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#91989 - 04/21/04 11:49 AM Ritalin - Methylphenidate ***
Melody Offline
Moderator
Pooh-Bah

Registered: 03/20/03
Posts: 1378
Loc: DrugBuyers.Com
Please use this thread to discuss Ritalin - Methylphenidate

Thanks

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#91990 - 07/17/04 11:47 PM Re: Ritalin - Methylphenidate
toe Offline
GRAND Pooh-Bah

Registered: 10/09/02
Posts: 812
Loc: MidWest USA

Ritalin is a phenethylamine amphetamine meaning that it is highly abusable (chemical cousin to Ecstasy), so it's Schedule II, and therefore more difficult to get online than a lot of other things.


Methylphenidate is indicated for use in childdren suffering from attention deficit hyperactivity disorder. These children's bodies produce an excess of a "sleepiness" endocrine (forgive, I'm not a medical student doing my pediatricis rotation, I only played one while reading my mother's medical school textbooks as a preteen and then have proceeded to act them out for the past 11 years as the adult sister to an ADHD brother). In response to this excessive sleepiness, the body then "overcorrects" by sending the kids in to ADHD mode. Some "mothers" think that they are being responsible by medicating their children only when they send them to school, where they have to concentrate. Unfortunately. when a kid with ADHD isn't medicated according to plan, the body is going to be in a constantset of overcorrections, and the "unexpected" dose (which is every dose, if a child is only getting his 7am pill, and his lunchtime pill, 5 days a week, when school is in) is always going to result in an extreme reaction.

Take an ADHD kid who has been going wild out to lunch with his family and unable to settle down and eat, running around, introducing himself to all the other diners, and starts to cry when he's forced back to the dinner table. He's not on a proper regimin of his meds. So mommy gives him his medicine. Twenty minutes later, he's passed out over her shoulder. This is no benign drug you are talking about.

As far as your defense regarding "many individuals who have benifited from (off-label) use of methylphenidate for decades," I'm wondering how they got their hands on this drug in the first place. Ritalin has never been prescribed on-label for adult fatigue. There is a good reason for this, too. It's an addictive drug. Using ritalin to "fight fatigue" is a great starter for the definition of its primary theater of abuse: The bedrooms and dorm rooms of students all over the US popping, crushing and snorting, even injecting this drug so that they can stay up all night and (in this, their case is even more legitimate than your's) concentrate on memorizing the anatomy of the mitochondria, pick their way through the most awful, dryest memoir of George Kennan travelling pre-industrial Russia, memorizing 5 pages of conjugations for one-count 'em-one! French verb. And these students risk all the typical health risks associated with the use of speed. Further, because they are students, faced with 700 pages of reading a week and 70 verbs to memorize a week, when they start to feel their minds slow down, they have no choice but to pop another pill. Unlike your garden variety street drugs, methylphenidate poses a special predelication towards abnormal activity in the brain at much lower relative stimulatory doses.

Are you aware that after a routine 10mg morning dose of ritalin in a doctor-supervised ADHD pediatric patient taking all medications according to schedule, shortly after an antidepressant was introduced, the child walked out of his house towards the bus stop and, ten minutes later, fell down and had a grand mal seizure?

In case no one has picked up on this yet, the DEA makes a real arbitrary distinction between C-IIs and C-Is. The only difference between C-IIs and C-Is is that the AMA has guidelines on the use of C-IIs. When you throw out those guidelines, there is absolutely no distinction. Many C-Is, with no AMA guidelines whatsoever, are safer and less mind altering than their C-II counterparts, used AS instructed. (Bearing in mind that an opiate-naive person in acute excruciating pain is liable to get a swift shot of fentanyl- compare that to a hit off a joint or a line of coke) (Not that anyone here has ever used an illegal drug in their precious lifetimes)

Let me just hit you with some spare facts: Because methylphenidate is not a "true" amphetamine, it causes many more complications than its illegal counterparts do to provide the same amount of stimulation. It creates excess electrical activity in the brain that can lead to seizures and causes palpitations. You would be safer using cocaine or dexedrine in "reasonable amounts."

Do not fool yourself. You are abusing this drug. If you are suffering from fatigue, you need to get a CBC done and consult with your doctor on what deficiencies might be causing this. There are many legitimate herbal remedies for your problems, but chances are good that you also need a major lifestyle overhaul including diet, exercise, work, and play. Perhaps modafonil, a medicine that is actually marketed to promate daytime wakefulness might help you out here.

But don't delude yourself. You are abusing ritalin. You are not the only one. ("Hey, kettle. You're black." I could have said at many times in my life.) But you are using a psychologically and physically addictive drug in a manner for which it has never been approved.

I know I sound like a be-yatch, but my data, though infused with emotion is based on facts, clinical trials, personal experience, and our own US Government's studies of young adult drug abuse, as well as multiple editorials that have appeared over the years.


Please go to see your doctor about this fatigue problem. You don't need to risk your heart and your brain to get through the day. (NOt always so easy to believe, I know).

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#91991 - 07/18/04 01:23 AM Re: Ritalin - Methylphenidate
flippie Offline
Member

Registered: 06/13/04
Posts: 99

I would like to underline everything you said in the paragraph pasted below, because it is key:
__
Let me just hit you with some spare facts: Because methylphenidate is not a "true" amphetamine, it causes many more complications than its illegal counterparts do to provide the same amount of stimulation. It creates excess electrical activity in the brain that can lead to seizures and causes palpitations. You would be safer using cocaine or dexedrine in "reasonable amounts."
__

A lot of studies have been done on various phenethylamines (You've read Shulgin's books, right? I'm sure you have, you are obviously well-informed) and it is true that Ritalin is potentially a lot more dangerous than the more powerful "straight" amphetamines.

Interestingly, and I want to say up-front that I feel a little uncomfortable posting this because of the PC-wave that seems to have hit us, but I did read an article that suggested that at the time, Preludin was the prefered drug for WHITE speedfreaks who had their choice and black speedfreaks actively prefered Ritalin. Go figure.

http://www.iprc.indiana.edu/publications/iprc/factline/ritalin.html


Chicago: "The most intensive stimulant abusers...are those who prefer to inject...white IDUs on the North Side are reported to inject phenmetrazine HCl (Preludin)...black stimulant suers on the South Side prefer methylphenidate (Ritalin), or "west coast."

CEWG, Epidemiologic Trends in Drug Abuse, NIDA, 1995.

Weird, isn't it? I mean, say what you will about the DEA, but NIDA's science is usually on the ball, and they are usually quick to admit and retract mistakes.

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#91992 - 07/18/04 08:14 AM Re: Ritalin - Methylphenidate
flippie Offline
Member

Registered: 06/13/04
Posts: 99
Although the DSM would probably refer to replying to one's own post to be some form of dissociative identity disorder, I forgot to mention something that might be mildly significant to the conversation.

Like many people, I take an SSRI daily (Paxil 30mg). I found out years ago that what I had read is correct - when you regularly take an SSRI, the drug Ecstasy will have almost no effect on you - the SSRI attaches it self to some of the same sites that the E wants to get to and blocks it. Not that I would want to because IMHO E is a "do it once learn what you can from it then grow up and move on" type drug, so no loss at all to me. All the less reason to worry about damanging my serotonergenic system in the longterm, which is what MDA neurotoxicity does (I know MDA is not MDMA, but a lot of MDMA/E sold on the streets IS MDA, and now, grotesquely enough, PMA - deadly stuff. During the one long-ago phase in my life when I was shooting a lot of meth, the needle-exchange lady who came out every month with 100 fresh points and a new sharps container said she used to shoot "Love drug (MDA) in the 60s - s-h-e s-p-o-k-e l-i-k-e t-h-i-s to-you - she said her c10h12n2o levels were 40% lower than normal, so even though this is one isolated incident, it does demonstrate what NIDA has been saying about phenethylamine compounds for quite some time now - stay the hell away from them).

I won't get into the kids predosing with the 5HTP and Prozac, although there is some value to both.

