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#768315 - 09/18/08 06:15 PM Re: Ultram - Tramadol ***** [Re: daddyd]
nephro Offline
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 Originally Posted By: daddyd

Ive tried Bupe 0.2 x 2 and they seem to work, would these be any less damaging or difficult to get off while I work through the last stage of this problem.



I would say you're safer with using 0.2mg or 0.4mg buprenorphine than high Tramadol and co-codamol doses. It may well be easier to withdraw from as well, as people have reported success jumping off low buprenorphine doses, whereas withdrawing from Tramadol almost always seems to pose difficulties.

If people are taking >8mg buprenorphine in the form of Suboxone/Subutex per day for quite long periods, Temgesic doses shouldn't harm your body much at all. And being sublingual, they can be tapered easily.

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#768321 - 09/18/08 06:43 PM Re: Ultram - Tramadol [Re: nephro]
daddyd Offline
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Registered: 08/01/08
Posts: 390
Loc: UK
 Originally Posted By: nephro
 Originally Posted By: daddyd

Ive tried Bupe 0.2 x 2 and they seem to work, would these be any less damaging or difficult to get off while I work through the last stage of this problem.



I would say you're safer with using 0.2mg or 0.4mg buprenorphine than high Tramadol and co-codamol doses. It may well be easier to withdraw from as well, as people have reported success jumping off low buprenorphine doses, whereas withdrawing from Tramadol almost always seems to pose difficulties.

If people are taking >8mg buprenorphine in the form of Suboxone/Subutex per day for quite long periods, Temgesic doses shouldn't harm your body much at all. And being sublingual, they can be tapered easily.


Thanks a ton for that mate, it looks like Im going to have to start looking for a reliable bupre source... let the search begin...
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#768417 - 09/18/08 10:11 PM Re: Ultram - Tramadol [Re: Melody]
grey12 Offline
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i have been having sever sinus headaches with nausea after taking Tramadol the next day..but i have these headaches regularly.plus i notice that your body temp rises alot on Tramadol..also when i pee i notice a really powerfull stream

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#768478 - 09/19/08 02:32 AM Re: Ultram - Tramadol [Re: grey12]
SoHoTribeca Offline

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I'm not surprised at all about that. I had a little taste of that medication and the headaches, illness, wretchedness was horrible. I immediately reordered fioricet. I have the demon bottle in a drawer, because I'm a pack rat. Sometimes a friend has a headache or pain with nothing to take, and there's no point in having it go to waste.
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#879165 - 04/22/09 03:24 PM Re: Ultram - Tramadol [Re: SoHoTribeca]
j123456k Offline
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Registered: 09/27/06
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I have tried Tramadol and do take SSRI's as well. Have talked with various pharmacists and doctors and as long as you keep your Tramadol use moderate and short term, Serotonin Syndrome is no worry at all.

I find that Tramadol does not work on pain as well as the opiates, but does sort of make me feel good.

I have had some skin irritations, but do not know if Tramadol had anything to do with it.

Have anyone had an issue with skin rash/irritation/itching?

Thanks,

Jeff

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#884424 - 05/07/09 07:11 AM Re: Ultram - Tramadol [Re: Melody]
mskatt Offline
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Registered: 12/31/06
Posts: 79
Loc: Central Florida
I saw my PCM yesterday and she gave me 50 mg Tramadol to take up to 8 a day for herniated disks. I actually had been taking hydro from a F2F pm doc for it but the ones I got this last month were old, etc. brand did not work (vintage). She also upped my Zoloft from 100mg daily to 150mg daily and warned me about serotonin syndrome. The pharmacist also warned me so I am a little scared to take both. Any input? I took 2 50 mg Tramadol last night and had taken the 100mg zoloft in the morning and nothing happened. Thx in advance for any input \:\)
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#917061 - 08/11/09 05:33 PM Re: Ultram - Tramadol [Re: mskatt]
Code21 Offline
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Okay so now I'm worried as hell. I was prescribed Tramadol today, and I take 450mg of Effexor, 300mg of Trazodone and 2mg of Clonazepam. Sooooo... should I not take the Tramadol at all? Wonder what the pharmacist is going to say to my husband when he picks it up. frown Great.
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#917072 - 08/11/09 05:59 PM Re: Ultram - Tramadol [Re: Code21]
nephro Offline
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I really think it would be very risky taking any amount of Tramadol with those antidepressants.

