Dihydrocodeine (DHC) is a synthetic opioid analgesic developed in the early 1900s. Its structure and pharmacokinetics are similar to that of codeine and it is used for the treatment of postoperative pain, severe breathlessness or as an antitussive.

Dihydrocodeine is approximately twice as potent as codeine; take this into consideration while dosing dihydrocodeine.

has anyone sampled the dihydrocodeine descibed as "codesic" by an asian pharmacy or the "df-118s" offered by another asian pharmacy?
do any DHC experts reckon they are purely DHC or just codiene sulphate or even worse-a counterfeit product with not the true 30mgs dose?

I've had the Codesic a few times. I believe it's the real thing, same as Didor Continus or Contugesic except it's not the sustained release.

Yes, two 30 mg tablets seems the same as 1 chewed Didor Continus or Contugesic

What else is in the 30mg from "that" place? They weigh 300mg. What is the other 270mgs?

IT could be how they are disposing of the nuclear waste. I would test for radioactivity!! Actually it is what would be called an inert filler (usually plutonium).

Zip

you can not base stregth on weight. ie oc 80 mg they do not weigh 80 mgs.

Question for anyone who has taken DHC. I know it's like codiene, but how "Like" it is it? I ask, because I can take Hydro and Oxy and everything with no problem, but Codiene makes me itch like you wouldn't believe. I've never tried DHC, nor do I plan on it, but I was wondering in case I was ever in a situation that I found I had no choice but the DHC if I should take it or if it'd do the same thing to me as codeine. BTW, just a little tid bit of fun, you know the I before E rule, except after C and ....., well Codeine is one of a few limited words that doesn't follow that rule:)

not saying you can base strength on weigh just wonderign what the other 90 percent of the pill is.

If codeine makes you itch, DHC will do the same thing. All you have to do is take a antihistamine to stop the itch. I take one Benadryl and it stops any itch. Without it, the itching is unbearable.

codeine never makes me itch even at quite high dosage but DHC makes me scratch myself to shreds at minimum dosages. I need to take 25mg phenergan 3 times per day when taking DHC & even that doesnt prevent all the itchies; it just makes it a bit easier to avoid scratching myself till I bleed. It's the one side effect I cant stand.

Quote:

---

(snipped) .... codiene, but how "Like" it is it? I ask, because I can take Hydro and Oxy and everything with no problem, but Codiene makes me itch like you wouldn't believe.

---

I tried DHC a couple of times. It was terrible. It was a lot like withdrawl. It was similar to the time I was accidentally ( through ignorance) abusing oxycontin. I was very agititated and just felt awful. No other opiates do that to me. The pills are tiny white ovals, imprinted "DHC 60". Are these time release?? Any other thoughts? It would be nice to have these for a backup, but I don't even want to experiment again unless I have an understanding of what happened, and I am confident I have a way to manage things.

Contugesic isn't made anymore, it's been out of production since 2003. The only med that contains 60mg of time-released DHC now is Didor Continuus.

I would like to correct Toe's statement about the production of Dihydrocodeine.
In addition to the time released 60mg. tablets of Dihydrocodeine produced by Viatris in Spain, labeled as Didor Continus.
It is also available and being produced in South Africa by GlaxoSmithKline in 30mg. instant release tablets labeled as DF118.

Didor Continus is used to treat moderate to severe pain. Here are some experiences from people I found on a website. If anyone knows of a source please pass it on.

- On a recent trip to South Africa, I tried to lift a heavy suitcase and collapsed. The hotel doctor was summoned and prescribed 60MG of Dihydrocodeine. I can state without equivocation that this drug is extremely powerful; within a half hour of taking 60 mg, I was totally free of pain and felt a sense of mild euphoria. I normaly take OxyContin 60MG twice daily. As everybody knows, OxyContin is a very powerful drug. I have found that Dihydrocodeine works just as well as OxyContin. This drug has satisfied my pain relief needs on those occasions that I have not been able to obtain OxyContin.

- It works pretty well and is kinda like hydro. It works great.

- Basically, dihydrocodeine is comparable to our hydrocodone or vicodin except that it contains no tylenol, which is great for those of us who need the medication in higher doses. Save your livers, try to order the dihydrocodeine. It is also about 2.5 times more potent than regular codeine phosphate because its molecular structure allows the drug to be converted quicker in the brain tomorphine and does not completely get absorbed in the liver. Anyway, dihydrocodeine is good stuff, but alot stronger than regular codeine.