So regular users of SSRIs won't get much/any effect (I could eat a gram of pure E and feel very little, except very uncomfortable) and since Ritalin IS chemically related (both being phenethylamines, meaning (naturally) that they are both aminoethylbenzene derivatives, I can't help but wonder if concurrent usage of Ritalin and an SSRI is either dangerous or at the least wasteful.

There is a LITTLE info here, but it is dated (note reference to DSM-IIIr)

http://www.biopsychiatry.com/methyl.htm

Anyway I just thought that might be worthy to mention. If you are a user of SSRIs you might think twice and then a third time about the potentially hazardous material called Ritalin. Besides, that chart in the URL I posted above I THINK showes current street prices. In the ghetto, Ritalin sell for $10 a pill.

Most people here seem to be well-educated and from all different walks of life, but I'd wager that most of you have read Brave New World. I want Huxley's Soma. The ultimate ecstasy drug with no bad side effects. Social and technical progress might slow - but we wouldn't care. Is that wrong? But that is a topic for another thread again...

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#91993 - 07/18/04 12:07 PM Re: Ritalin - Methylphenidate
toe Offline
GRAND Pooh-Bah

Registered: 10/09/02
Posts: 812
Loc: MidWest USA
I am familiar with some of Shulgin's work, and I've also read some of his stuff, as well. However, to be perfectly honest, the PDR and the BNF are my Shephards, I shall not want. . . as a the international lay pharmacologist's prayer goes, I believe.

One thing I would like to clear up regarding my earlier statement about the grand mal seizure brought on by the use two drugs prescribed to a child suffering ADHD and taken as prescribed. One was ritalin, as I made clear above. Unfortunately, my description of the other drug as "an anti-depressant" may have been misleading. The drug in question was Effexor--probably first generation, before XR. Effexor strongly inhibits both serotogenic reuptake and reuptake of norepinephrine, and weakly inhibits dopamine reuptake. (Note that Paxil also inhibits reuptake of all three, but because "it is a potent and highly selective inhibitor of serotonin. . .reuptake" and "has only very weak effects on norepinephrine and dopamine reuptake," it is classified as an SSRI.) Thus, you can see that , as far as potential interactions caused by the stagnation of nuerotransmitters go, Effexor is in quite a different class than any of the selective serotonin reuptake inhibitors. Effexor itself carries a seizure risk--a much higher one than an SSRI-- and thus is drug which should certainly not be taken concurrently with methylphenidate, which fundamentally lowers the seizure threshold.

Unfortunately, I cannot comment on the threat of seizure with Serraxa, the norepinephrine-reuptake inhibitor approved in the past year as the first non-scheduled drug for the treatment of ADHD, either in combination with methylphenidate or without, since my PDR is from 2001. Presumably the AMA's party line on this would be to do as much to discourage concommitant use of the two as possible, regardless of the safety issues.

However, I don't mean to dismiss any concerns that you might have about the possibility of a neurological event occuring during concommitant use of an SSRI and methylphenidate. I'm sure anyone who has ever had the experience of going on OR off an SSRI, especially those with the shorter half-lives (like Paxil or Zoloft), in particular in the care of a careless doctor, couldn't help but notice unusual neurological activity. Particularly evident in the clinical trials were neurological events including: numbness and tingling sensations (paresthesia) and overall bodily weakness (asthenia), tremors, excessive tiredness, dizziness, insomnia, and nausea. These side effects accounted for dropout rates, amongst the different trial groups tested, between 10 and 20%. Further study shows that the likelihood of experiencing all of these adverse neurological effects is dose dependant.
KISS (that's to me, BTW) Paroxetine obviously does a number on your brain, and not just in the ways you want it to. The adverse neurological events mentioned are only those that would be considered extremely common. I would definitely argue that Paxil let's your brain's guard down, which means lowering the seizure threshold.

Most SSRIs do this to a greater or lesser degree, and if you have ever had a grand mal seizure, you are hyper-vigilant about anything that might strike you as an unusual neurological event. In general, if you feel like your brain might be creeping on you, let's hope you--or anyone, for that matter--would have the sense not to add ritalin. Because, while SSRI's may lower the seizure threshold, methylphenidate actually causes them.

However, my inquiries have yet to produce an instance with an SSRI such as that with the Effexor. In the PDR records of the SSRIs that I have looked at (and I have looked at almost all of them, because I have been on almost all of them) I have found no SSRI that will send you to the hospital if you combine it with a drug in a reasonable amount, unless that drug is mentioned on a little yellow sticker on your prescription bottle.

So, chances are, Paxil and 10mg of ritalin a day are not going to give you a seizure or arrythmia. Nonetheless, please bear in mind that 1) Paxil causes drowsiness, fatigue, and general weakness in a very large percentage of it's patient population, and the higher your dose, the stronger the side effects. 2)Any doctor who prescribes Paxil should be willing to reckon with these adverse affects. . .If the benefits of the medication outweigh the side effects, the doctor should be ready and willing to prescribe a safeadult alternative to combat the adverse affects. Otherwise, alternate medications should be pursued.

Because it is a mind-altering drug, a stimulant, it's simply not a good idea to self administer methylphenidate if you are in treatment with an anti-depressant. What goes up, must come down.
_________________________
"It's the end of the World as We Know it. . ." -REM "and I'm seeking asylum in Canada"-toe

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#91994 - 07/22/04 04:31 PM Re: Ritalin - Methylphenidate
Sidamo Offline
Newbie

Registered: 11/25/03
Posts: 24
In response to Flippie's opinion on the detriments of Ritalin (methylphenidate) which is quoted here, I wrote some comments in rebuttal.

Please see this discussion thread for my comments.

In a nutshell, I respectfully disagree with Flippie about the relative danger of Ritalin vis a vis many other helpful drugs. However, I understand the point of view of those who feel strongly that Ritalin is bad. In my experience, it can be a real help to those with a genuine need, and the ability to regulate themselves.

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#91995 - 07/22/04 10:01 PM Re: Ritalin - Methylphenidate
flippie Offline
Member

Registered: 06/13/04
Posts: 99
Sidamo:



Thank you for the great post. I wish that I could argue with you on the subject, but it looks like you have me outthunked at this point. I cannot argue that a lot of people are genuinely more productive and socially acceptable when they are on Ritalin, and not that I am admitting that I have ever used it illegally myself, I have probably once or twice stumbled on the edge of a carpet and accidently shoved one or two up my nose.



I do know plenty of people who happily buy them on the black market, and I posted a URL earlier that showed the results of a study that indicated that the black community prefered Ritalin to Preludin, which was the preference of white people in the area. I realize that sounds weird, especially to anyone who had an opportunity to try Preludin - I wonder if this site will automatically blank out the phrase "spontaneous orgasm the second the needle comes out"



Gotta love those phenethylamines.

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#91996 - 01/29/05 09:55 PM Re: Ritalin - Methylphenidate
freddds Offline
Stranger

Registered: 01/22/05
Posts: 5
Loc: LA
Quote:

This forum is not to discuss suppliers. This thread is to discuss Re: Ritalin - Methylphenidate and not the compnaies offering it. We have other forums for that.
Thank you for your support.





Edited by Melody (08/08/05 03:31 PM)

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#91997 - 01/30/05 07:08 PM Re: Ritalin - Methylphenidate
AngelWolf13 Offline
Veteran

Registered: 07/07/04
Posts: 464
Loc: w/ my '91 EG-4 in SoCal....
i am glad they don't make me take ritalin or concerta anymore. dexedrine is without a doubt and hands down the most, if not the only effective treatment for my adhd (severe). been on the same daily dose for years, what a difference, and a lifesaver!

from what i am gathering on this thread, it seems to me that dexedrine is way safer than ritalin. if this is true, then why does ritalin seem to be easier to obtain than dexedrine? does this have to do with the cost of manufacture? the availability of chemical components (seems unlikely), perhaps? it seems, nowadays, the safer the drug, the less likely it will be prescribed....

anyway, thanks all!

cheers, angel

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#91998 - 01/30/05 09:20 PM Re: Ritalin - Methylphenidate
freddds Offline
Stranger

Registered: 01/22/05
Posts: 5
Loc: LA
WHERS DID you come up with this ??