Although trazodone and venlafaxine have been used together quite a lot, it isn't without risk; you may find this interesting:

http://ajp.psychiatryonline.org/cgi/content/full/158/12/2088

Are all three drugs prescribed by the same doctor?

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#917094 - 08/11/09 07:08 PM Re: Ultram - Tramadol [Re: nephro]
Code21 Offline
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Yes, all three drugs are prescribed by the same doctor, my psychiatrist. I have a TERRIBLE sleep disorder and terrible anxiety. Thanks for replying nephro.

I did take one and while it has quelled my pain, it has made me sweat profusely and gave me a headache. frown
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#917095 - 08/11/09 07:12 PM Re: Ultram - Tramadol [Re: Code21]
Code21 Offline
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I also take 10mg of Ambien at night - same doctor as well.

Now I'm kinda worried. I need to do some more reading about serotonin syndrome and seizures to make sure I know what to look out for.
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#917098 - 08/11/09 07:23 PM Re: Ultram - Tramadol [Re: nephro]
sonik Offline
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Nephro

Juat read your link and it scared me a little as I have some of the symptoms of the syndrome described. I take 150mg-200mg of trama ( single dose )in the morning and up to 50mg of hyro ( in 10/325 incements ) 4-6 our later, over a time period of about 3-4 hrs ( 25mg loading dose titration in 10mg increments. I shake, and have what I call the "twitches" usually in the morning after the trama.Speach is also a problem too sometimes. Its like I cant get the words out of my mouth correctly. I know you are very knowledgable. Could these issues be EXCESSIVE seritonin? Could I be at risk here? I take no other meds besides these. NO ssri, snri, state of ri ( sorry currrent resist smile )


Edited by sonik (08/11/09 07:25 PM)
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#917099 - 08/11/09 07:23 PM Re: Ultram - Tramadol [Re: Code21]
nephro Offline
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http://en.wikipedia.org/wiki/Serotonin_syndrome#Signs_and_symptoms

This Wiki article uses our own Chemsynth's paper, "The Serotonin Syndrome" as references, so it's probably accurate.

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#917100 - 08/11/09 07:25 PM Re: Ultram - Tramadol [Re: nephro]
Code21 Offline
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THANK YOU!!!!! &#9829;
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#917101 - 08/11/09 07:27 PM Re: Ultram - Tramadol [Re: sonik]
nephro Offline
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Sonik, probably yes. Chemsynth is the expert on this condition; I am certainly not. I will send him a PM though directing him here. Of course you should see your doctor, but then it's a question of if he knows anything about it; apparently a lot of docs don't.

I've also e-mailed him. This is out of my league and needs a specialist toxicologist.


Edited by nephro (08/11/09 07:33 PM)

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#917108 - 08/11/09 07:52 PM Re: Ultram - Tramadol [Re: nephro]
sonik Offline
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Thanks nephro. This has been going on for years so i dont think i am in any immediate danger per se. I am concerned with the long term effects on my CNS and Brain.

BTW.Probably YES to what? Excessive seritonin or me being st risk. With regards to telling my doc. I would love to, but then I would be taken off of what works for pain contol for me. The dosages I take have been developed over YEARS of taking these meds 5 yrs for the trama 10 for the hydro.

I appreciate yourhelp and look forward to hearing from Chemsynth.

Sonik
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#917109 - 08/11/09 07:54 PM Re: Ultram - Tramadol [Re: nephro]
chemsynth Offline
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couple of things:

1. seizures are an adverse effect of Tramadol, but they are not serotonergic in origin. they have a totally different cause/treatment

2. serotonin is one of teh neurotransmitters that is responsible for regulating movement: too much serotonin can lead to too much movement. a common finding in someone with serotonin syndrome is tremor/thumping in legs more so than arms, increased muscle tone/rigidity.

3. serotonin is one of the neurotransmitters that controls behavior. too much serotonin, too much....of you. patients are "hypomanic', meaning that they are a bit too loud, move to fast, a bit uncontrollable, etc, etc.