- On a personal level, I found Dihydrocodeine a great help in managing my sciatic pain. I took it for about eight weeks, until I was admitted to hospital where a wonderful orthopedic surgeon put my back right for me.

- In my opinion this is a fantastic painkiller with few side effects, the worst of which can be avoided by a good doctor. As for the constipation, there is a little secret cure, and it's good old fruit and vege, and lots of it! A little Aloevera (a medicinal cacti used for the last 4000yrs) extract also does wonders, you can by it in pill or juice form and can find it in your local health food store.

- I just started taking Dihydrocodeine about two months ago to treat chronic neck pain. Vicodin was not working, so I guess this is the next step up. I only use it when the pain gets really bad, which is every couple of days or so. As far as addiction goes, I would have to say that it is not addictive, as I can take it for two days then go off it for three or four days with no adverse effects. I haven't developed a tolerance to it at all either. I like this drug because it eliminates my pain, but doesn't make me totally non-functional like Vicodin does. You need to stay hydrated, so drink plenty of water or Gatorade. The other thing to watch is constipation.

- Dihydrocodeine is not 2nd only to morphine in potency. Two other opiates, Oxycodone and Hydrocodone, are approximately three times as potent as Dihydrocodeine. Oxycodone is used in Oxycontin and in Percocet, while Hydrocodone is used in a myriad of products - most common of them being Vicodin and Lortab. Dihydrocodeine is an excellent drug, especially in that it is not as addictive as these others, but as one ""goes up the ladder"" one would use Hydrocodone (after Dihydrocodeine), then Oxycodone, and then morphine. Note that there are others even more potent than morphine. For example,Hydromorphone is approximately 10 times as potent as morphine.

Ok, please check my math. Something doesn't seem right.

mg/mg, hydro is 6 times as potent as codeine (phosphate). DHC is twice as potent as codeine. Therefore, hydro is 3 times as potent as DHC. If I am taking 40mg of hydro per day and want to change to DHC, I would have to take 120mg per day. I have the "continuous" 60mg DHC pills, so I would take 2 of these per day to get the same effect as 4 10mg hydros per day. Right?

I don't know how to tell you to calculate the dosage for type of dhc you are taking JethroBodine as I have never took it .I have been getting the 30mg codesic [dhc] made in Malaysia .To me they are almost as powerful as 10mg hydro not quite the same effect but good .They are only $1.25 a piece from the IOP I have been getting them from .It beats ordering from the domestic NROP,s that charge $3 to $4 a piece for the 10mg hydro and seem to go out of business every other week now .I prefer the domestic hydro but have not been able to get a order since August.I think I will just keep getting the dhc until I come up with a better alternative.I guess my post is slightly off topic but that is my opinion .


harley88

I have tried both Didor Continus 60mg. and Codesic 30mg. I have yet to try DF118. In my opinion, 60mg of DHC is comparable to 5mg. Hydrocodone. But I would like to add that DHC seems to stay in your system much longer than Hydro. All I hear is good things about Dihydrocodeine, and how effective it is for pain relief. I have yet to hear one negative thing about it. The thing I would like to know is why is it not prescribed more often, and made available in more than the just a few low dosage medications. Could someone tell me the names of the domestic versions of DHC medications available, and what the different stengths are?

I am answering my own question. After doing a little searching I found three different medications containing Dihydrocodeine available locally. They are as Synalgos-DC, Panlor, and DHC plus. They all contain 16mg. Dihydrocodeine, 356.4mg. Aspirin and 30mg. Caffeine. I do not understand why they are not available in a higher DHC count.

back to the topic to what else is in those 30mg DHC tabs. I had been taking 6 per day for a couple of months & got a routine liver function test that showed almost all levels at 3 or 4 times normal range. My doc said its not unusual to see levels like that in response to some medications. I am on other meds that Ive been on for years without anything like this showing up. The only new med in the mix was the dhc.

Im making the assumption that this med at that dose for that long was battering my liver. I was scared sh|tless when I got those results & I dont know what to do.
Are the Didor Continuus available from an IOP? If so please reply or pm me which one it is. Im going to save the 30mg tabs for emergency only use from now on.

Rara: Could you please tell us where the DHC's you are talking about are from ?