Thanks Fred

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#91999 - 02/05/05 09:51 AM Re: Ritalin - Methylphenidate
BamaChica Offline
Banned. Moderator at europevendor.com. We consider mods as reps for a site. This user not allowed to post as rep.
Pooh-Bah

Registered: 05/28/04
Posts: 896
Loc: Resident Bad Girl....
Angel... i would like to know more about Dexedrine for your ADHD...my son has uncontrollable ADHD..or so that is the "label" they have given him. He is 11 and has been on Concerta,Strattera,Metadate,Ritalin, and Adderol, and now he is back on Metadate. He isnt really hyper, nor is he "bad" like you see some kids with behavior problems..He is near genius level IQ like most people with ADHD, and its just that he cannot seem to pay attn in school, and his Dr. is thinking that he falls in the 20% of people who's ADHD is not controlled by meds. he hasnt mentioned the dexedrine, so Im wondering if this is something they only use in Adults? Any info you can give is appreciated! thanks!
Holli

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#92000 - 02/06/05 03:07 AM Re: Ritalin - Methylphenidate
AngelWolf13 Offline
Veteran

Registered: 07/07/04
Posts: 464
Loc: w/ my '91 EG-4 in SoCal....
hi holli,

i am sorry to hear your son has adhd. actually, it sounds more like he has add (sans the hyperactivity). both add and adhd are treated effectively with the stimulant meds you indicated above. what i didn't know is that 20% of adhd sufferers are not helped with the adhd meds!

myself, i have had pretty bad adhd all my life. doctors usually say that kids w/ adhd grow up into adults with add, that the hyperactivity part wears off with age. i'm like, what, 37, and w/o my meds i am still extremely hyperactive. it is ridiculous, honestly, for someone my age to be like that.

throughout my life these are the meds i have taken for the condition and how they affected me...

cylert (pemoline)... no good, might as well have taken caffeine pills, made me jittery, did nothing to help me focus.

ritalin (methylphenidate)...helped a little, calmed me down, somewhat effective for my "hyperness", but didn't help my concentration. wasn't completely comfortable on it.

concerta (methylphenidate, sustained release)... almost exactly the same as ritalin, but, for me, anything sustained release seemed to be a lot less less effective, frankly. sounds strange, but my doctor understood that. i asked him if i could try dexedrine or adderall so he put me on dexedrine for a month.

dexedrine (dextroamphetamine)... wonderful! was effective 15 minutes after the first dose. i was calm and my concentration, while still not perfect, was dramatically improved. no temper tantrums (honestly, even at my age, i used to wake up and be on a rampage and bouncing off walls, still do when i forget to take my morning dose). i actually eat well and sleep better on dexedrine. the only problem i have with it is that, especially in the morning after i take my firse dose (2 x 10mg.) i am so much more calmer than i am normally, i frequently take a nap. it's hard to explain, but it doesn't make me feel light-headed or woozy or anything like that. i guess, just i feel my mind is clearer and because i am so active/angry otherwise, once my mind has had a chance to calm down, i tend to breathe easier and relax. plus, i am an "active" sleeper.

when i told my doctor how wonderful the dexedrine was, i asked him if the next step would be adderall. he said, no, if the dexedrine was effective, no need to try the adderall. plus, while adderall is essentially almost the same thing, dexedrine is a "purer" form of amphetamine, and because of that i figure less "other" unwanted effects as opposed to adderall which, imo, is "adulterated" dextroamphetamine. i surmise that adderall was invented #1 to make money on a new patent on an old idea, and #2 to make dextroamphetamine less "abusable". iow, to put a bunch of other [censored] in it that not only make it in essence weaker than the original, but also to discourage abuse by making it "uncomfortable" at high doses (i.e. the amphatime derivatives and other junk they put in there to make one jittery and anxious at higher doses, something pure dexedrine won't do) and harder to crush, snort and/or inject. either way, if there's all that other rubbish in the adderall, there is a good possibility i wouldn't feel as comfortable on it as i do on dexedrine. another thing to consider is your son might be like me in the sense that perhaps the sr (sustained release) or xr (extended release)stuff just isn't effective. that's usually what adderall is. i really don't get ups and downs on the immediate release stuff, so that's no problem with me.

strattera, i haven't tried, but i do not have much faith in non-amphetamine stuff. my doctor told me that though it would be easier to rx strattera as it (like that damned cylert) is not a sch II drug , he highly doubted it would be effective for me anyway, so he didn't waste my time. (i had a really great doctor!)

metadate, afaik, is also methylphenidate and if ritalin and concerta wasn't effective for him, i can't see why in the world his doctor would rx this! don't mean to be rude to his doctor, but i think that is silly. and, no, dexedrine isn't something they use only for adults. i think you should ask your doctor about letting your son give them a try. i mean it, it was the ONLY thing that ever worked for me, truly a lifesaver!!! oh, before i forget, i wanted to ask you if your son thought any one of the drugs he has tried has been more effective than the others and if so, in what way(s)?

the really frustrating thing about add/adhd, and i'm absolutely sure your son feels this way, luckily you're a good mom and caught it and are proactive in it's treatment (bravo to you!), is that even though he has a very high iq, it is tough getting anything done effectively or finish anything. the problem is we think faster than we are able to do things or talk, and we can't catch up with our brains. we think of a million things all at once and it is [censored] near impossible to train ourselves to think about one thing at a time. on dexedrine i am down to 50 or 60 thoughts at once. i don't normally ever tell people this but i score a consistant 139 on iq tests, even with my adhd, and it drives me crazy that i can't ever get anything done! i am certain your son feels the same way, and as i can relate, i do sympathize. it's improtant that you understand this. i had a very traumatic childhood at home, partly due to undiagnosed adhd.

see? when i am not on my dexedrine? it took me no less than 2 and a half hours to complete this ONE post. after every couple of sentences i either start looking at other things in the room or i leave to do something else. i cannot believe it is 3:00 am already! more like 3 hours then... if i think of anything else i'll try to remember to post it. please let me know how things go with the doctor, ok? good luck and best wishes to you and your son.

cheers, angel

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#92001 - 02/06/05 03:56 AM Re: Ritalin - Methylphenidate
AngelWolf13 Offline
Veteran

Registered: 07/07/04
Posts: 464
Loc: w/ my '91 EG-4 in SoCal....
Quote:

..He is near genius level IQ like most people with ADHD, and its just that he cannot seem to pay attn in school, and his Dr. is thinking that he falls in the 20% of people who's ADHD is not controlled by meds.




hi holli,

i just reread your post again, pondering over what you said about your son's doctor's opinion that the meds your son had been on were ineffective.....

i have another thought. i cannot say, of course, whether or not your son has add. if he does then it should be treated by all means. but, i was thinking that, perhaps, your son is simply too advanced for his classes. it is known that if a child is very intelligent, in your son's case near genius level, then he would have problems paying attention in class because he is bored. a class that doesn't really teach him anything can't stimulate him. i wonder what would happen if he were allowed to jump ahead a grade or two. i don't know of that would pose new social problems, but he might be more attentive if his mind was challenged. he sounds like a very bright young man. you must be very proud of him!

just a thought. please, still keep me posted.

angel

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#92002 - 04/20/05 09:21 AM Re: Ritalin - Methylphenidate
DMDIPP Offline
Stranger

Registered: 03/23/05
Posts: 3
This forum is not to discuss suppliers. This thread is to discuss Re: Ritalin - Methylphenidate and not the compnaies offering it. We have other forums for that.
Thank you for your support.

