, it's more money for them. Perhaps doctors also prescribe it for greed in this respect, if repeated appointments are used, in addition to being clueless. Diazepam is actually rapid-acting, which makes it just as useful as alprazolam when intended to treat panic. It's the drugs that "switch off" rapidly, such as alprazolam, that are quite evil and brutal to withdraw from, not to mention life-threatening if suddenly stopped.
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#952861 - 10/31/09 10:32 PM
Re: Valium: I feel wonderful
[Re: nephro]
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Member
Registered: 08/23/09
Posts: 116
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It's not like you suddenly get hit with withdrawal symptoms after a few days; the withdrawal is less severe and less sudden than with the shorter-acting drugs.
That's reassuring. This board is a wealth of information. So, I have another question. Can you keep from developing a tolerance to a specific benzo, by alternatiing the benzo you are taking, ie, switch from alprazolam to diazepam? I realize tolerance is different than addiction, I am asking about tolerance, in an effort to keep the effective dose lower, since once people develop a tolerance, many will start to increase their dosage due to their increased tolerance, making addiction more likely, and ultimately getting off them even more difficult.
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#952898 - 10/31/09 11:20 PM
Re: Valium: I feel wonderful
[Re: NascarGurl]
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GRAND Pooh-Bah
Registered: 09/04/06
Posts: 10286
Loc: NOT 40!
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No. If you develop tolerance to one benzodiazepine, you develop tolerance to them all. There is no merit in rotating them. Whether there is any incomplete cross-tolerance I'm not sure, but if there is, it's likely to be too minimal to consider. There is no way to prevent tolerance to benzodiazepines apart from having time off from them, or taking them on an irregular basis, such as twice per week, for example. Some people will tell you that they have taken the same dose for years and so on; such people are extremely lucky, and are exceptions to the Rules, as occurs in medicine. For hypnotics, you could try replacing doses with a sedating antihistamine, for example, which would help.
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