4. symptoms of serotonin syndrome arise within 24 or less (usually much less, like 6 hours) of starting a new medication.

the reality is that many people respond to these medications differently, so anyone who has any concerns should see their doctor or go to an ER.

and, just for nephro--no demerol!!

hope this helps,

chemsynth
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#917114 - 08/11/09 08:12 PM Re: Ultram - Tramadol [Re: chemsynth]
sonik Offline
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Originally Posted By: chemsynth
couple of things:

1. seizures are an adverse effect of Tramadol, but they are not serotonergic in origin. they have a totally different cause/treatment

2. serotonin is one of teh neurotransmitters that is responsible for regulating movement: too much serotonin can lead to too much movement. a common finding in someone with serotonin syndrome is tremor/thumping in legs more so than arms, increased muscle tone/rigidity.

3. serotonin is one of the neurotransmitters that controls behavior. too much serotonin, too much....of you. patients are "hypomanic', meaning that they are a bit too loud, move to fast, a bit uncontrollable, etc, etc.

4. symptoms of serotonin syndrome arise within 24 or less (usually much less, like 6 hours) of starting a new medication.

the reality is that many people respond to these medications differently, so anyone who has any concerns should see their doctor or go to an ER.

and, just for nephro--no demerol!!

hope this helps,

chemsynth


Thanks Chem. I think I am probably fine, based on your above info. I was the OP that asked Nephro about SS Are there any long term effects linked to excessive or high levels of serotonin; levels that would be provided by the dosages and medications described in my previous posts?
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#917121 - 08/11/09 08:33 PM Re: Ultram - Tramadol [Re: sonik]
Code21 Offline
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Thank you chemsynth!!!
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#917124 - 08/11/09 08:43 PM Re: Ultram - Tramadol [Re: sonik]
chemsynth Offline
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the honest answer is that nobody knows. for example, up to 85% of docs don't even know about SS as a clinical entity. unfortunately, it is awfully hard to determine what the long-term effects of a clinical entity are that docs are unaware of, if you know what i mean.

chemsynth
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#917128 - 08/11/09 08:46 PM Re: Ultram - Tramadol [Re: chemsynth]
nephro Offline
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Thanks for responding so quickly Chem.

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#917137 - 08/11/09 09:16 PM Re: Ultram - Tramadol [Re: nephro]
sonik Offline
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Yes. Thank you Chem for the quick response. I also read your Wiki article. Good info.
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#930776 - 09/16/09 08:32 PM Re: Ultram - Tramadol [Re: sonik]
Administrator Offline
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From Wikipedia http://en.wikipedia.org/wiki/Tramadol

Quote:
Grünenthal, which still owns the patent to Tramadol, has cross-licensed the agent to pharmaceutical companies internationally. Thus, Tramadol is marketed under many trade names around the world, including:

Acugesic (in Malaysia and Singapore)
Adolonta (in Spain)
Algifeno (in Bolivia)
Anadol (in Bangladesh and Thailand)
Boldol (in Bosnia and Herzegovina)
Calmador (in Argentina)
Campex (in Pakistan)
Contramal (in India, Italy, and Turkey)
Crispin
Dolcet (in the Philippines)
Dolol (in Denmark)
Dolzam (in Belgium and Luxembourg)
Dromadol (in the United Kingdom)
Exopen (in South Korea)
Ixprim (in France and Ireland)
Lumidol (in Bosnia and Herzegowina and Croatia)
Mabron (in Bahrain, Bangladesh, Bulgaria, Czech Republic, Estonia, Iraq, Jordan, Latvia, Lithuania, Malaysia, Oman, Romania, Singapore, Slovakia, Sri Lanka, Sudan, and Yemen)
Mandolgin (in Denmark)
Mandolgine
Mosepan
Matrix (combined with paracetamol) (in Honduras and Guatemala)
Nobligan (in Argentina, Denmark, Iceland, Mexico, Norway, Portugal, and Sweden)
Osteodol (in India)
Poltram (in Poland)
Ralivia (in Canada)
Ryzolt (in the United States)
Sintradon (in Serbia)
Siverol (in the Philippines)
Tandol (in South Korea)
Tiparol (in Sweden)
Tonoflex (in Pakistan)
Toplagic
Tradol (in Bangladesh, Ireland, Mexico, Singapore, and Venezuela)
Tradolan (in Austria, Denmark, Finland, Iceland, Romania, and Sweden)
Tradonal (in Belgium, Indonesia, Italy, Luxembourg, the Netherlands, the Philippines, Spain, and Switzerland)
Tralgit (in the Czech Republic, Georgia, Romania, and Slovakia)
Tralodie (in Italy)
Tramacet (combined with paracetamol) (in Canada and Costa Rica)
Tramacip (in India)
Tramadex (in Israel)
Tramadin (in Finland)
Tramadol (in Chile and Romania)
Tramadol Stada (in Sweden)
Tramadolor (in Austria, Estonia, Germany, Hungary, Latvia, Lithuania, Luxembourg, and Romania)
Tramagetic (in Norway)
Tramagit (in Romania)
Tramahexal (in Australia)
Tramake (in the United Kingdom)
Trama-Klosidol (in Argentina)
Tramal (in the Netherlands, Finland, Croatia, Slovenia, Brazil, Chile, Romania, Australia, New Zealand, Germany, and Switzerland)
Tramalgic (in Hungary)
Tramal Gotas (in Ecuador)
Tramazac (in India, Myanmar, and Sri Lanka)
Tramed
Tramedo (in Australia)
Tramoda (in Thailand)
Tramundal (in Austria)
Tridol (in South Korea)
Tridural (in Canada)
Trodon (in Serbia)
Ultracet (combined with paracetamol)
Ultradol
Ultram and Ultram ER (in the United States)
Ultramed (combined with paracetamol) (in India)
Veldrol (in Mexico)
Zafin (combined with paracetamol) (in Chile)
Zaldiar (combined with paracetamol) (in Spain, Croatia, Poland, Russia, and Chile)
Zaledor (combined with paracetamol) (in Chile)
Zamadol (in the United Kingdom)
Zamudol (in France)
Zodol (in Chile, Ecuador, and Peru)
Zydol (in the United Kingdom, Ireland and Australia)
Zytram (in Canada, Iceland, New Zealand, and Spain)
Zytrim (in Spain)

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#931020 - 09/17/09 02:37 PM Re: Ultram - Tramadol [Re: Administrator]
pragmatic Offline
Member

Registered: 08/16/07
Posts: 184
Question: can a state black ball you for using Hyrocodone. I tried to get it from my Dr. and he said that his hospital does not issue that med on a monthly basis. So I am still stuck with Tramadol?

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#931270 - 09/18/09 06:08 AM Re: Ultram - Tramadol [Re: pragmatic]
pragmatic Offline
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Registered: 08/16/07
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I hope people will come and talk more about thsi drug because it is important. I just hope people can find it now

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#931406 - 09/18/09 12:41 PM Re: Ultram - Tramadol [Re: pragmatic]
pragmatic Offline
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Registered: 08/16/07
Posts: 184
I also don't like that fact thatyou cannot find this most importent topic.
Aso I need thsi qestion answered emediately.

Question: can a state black ball you for using Hyrocodone. I tried to get it from my Dr. and he said that his hospital does not issue that med on a monthly basis. So I am still stuck with Tramadol?

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#931427 - 09/18/09 01:22 PM Re: Ultram - Tramadol [Re: pragmatic]
martind Offline
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No, a state cannot "blackball" you for using hydrocodone.


Edited by martind (09/18/09 01:22 PM)

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#931441 - 09/18/09 01:37 PM Re: Ultram - Tramadol [Re: pragmatic]
stevo1 Online   content
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Originally Posted By: pragmatic
I also don't like that fact thatyou cannot find this most importent topic.
Aso I need thsi qestion answered emediately.

Question: can a state black ball you for using Hyrocodone. I tried to get it from my Dr. and he said that his hospital does not issue that med on a monthly basis. So I am still stuck with Tramadol?


pragmatic
You can get Flagged!!..But more likely the Doc just Doesn't want to script Hydro!! So he told you a BS Story.
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