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#92003 - 04/20/05 09:49 AM Ritilan---Methylphenidate
cleo911 Offline
Pooh-Bah

Registered: 08/21/02
Posts: 1324
Loc: Warri, Nigeria
This forum is not to discuss suppliers. This thread is to discuss Re: Ritalin - Methylphenidate and not the compnaies offering it. We have other forums for that.
Thank you for your support.


Edited by Melody (08/08/05 03:35 PM)

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#92004 - 04/21/05 11:18 AM Re: Ritilan---Methylphenidate
RZeta Offline
Stranger

Registered: 10/06/04
Posts: 13
I used to be on methylphenidate for ADD for quite a long while. I was on 10 mg of the generic IR methylphenidate TID. The problem with methylphenidate, however, was that despite my increase in attentive qualities, the drug only lasted an hour...if that. I have since switched to the (d)-amphetamine SR capsules (generic for Dexedrine Controlled-Release Spansules) and the difference is night and day. D-amphetamine is much smoother than methylphenidate and has far fewer cardiac and PNS side-effects. As for Adderall, I was on Adderall a long time ago (Adderall XR did not even exist at this point) and found it to be about the same as enantiopure (D)-amphetamine, but with more cardiac effects (bad). In my opinion, there is really no need for Adderall to even be on the market (it could easily be replaced by difference formulations of (d)-amphetamine). The only reason it is on the market is one reason and one reason alone: $$$. Since (d)-amphetamine is long off-patent, Shire "invented" a new formulation of amphetamine salts and called it Obetrol (for "obesity-control"), but then soon shifted the indication to ADD and it took off like a rocket.

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#92005 - 05/29/05 11:22 PM Re: Ritalin - Methylphenidate
shami Offline
Stranger

Registered: 04/04/04
Posts: 2
Many of you seem to know a great deal about these meds. i was woundering if anyone had an opinion about my situation. i am prescribed Lamictal (like nerotin) and Cymbalta for bipoler. but i take tremidol for pain and sometimes a bit more because it feels good. but i read that tremadol could lower the seizure threshold.

tremidol comes with the warning that you shouldn't take it when taking SSRI's because it can result in manic states of seizures.

does anyone know anything about the relationship between these things? also, i was looking for the safest stimulant considering all of the above, but from what i read in this thread the leagal stuff (ritalin) is more risky than the street stuff (meth amphed.) with the risk centered arond the seizer issue.

Thx!

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#92006 - 10/13/05 03:42 PM Re: Ritalin - Methylphenidate
quizonlee Offline
Stranger

Registered: 08/29/05
Posts: 1
I've been prescribed ritalin ( 30mg daily) for two months. And over the course of those two months I went into a paranoid psychosis which subsided once I was taken off of ritalin. Be careful.

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#92007 - 11/06/05 08:05 PM Re: Ritalin - Methylphenidate
guygusse Offline
Stranger

Registered: 09/05/05
Posts: 2
This forum is not to discuss suppliers. This thread is to discuss Re: Ritalin - Methylphenidate and not the compnaies offering it. We have other forums for that.
Thank you for your support.


Edited by Melody (01/02/06 04:32 AM)

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#92008 - 11/06/05 09:55 PM Re: Ritalin - Methylphenidate
MicSlyness Offline
GRAND Pooh-Bah

Registered: 08/12/05
Posts: 1769
Loc: Water Closet
There are many IOP's that offer it. Here is a link to the thread.

http://www.drugbuyers.com/freeboard/postlist.php/Cat/0/Board/intquestions

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#92009 - 11/08/05 04:11 PM Re: Ritalin - Methylphenidate
toe Offline
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Registered: 10/09/02
Posts: 812
Loc: MidWest USA
Quote:

Many of you seem to know a great deal about these meds. i was woundering if anyone had an opinion about my situation. i am prescribed Lamictal (like nerotin) and Cymbalta for bipoler. but i take tremidol for pain and sometimes a bit more because it feels good. but i read that tremadol could lower the seizure threshold.

tremidol comes with the warning that you shouldn't take it when taking SSRI's because it can result in manic states of seizures.

does anyone know anything about the relationship between these things? also, i was looking for the safest stimulant considering all of the above, but from what i read in this thread the leagal stuff (ritalin) is more risky than the street stuff (meth amphed.) with the risk centered arond the seizer issue.

Thx!




Well, Cymbalta is an SNRI (like Effexor), except that the norepinephrine reuptake effects kick in at a lower dose, then the serotonin reuptake effects.

Lamictal is an anti-convulsant that's also approved to treat bipolar depression (the only drug other than lithium specifically approved to do so, unless the FDA has done some work in the past few months.

Tramadol is a drug that can induce seizures when taken in moderately large quantities (400mg) all on its own. But combining that with an anti-depressant with serotonin reuptake effects (including Cymbalta) definitely lowers the threshold further. I would have a serious talk with the docs and your pharmacist on this one-- if your Tramadol is prescribed. Get a different painkiller.

I suppose the lamictal offers you some "protection" against seizure activity, but not a whole heLL of a lot. It's main anti-convulsant strength is against a type of seizure that is completely different from the "tonic-clonic" grande mals we are thinking about.

Since you suffer from a major neurochemical disorder, fooling around with any kind of mind altering drugs on the side is really, well, a STOOPID thing to do. Any kind of speed is just not a good idea.

If you think you have AD(H)D, the party line is that you ask to be tested for it, then get on the RIGHT meds (adderallXR is the flavor of the month) under a doctor's supervision .

Many times, BP is comorbid with ADHD, so you might very well have it.

You might not, and if you self-medicate with any serious stimulant along with your dX and scripted meds, you risk both seizure activity and psychotic episodes (as mentioned above).

It all depends on your intentions. Obviously none of these drugs cause a statistically significant enough proportion of the population's heads to explode to be taken off the market (with the exception of Cylert, which causes your liver to eat its self). However, the instance of stimulant-abuse-induced psychosis is pretty well documented.

It's completely up to you.
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"It's the end of the World as We Know it. . ." -REM "and I'm seeking asylum in Canada"-toe

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#92010 - 12/03/05 07:15 PM Re: Ritalin - Methylphenidate
JBargsbeer Offline
Stranger

Registered: 11/28/05
Posts: 7
maybe someone here can help me with some info ....a friend of mine told me that Ritalin was actually used as a weight loss drug in the 60's and 70's if so ....is it effective at helping people lose weight ?.

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#92011 - 12/07/05 02:56 AM Re: Ritalin - Methylphenidate
gop Offline
Board Addict

Registered: 10/19/05
Posts: 329
Quote:

maybe someone here can help me with some info ....a friend of mine told me that Ritalin was actually used as a weight loss drug in the 60's and 70's if so ....is it effective at helping people lose weight ?.




I have heard ritalin being used for weight loss, you have to weigh the side effects though. Since ritalin is essentially speed. The side effects have been posted above.
What's more important to you, only you know. There are other diet meds, if you haven't tried them, may I suggest you start there, you may find great results. Whatever you decide, best to you.

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#92012 - 12/07/05 05:55 AM Re: Ritalin - Methylphenidate
aliceellen1 Offline
Veteran

Registered: 06/20/05
Posts: 506
Loc: Florida but always a New Yorke...
Toe - that was an excellent and informative post. Thank you for it. Taking things like ritalin can cause many more problems than people realize. And self-diagnosis of ADHD is a complete No-No in my book. I have it and went through hours of testing and my doctor monitors me like crazy. You just may have saved someone life.

Peace,
Alice
_________________________
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#92013 - 12/07/05 06:35 AM Re: Ritalin - Methylphenidate
dollhog Offline
Old Hand

Registered: 07/06/02
Posts: 286
Loc: california
HI, I seem to be in a similar boat such as you.
I too have Bipolar Disorder.
I use Wellbutrin, Lamictal, Seroquel and Trazadone.

It sounds like a lot, but it is a magical cocktail for me.
No more mania and no more depression.

However, about 6 months ago I was having trouble remembering the slightest thing. I'd walk into a room to do something and immediately forget. It was horrible.

My doc put me on 5mg of generic Ritalin every morning. Voila, my concentration is back. No, I do not get hyper and (unfortunately) it does nothing to decrease my appetite.

I know that this drug, as so many others, can be misused. But please realize that this medication is a godsend to many. Downing the use of Ritalin as I've been reading here is really not much different than those who down the use of opiods to treat pain.

I, too, would not self medicate with Ritalin but if your doc suggests it, it's worth trying.


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#92014 - 12/07/05 08:09 AM Re: Ritalin - Methylphenidate
barf Offline
Banned: shill, constanlty plugging email sources...

Registered: 11/23/05
Posts: 195
Adderall is both dextro and levo forms of the same drug. Not really an adulturant. Unless your left hand is an adulturant to your right hand. It is really just the old benzedrine, except its solidified w/h some sugars instead of all sulfates.
All pills have fillers. If your foolish enough to inject ritalin, realize water soluable binders cross over into the liquid your injecting. They can clog blood vessels in your eyes and lungs, reducing how well you can see and breathe.

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#92017 - 12/08/05 01:45 PM Re: Ritalin - Methylphenidate
investor Offline
Banned: too much drama and claiming everyone is shorting him. False posts to get more meds, multiple

Registered: 11/19/05
Posts: 311
is ritalin ever refered to as "greenies" ? I have read its the speed that pro athletes use to get a pick me up. Not sure if it was ritalin or not since it was mentioned it is a speed type product. If not, what are those "greenies" ?

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#92018 - 12/08/05 01:51 PM Re: Ritalin - Methylphenidate
OldandWorn Online   shocked
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Registered: 09/21/03
Posts: 8650
Loc: LoFi Pool Hall, 12th & Vine
Reading sports lore and recent articles, greenies are not ritalin. I don't know if baseball players are taking green tablets or its slang. But it is definitely real speed, not ritalin. Probably something closer to adderal. Speed kills, stay away.

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#92019 - 12/08/05 08:19 PM Re: Ritalin - Methylphenidate
barf Offline
Banned: shill, constanlty plugging email sources...

Registered: 11/23/05
Posts: 195
Focalin. Sounds like a STD. Or maybe that would be focalot. But like dextro and levo amphetamine, its just one of the optically active isomers of ritalin. Its segregated like dexedrine is, compared to the old benzedrine SKF used to make. Ritalins a soup of all the isomers, both the stronger and the weaker. But as another poster said, everyones body chemistry is different. Some of us are left handed, some right handed.
Or as angel pointed out. Another way to tweak a few more years out of a patent. Another day, another million.

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#92020 - 12/08/05 08:27 PM Re: Ritalin - Methylphenidate
jockey Offline
Enthusiast

Registered: 11/01/05
Posts: 266
i have some friends in law school who say law students pay up to 25.00 per pill to study the day before and take the morning of the test that is crazy to pay money like that somewhere are some rich children who cant pay attention

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#92021 - 12/09/05 10:04 AM Re: Ritalin - Methylphenidate
dollhog Offline
Old Hand

Registered: 07/06/02
Posts: 286
Loc: california
Hi, I think your response was to someone else. I never mentioned injecting Ritaling.
Just to clear that up.

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#92022 - 01/28/06 03:15 PM Re: Ritalin - Methylphenidate
morphia Offline
Enthusiast

Registered: 12/21/05
Posts: 187
Loc: Pacific Northwest
I'd like to post my experience with Ritalin. I ordered some from an IOP to treat some self diagnosed ADD symptoms. I took my first dose a couple days after receiving it and was surprised at how strong it was: it felt just like the pleasant stimulation one would get from any of the amphetamine type drugs, I thought "what a great drug, I can focus, I'm in a good mood, what more could you ask for?" This was one 10mg pill BTW. Anyways that lasted about 2 hours at which point I started to feel agitated and kind of down, this progressed to downright sadeness/depression, I was tempted to take another dose but resisted. Later on I had to take 30mg valium to neutralize the depression and over stimulation. I gave it another try two days later and same deal, except I took another 10mg after the first wore off. Today I took my last dose, 20 mg, none of the positive effects but got a headache and felt kinda down. I threw the rest of the pills in the toilet. These for me seemed like a sure fire way to get totally hooked on valium to nullify the unpleasant effects. I never throw useful drugs away but I knew that after a couple days my brain would forget about the terrible crash but remind me of the fun "euphoria" and I would take them again, for me at least, amphetamine like stimulants are bad for my brain, I hate feeling depression because a drug is wearing off. I could not imagine giving this stuff to my little nephews with their innocent, clean little brains, what a crime.

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#92023 - 01/28/06 03:19 PM Re: Ritalin - Methylphenidate
Ruggie Offline
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My son was on ritilan for 2 weeks and lost 8 lbs in that time and his aggitation when the med wears off was beyond belief, I switched had the doc switch him to concerta and he really doesn't have that aggitation like with the ritilan, see ritilan is short acting and concerta is time released over a 12hr period and also he didn't lose his appitite on concerta and is starting to put that weight back on, he is 6 and 4'4" tall and he was 56 lbs and he went to 48 lbs and that is not good at his hieght, just thought I would share about the aggitation part, since that was what mostly bothered me, and I know it had to have bothered and confused him, and I could not put my child through that.
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#92024 - 01/28/06 06:03 PM Re: Ritalin - Methylphenidate
Daeshay76 Offline
Banned: multiple ID's. Same user as My2Boyz.

Registered: 03/22/04
Posts: 1684
Just curious about something....I have severe CFS and was on provigil 200mg 2 times a day until it did not work any longer and could not be taken more than 2 times a day (thats what my doc said) so I placed a order through a IOP for 10mg of Ritlain....I am wondering if it is safe to take as needed when the CFS is really bad? I do not plan on taking this med everyday just as needed. I have read the whole thread and now kinda scared to take it when I get it. It seems like adderall is safer and better in the extended release form. I have thought for awhile I may have adult add/adhd but not sure and my doc would never test me or refer me to be tested. So I guess I am self medicating myself and also self treating my CFS as well. But what is one to do when their doc does not what to help? I just want to know if Ritlain is safe to take as needed instead of on a daily basis. Also what is the max dose one can take in a days time? I will probably only take 10mg once a day as needed no more because I do not want this to be something I have to take to be normal...ya know? any info would be great....thanks
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#92025 - 01/28/06 07:03 PM Re: Ritalin - Methylphenidate
morphia Offline
Enthusiast

Registered: 12/21/05
Posts: 187
Loc: Pacific Northwest
Try one of the 10mg pills, maybe it will effect you diiferent than it did me. One thing I've learned about stimulants is they don't "give" you anything, energy, happiness, alertness etc. They take what you were going to use tomorrow and give it to you now, understand? You can keep taking them but eventually you will have to pay the piper and feel the opposite of any good feelings they gave you. I for one hated the way they made me feel all sad when they wore off, I wasn't abusing the stuff either, just a single 10 mg pill, one day, two pills on another occasion.
But of course YMMV.

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#92026 - 01/28/06 08:23 PM Re: Ritalin - Methylphenidate
Daeshay76 Offline
Banned: multiple ID's. Same user as My2Boyz.

Registered: 03/22/04
Posts: 1684
YMMV??? sorry dont understand the letters
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#92027 - 01/29/06 01:32 PM Re: Ritalin - Methylphenidate
morphia Offline
Enthusiast

Registered: 12/21/05
Posts: 187
Loc: Pacific Northwest
Your Mileage May Vary: your experience may well be different than mine.

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#92028 - 02/09/06 07:32 AM Re: Ritalin - Methylphenidate
investor Offline
Banned: too much drama and claiming everyone is shorting him. False posts to get more meds, multiple

Registered: 11/19/05
Posts: 311
I just recieved some Ritalin, 10 mg tablets and took one about an hour ago. I can say that I feel much more alert and awake but not "speedy", it feels good and I always get the afternoon "snoozies" so I am sure I will take 1 this afternoon. I figured I would give it a try, I did try dexidrine but since its so hard to get, I figured Ritalin was the next best thing, I actually like it better, not as strong as the dexidrine but is working well.

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#92029 - 08/07/06 06:29 AM Re: Ritalin - Methylphenidate
MrBook Offline
Stranger

Registered: 02/05/06
Posts: 15
I found Adderral to be more speedy than ritalin. Also a lot more powerful and long lasting, the feeling of euphoria also lasted much longer. I find Ritalin almost the same as adderral just less powerful, and shorter lasting. Which is why I prefer it, this way I know when I will come down, and can atleast make sure I will get sleep.
I have found as long as one sleeps, instead of allowing these stimulants to ruin your sleep schedule and take one subsequently extra the next day to not be tired, its easy to control the ups and downs. It was when I allowed these drugs to ruin my sleep that got me really edgy and agitated.

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#92030 - 08/07/06 06:49 AM Re: Ritalin - Methylphenidate
kelbel2 Offline
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Registered: 09/22/05
Posts: 1402
Just curious what the adult dose for adderall and ritalin is. I have ritalin for sedation effects from opiods.
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#92031 - 08/31/06 12:17 AM Re: Ritalin - Methylphenidate
jimc123456 Offline
Stranger

Registered: 05/30/03
Posts: 3
Just curious here, I have noticed, that it makes me extremely horny, I had to ask my doctor to switch me to an amphetamine, which does not have this effect (it is not just me, or I would just figure I am an exception). Can anyone explain this? Why the amphetamine does not have this effect, but the Ritalin does?
I am totally earnest here! No foolin'
Thanks
Does Ritalin make you Randy?
Only one choice allowed


Votes accepted starting: 08/31/06 12:17 AM
View the results of this poll.

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#92032 - 01/21/07 08:34 PM Re: Ritalin - Methylphenidate
slepinosa65 Offline
Veteran

Registered: 03/18/04
Posts: 467
I've taken about ritalin, and every other ADD med, and I always have a problem with tolerance. Does anyone know how to prevent tolerance to these type of meds?

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#92033 - 01/21/07 09:13 PM Re: Ritalin - Methylphenidate
nephro Offline
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Registered: 09/04/06
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Loc: NOT 40!
There is no way apart from careful dosing, regularly making sure each dose has the same effect.

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#92034 - 02/24/07 10:01 AM Re: Ritalin - Methylphenidate/Provigil
kserah Offline

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Registered: 10/05/04
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Loc: In the moment
Does anyone have any experience or know anyone who uses Provigil? I know what I've read about it but never heard from anyone that uses it what the side effects are.

I'm curious because I've been seeing it given to people with brain trauma (accidents) or CVA's, as well as Ritalin and I'm curious about long term results.

Thanks.
_________________________
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And if you can, dance; nothing lifts the spirit higher.



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#92035 - 02/24/07 10:10 AM Re: Ritalin - Methylphenidate/Provigil
sincity Offline
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Registered: 06/07/03
Posts: 1443
I have it, I've taken it, I've been taking it again.
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#92036 - 02/24/07 10:20 AM Re: Ritalin - Methylphenidate
lolajones Offline
Enthusiast

Registered: 02/04/03
Posts: 190
I took Tramadol (Ultram) for 4 years with my SSRI and had no problems except it quit working for pain. I had to stay on a low dose (1 pill a day) though. I would imagine higher doses you would have problems.

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#92037 - 04/22/07 02:34 PM Re: Ritalin - Methylphenidate
sinestr0 Offline
Stranger

Registered: 03/29/07
Posts: 5
Dont know if this the right forum- but anyone know of any sources other than PuraVida?
PM me if you do, thanks.

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#92038 - 04/29/07 09:36 PM Re: Ritalin - Methylphenidate
korvknarken Offline
Stranger

Registered: 10/06/06
Posts: 10
Loc: Sweden
Quote:

Dont know if this the right forum- but anyone know of any sources other than PuraVida?
PM me if you do, thanks.




I'm not allowed to PM yet... but I have bought from www.offshore-pharma.com It's expensive but you'll get your meds at least I did. I don't know why it's not listed in the International list because it's well known at DB, I found it here a while back.

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#92039 - 05/29/07 07:04 AM Re: Ritalin - Methylphenidate
JLaug10092 Offline
Member

Registered: 05/15/06
Posts: 110
Loc: Nashua
Quote:

I found Adderral to be more speedy than ritalin. Also a lot more powerful and long lasting, the feeling of euphoria also lasted much longer. I find Ritalin almost the same as adderral just less powerful, and shorter lasting. Which is why I prefer it, this way I know when I will come down, and can atleast make sure I will get sleep.
I have found as long as one sleeps, instead of allowing these stimulants to ruin your sleep schedule and take one subsequently extra the next day to not be tired, its easy to control the ups and downs. It was when I allowed these drugs to ruin my sleep that got me really edgy and agitated.




^^^100% agree. I just recently got some Ritalin as I have been having trouble focusing on work and also get the afternoon "snoozies" as someone else posted. I have tried both Adderral and Ritalin in the past (both some years ago) and always found the Ritalin to be preferable. Making sure you sleep and eat is important, LOL.

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#574648 - 10/04/07 08:23 AM Re: Ritalin - Methylphenidate/Provigil [Re: kserah]
InvertedBob Offline
Enthusiast

Registered: 10/25/05
Posts: 219
Loc: USA
 Originally Posted By: kserah
Does anyone have any experience or know anyone who uses Provigil? I know what I've read about it but never heard from anyone that uses it what the side effects are.

I'm curious because I've been seeing it given to people with brain trauma (accidents) or CVA's, as well as Ritalin and I'm curious about long term results.

Thanks.

Hi Kserah. I take Provigil. I have sleep apnea and it helps for me to stay awake and concentrate a little better during the day.
I don't notice any big side effects. I don't feel jittery or wired. It's hard for me to judge its affect on my sleep because I don't sleep very well to begin with, but from what others have said, it doesn't seem to interfere with sleeping, either.
HTH

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#638442 - 01/26/08 10:08 PM Re: Ritalin - Methylphenidate [Re: Melody]
hazmat911 Offline
Stranger

Registered: 08/21/05
Posts: 4
First Post,
Is There any pharms that supply ritalin, concerta, adderall, ect. Having tough time. Moved recently and of course new doc looks at me cross eyed when i ask him about going back on ritalin. Having a rough go without it, can't focus at all at work anymore. Any help is appericiate

Thanks,
Rob

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#638454 - 01/26/08 11:29 PM Re: Ritalin - Methylphenidate [Re: hazmat911]
Toufas Offline
Newbie

Registered: 06/22/07
Posts: 32
ritalin yes, concerta and adderall, havent found anything that looks legit.

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#638458 - 01/26/08 11:55 PM Re: Ritalin - Methylphenidate [Re: Toufas]
hazmat911 Offline
Stranger

Registered: 08/21/05
Posts: 4
Toufas can you point me in the right direction, can't send you privite chat yet not enough posts


Edited by hazmat911 (01/26/08 11:58 PM)

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#638478 - 01/27/08 12:45 AM Re: Ritalin - Methylphenidate [Re: hazmat911]
scruf Offline
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Registered: 03/21/05
Posts: 2175
Loc: pacific nw
better yet Toufas - POST it for everybody. share this type of info. that's the main idea of the board. might as well, neither one of you can PM yet anyway.

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#638541 - 01/27/08 07:31 AM Re: Ritalin - Methylphenidate [Re: scruf]
Toufas Offline
Newbie

Registered: 06/22/07
Posts: 32

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#720299 - 06/27/08 12:01 PM Re: Ritalin - Methylphenidate [Re: ]
stever11 Offline
Banned. Rude, unpolite, and nasty posts with no content value
Journeyman

Registered: 05/10/08
Posts: 79
Loc: High Desert
i just saw adderall on pharmacyworldmx.com. but i dont know if they are a reliable pharmacy although they do have some good feedback---if you want to roll the dice let us know how it turns out

adderall is pure speed combo of all the types look it up in the PDR.. i worked at a pediatric clinic and i didn't know what adderall or concerta were but i knew they were with the benzidrine and ritalin scripts.. so i looked it up...i asked the DR. your giving kids speed? she freaked and said studies show that kids do better on the meds...i said "yeah Hitler ran the war better on his meds too" got fired but i would never give kids speed---what are they thinking?


Edited by stever11 (06/27/08 12:09 PM)

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#720390 - 06/27/08 03:00 PM Re: Ritalin - Methylphenidate [Re: stever11]
Bluefairy Offline
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Registered: 06/27/07
Posts: 1469
Loc: Deep in Dixie
They are thinking that is an effective drug when used properly.
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Stubbornness does have its helpful features. You always know what you are going to be thinking tomorrow. ~Glen Beaman

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#720412 - 06/27/08 03:24 PM Re: Ritalin - Methylphenidate [Re: slepinosa65]
recruiterlo Offline

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Registered: 05/01/06
Posts: 1082
Loc: here for now
take breaks from ritalin is the only way from going intolerant and abusive -- for me, anyway. i notice lot's of bashing and i have problems with it -- that said, never could have been focused enough without it. definitely helps me make a living. sleep is ESSENTIAL.
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#721302 - 06/29/08 01:53 PM Re: Ritalin - Methylphenidate [Re: recruiterlo]
drewls Offline
Newbie

Registered: 05/17/08
Posts: 30
Please forgive me if I'm prying, but how long a break do you take? Do you change over to something else during the break or just cut it off for a while?

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#778409 - 10/04/08 09:33 AM Re: Ritalin - Methylphenidate [Re: drewls]
trex9 Offline
Stranger

Registered: 09/06/08
Posts: 12
Loc: New Mexico, USA
First post on this board. I have hypersomnia and have been prescribed provigil (costs an arm and a leg) so I will order from outside USA. My question is: On other boards I read that combining use of ritalin with provigil helps others. Does anyone have experience combining these two?
I know that previous to provigil, ritalin was prescribed for hypersomnia.

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#778939 - 10/05/08 02:58 AM Re: Ritalin - Methylphenidate [Re: trex9]
PrivateRealm Offline
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Registered: 03/18/03
Posts: 2568
Loc: In my realm, I'm QUEEN
That sounds dangerous at best.
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"A person's true identity is rarely apparent in the life that they lead."

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#780676 - 10/07/08 05:51 PM Re: Ritalin - Methylphenidate [Re: PrivateRealm]
trex9 Offline
Stranger

Registered: 09/06/08
Posts: 12
Loc: New Mexico, USA
Sorry, I wasn't precise in my question. What I have read was that some hypersomniacs alternated use of provigil
with use of ritalin as sometimes one gave better results
than the other.

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#782160 - 10/10/08 09:28 AM Re: Ritalin - Methylphenidate [Re: Melody]
toddz Offline
Member

Registered: 02/17/08
Posts: 113
id read some studies of using a small dose of ritalin with antidepressants in the elderly and with treatment resistent depression. has anyone here had any experience combining the two. id wondered if this combo might help my depression.

speaking of self medication, ive taken to having to go this route due to the [censored] poor quality of docs i encountered at the va hospitals. i had one old fool that wouldnt ever take me off celexa, like it was the single antidepressant available. all he would do is up my dose. i had another say he couldnt do anything more for me. and yet there were other meds and combinations not tried. i asked another shrink, could i be bipolar, and her answer, "could be". but nothing was ever done to determine if i was or not. so i understand the reasons pple will say its stoopid. on the other hand its stoopid to keep going to doctors that could care less about treating ones illnesses. and that seems to be most of them, imo. my va visits only added to my depression and anxiety issues. as i am a service connected disabled vet, i dont have the funds to go downtown and keep trying till i find one with both a brain and a heart.


Edited by toddz (10/10/08 09:30 AM)

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#782249 - 10/10/08 12:03 PM Re: Ritalin - Methylphenidate [Re: toddz]
jennygirl Offline
Member

Registered: 01/30/07
Posts: 184
Loc: N.E. USA
ok, this might be a dumb newbie question so i apologize in advance if i make anyone's eyes roll because of my ignorance in this regard ... but ...

is Ritalin (methylphenidate) really a true amphetamine? some sources say it is, some say it isn't, yet other's say it kinda is but its in a class of unusual types of amphetamines.

i even had someone at the club (claiming to be an authority on the subject but in all likelyhood just trying to impress me to pick me up) tell me that ritalin and ecstasy (ie methylenedioxy-methamphetamine aka MDMA) are almost exactly the same thing. found this hard to believe since i have experienced both and found them absolutely nothing alike whatsoever subjectively, except perhaps for the fact they both give me lots of energy.

thoughts? not asking to talk about illegal drugs here, just curious what chemical class ritalin actually belongs to.

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#782386 - 10/10/08 04:25 PM Re: Ritalin - Methylphenidate [Re: jennygirl]
nephro Offline
GRAND Pooh-Bah

Registered: 09/04/06
Posts: 9707
Loc: NOT 40!
It is related to the amphetamines, but isn't one.

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#782550 - 10/10/08 10:17 PM Re: Ritalin - Methylphenidate [Re: nephro]
jennygirl Offline
Member

Registered: 01/30/07
Posts: 184
Loc: N.E. USA
if not an amphetamine what is it then? an unclassified phenethylamine? are there any chemicals that are similar to methylphenidate in receptor affinity?

google search says it hits the dopamine, norepinephrine, and both 5HT1A and 5HT2B serotonin receptors. i realize alot of db'ers probably know this already like basic i just grabbed it off the net for your convenience and those reading who dont know.

thanks,
-Jenny

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#782808 - 10/11/08 12:54 PM Re: Ritalin - Methylphenidate [Re: jennygirl]
martind Offline
GRAND Pooh-Bah

Registered: 05/01/08
Posts: 1861
 Originally Posted By: jennygirl
if not an amphetamine what is it then? an unclassified phenethylamine? are there any chemicals that are similar to methylphenidate in receptor affinity?

google search says it hits the dopamine, norepinephrine, and both 5HT1A and 5HT2B serotonin receptors. i realize alot of db'ers probably know this already like basic i just grabbed it off the net for your convenience and those reading who dont know.

thanks,
-Jenny


It is simply a CNS stimulant just like caffeine or amphetamines. An "amphetamine-like" substance.
Obviously stronger than caffeine and somewhat weaker than dextroamphetamine.
Beyond that, the description morphs into medicalese best left to psychiatry/pharmacology forums I think.

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#783232 - 10/12/08 08:55 AM Re: Ritalin - Methylphenidate [Re: martind]
jennygirl Offline
Member

Registered: 01/30/07
Posts: 184
Loc: N.E. USA
thanks martind, that does make since. and your right that its kinda an esoteric issue perhaps discussed elsewhere, i was just interested upon learning about how its a stimulant with serotonin receptor affinity, and was wondering if there were any stimulants that had similar properties. i know some of the club drugs do but i was wondering about prescription meds.

bye

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#794436 - 10/29/08 10:57 PM Re: Ritalin - Methylphenidate [Re: OldandWorn]
jedbu346 Offline
Banned: Shill
Stranger

Registered: 10/17/08
Posts: 3
This forum is not to discuss suppliers. This thread is to discuss Ritalin - Methylphenidate and not the companies offering it.

Thanks for your support


Edited by Melody (10/30/08 04:41 AM)

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#811495 - 12/06/08 10:08 AM Re: Ritilan---Methylphenidate [Re: RZeta]
Ludes_Vet Offline
Board Addict

Registered: 11/29/04
Posts: 302
Loc: Southeastern U.S.
Hi RZeta,
Regarding your post on April 21, 2005, I agree with several points you made about Ritalin, and, Adderall.
You were right on the money, politically correct, about
Shire US (formerly Richwood Pharmaceutical Company, Inc.,
Florence, Kentucky, who "reinvented" Adderall, from the original patent holder of "Obetrol" (Obetrol Pharmaceuticals
Brooklyn, NY), as you correctly stated, the patent had ran
out on "Obetrol", and to make some formulation changes, the
motive was to make money, and yes, in 1994 Adderall took off like a rocket! (as you stated) The original formula for Obetrol also contained 4 different versions, of a Schedule II stimulant, (one ten (10 mg.) tablet contained the following: 2.5 mg. methamphetamine saccharate, 2.5 mg. of methamphetamine hydrochloride, 2.5 mg. of amphetamine sulfate, 2.5 mg. of dextroamphetamine sulfate. Obetrol 20
mg. (twenty milligrams) contained twice the potency. With
the "new formulation of Adderall" one ten milligram tablet contains: 2.5 mg. dextroamphetamine saccharate, 2.5 mg. of amphetamine aspartate, 2.5 mg. of dextroamphetamine sulfate, 2.5 mg. of amphetamine sulfate. I started out on Ritalin as well, (14 yrs ago), then, 11 years ago, switched to 15 mg. of Dexedrine Spansules, with Adderall immediate release tablets, as a late afternoon booster. I have now mostly abandoned Adderall, and like you, use the generic dextroamphetamine sustained release versions, (Barr) to save money, as the Dexedrine brand name was so much more expensive. It is interesing to note the history of Ciba
(who held the original patent to Ritalin) immediate release of methyphenidate, and the "Ritalin SR", as it has grown with "more improved versions of the sustained release methyphedidate" with the now "Ritalin LA capsules" in addition, for 3 versions of Ritalin from Novartis, (formerly Ciba) and the newer competitor, McNeil Pharma, with their version of methyphenidate "Concerta" (all extended release formulations), as the sustained release versions of Ritalin (methyphenidate) are geared especially for children and adolescents, who truly do have a balancing act with the up's and down's of the original formulation immediate release Ritalin, as I experienced a "crash" myself, as a middle-aged adult, about 3 times a day, thus I immediately discovered the need for a pocket "Pill Traveler" to carry on me 24/7 to have access to the stimulant "when I ran out of gas" (a more daunting task for a youngster). The original brand Ritalin or Mylan Generic, just didn't last but about 2 1/2 to 3 hrs max for me. I would go back to it, but only as a last resort, if the dextro isomer of the compound of d,l-amphetamine sulfate would be removed from the marketplace. One never knows in this changing world, as Smith-Kline, the patent holder of Dexedrine Spansule, has already removed their "gold standard" sustained release patented "Benzedrine" from the marketplace (within the past ten years) after being around approximately forty (40 yrs)! I have tried to abide by the Rules and not mention any IOP, NRPO, or ROP "suppliers", just the US based manufacturer's and a bit of history. Source: PDR's 1968, 1978, 1980, 1986, 1995, 2007. along with my personal history using prescription Ritalin vs. other prescription Schedule II meds for my A.D.D. diagnosis.
Addressing "ToddZ" 10/10/08.....yes my psychiatrist had me on Ritalin 3 x 10 mg. every 4 hrs, plus, Norpramin (desipramine HCI) for one year (1996) due to a dual diagnosis of ADD and Dysthymia (low grade persistent depression) and to try to counter-balance the up & down mood swings I was experiencing at the time.


Edited by Ludes_Vet (12/06/08 10:32 AM)

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#827062 - 01/09/09 03:29 PM Re: Ritilan---Methylphenidate [Re: Ludes_Vet]
trex9 Offline
Stranger

Registered: 09/06/08
Posts: 12
Loc: New Mexico, USA
LudesVet, thanks for the informative explanation of the many faces of ritalin. I just read and absorbed it.

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#926324 - 09/06/09 10:41 AM Re: Ritilan---Methylphenidate [Re: Ludes_Vet]
Myrtille Offline
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Registered: 09/06/09
Posts: 7
Loc: REUNION (france)
XXX OFF TOPIC DELETED XX


Edited by Melody (10/27/09 08:44 AM)

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#926408 - 09/06/09 03:30 PM Re: Ritilan---Methylphenidate [Re: Myrtille]
Talakrass Offline
Member

Registered: 09/17/08
Posts: 110
Loc: Texas
"Methylphenidate is a chain substituted amphetamine.[95] Similar to amphetamines and cocaine a key target of methylphenidate is the dopamine transporter (DAT).[96] Although methylphenidate is an amphetamine derivative subtle differences exist in its pharmacology; amphetamine works as a dopamine transport substrate where as methylphenidate works as a dopamine transport blocker.[95] Methylphenidate is most active at modulating levels of dopamine and to a lesser extent noradrenaline.[97]" - pulled off wikipedia

Traditionally, I believe methylphenidate has been used to treat primarily ADHD whereas amphetamines (adderall) have been prescribed to treat primarily but not exclusively ADD, which is different. I think its now known as ADHD-PI (Primarily Inattentiveness)
_________________________
Live well...do well...be well!

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#926422 - 09/06/09 04:00 PM Re: Ritilan---Methylphenidate [Re: Myrtille]
nephro Offline
GRAND Pooh-Bah

Registered: 09/04/06
Posts: 9707
Loc: NOT 40!
XXX OFF TOPIC DELETED XXX


Edited by Melody (10/27/09 08:42 AM)

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#926465 - 09/06/09 06:46 PM Re: Ritilan---Methylphenidate [Re: Myrtille]
pillar Offline
GRAND Pooh-Bah

Registered: 11/07/06
Posts: 1908
Loc: The Doors of Perception
REMEMBER THAT THIS THREAD IS TO DISCUSS RITALIN!!!!!!!!

THANKS


Edited by Melody (10/27/09 08:40 AM)

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#926516 - 09/06/09 09:24 PM Re: Ritilan---Methylphenidate [Re: nephro]
meonlyits Offline
Old Hand

Registered: 08/23/09
Posts: 427
XXX OFF TOPIC DELETED XXX


Edited by Melody (10/27/09 08:39 AM)

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#939198 - 10/05/09 01:51 AM Re: Ritilan---Methylphenidate [Re: nephro]
FattyAddy Offline
Banned. Mentioning his other account was sold to a shill. Foolish troll!
Journeyman

Registered: 10/04/09
Posts: 54
Loc: milwaukee
xxx off topic deleted xxx


Edited by Melody (10/27/09 08:34 AM)

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#940652 - 10/07/09 04:23 PM Re: Ritilan---Methylphenidate [Re: FattyAddy]
PLUMBOY Offline
Journeyman

Registered: 08/12/09
Posts: 91
This forum is not to discuss suppliers. This thread is to discuss Ritilan and not the companies offering it.

Thanks for your support


Edited by Melody (10/27/09 08:35 AM)

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#943238 - 10/13/09 04:50 PM Re: Ritilan---Methylphenidate [Re: PLUMBOY]
SuSu Offline
Stranger

Registered: 10/03/09
Posts: 1
This forum is not to discuss suppliers. This thread is to discuss Ritilan and not the companies offering it.

Thanks for your support


Edited by Melody (10/27/09 08:35 AM)

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#943961 - 10/14/09 11:32 PM Re: Ritilan---Methylphenidate [Re: jbol]
bb5 Offline
Stranger

Registered: 05/27/05
Posts: 13
Loc: USA
This forum is not to discuss suppliers. This thread is to discuss Ritilan and not the companies offering it.

Thanks for your support


Edited by Melody (10/27/09 08:37 AM)

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#945717 - 10/18/09 11:44 AM Re: Ritilan---Methylphenidate [Re: bb5]
inocula Offline
Newbie

Registered: 10/06/09
Posts: 36
Loc: EU
This forum is not to discuss suppliers. This thread is to discuss Ritilan and not the companies offering it.

PLEASE STAY ON TOPIC!!!!!!!!!!!!!!!!!

Thanks for your support



Edited by Melody (10/27/09 08:37 AM)

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