DHC like codeine, should in a short while break down to morphine in the blood and little more that matters. Morphine in the blood is definately addicting, although if you keep doses low, problems arise far less so. I remember someone before saying they thought something is being added to the DHC from the Phillipines. I am not convinced that there is anything added to the those pills. DHC has subjective effects that are different from codeine which some people prefer and others do not. Supposedly DHC is less foggy and less sedative than regular codeine, so that description of DHC sort of describes hydro to me. Of course metabolisms differ and people respond differently toevery medication. Some people say DHCs strength seems on par with codeine others say 1.5 times stronger and above I read twice as strong. I think the difference in perspective depends on what ails you. If someone measures their medicine by how happy they become from the drug, then a very different viewpoint will be held than from someone who measures or compares a medicine's pain killing relief. Some physical body ailments might be better served by one over the other, so the strength would vary by condition.

If someone has a lot of experience with true, well labelled DHC from the US or Europe, and they have also used the unlabeled, no brand Philippine variety, I'd like to know how do they compare?

If you are comparing the Liver damage of DHC with Hydrocodone, I may be wrong, as I am no physician, but usually the liver dammage associated with Hydrocodone is from the APAP that is in them (Acetaminophen=APAP)
example: 10/500 = 10mg Hydrocodone & 500mg APAP. Or 10/325 = 10mg Hydrocodone & 325 APAP. I am aware that most of you guys know this, but I am sure that a few of you don't. I hope I have helped at least one person, that would make it worth the time I have spent. Thanks for a great informative forum. You guys have saved me hours of research at times. Just trying to give a little back

The Dihydrocodeine from the Philippines is made by:

Pharmaniaga Manufacturing Berhad
(formely known as Raza Manufacturing Berhad)
11A,Jalan P/1, Kawasan Perusahaan Bangi,
43650 Bandar Baru Bangi, Selangor Darul Ehsan,
Malaysia

COMPOSITITION
Each tablet contains Dihydrocodeine Tartrate 30 mg.
(Nothing else is mentioned)

I really miss Contugesic. I routinely substituted it for the hydrocodone I was taking, to give my liver a break from all that APAP. While it wasn't as good as hydro when it came to giving me energy and a sense of well-being, it was really almost as effective for my pain. But I think what I liked the most was the extended-relief factor. It would easily last 6-8 hours.

It's my understanding that Didor Continuus is the same thing. Am I correct?

Thank you all for the information.

Didor Continuus is another brand name for 60mg time-released DHC, yes. The reason I posted is because brand name Contugesic isn't being made. You can still get DHC.

I couldn't find this product listed on their website. Do you need to request it. Feel free to PM me. Thanks

There is an immense amount of information on DB. For a subject like DHC, you'll get far more info. from the search function than you will from who ever just happens to reply today. And BTW, DHC is very scarce. You'll find the details already posted. And.... wecome to DB!

I appreciate what you're saying about using the search function. I just tried it under both dihydrocodeine and DHC and only this and one other thread came up.

I'm sure there's old posts, but with this topic, the info has to be current or it's probably useless.

Did I do it wrong or something?

no you did not do anything wrong.

what makes some members so short are a newbie with a few posts or non will make there first post"where can i get vicodin" or 'what is a good source of oxy"

alot of questions can be answered just by looking with the serching. it is just the repeating questions over and over again that make veteran members tired of retyping the same thing over and over again. because people are getting there post prevligase and asking quetions without resercing simple questions first.

all new members can PM people. I always answere a pm. especially from a newbie with a legitimate question or just to help point them in the right direction

go back to the search function again, and set the time to 1 year instead of one week.

so does anyone know how well the panlor with 7.49 mg dhc works?

I can tell you that 7.49 mgs of DHC isn't much at all. I used to get 60mg Contugesics - which were a bit much, actually. I'm not sure what's up with Synalgos DC - that was a US-approved DHC-containing pain med. DHC can be bought OTC in the UK - or at least it could a few years ago. I always found DHC to be rather rough on the stomach and a bit "raw" - not nearly as refined as hydro, or even codeine phosphate. Just MHO. Good luck!

My experience ....a few years ago I was prescibed something called Panlor DC(I think that is dihy with tylenol and caffiene)..from what I remember they were red capsules.I had to take two of them for pain relief.They were not as strong as a hydro and the caffeine that was in it made me sick.
Since back then I haven't seen any at all or even heard of docs prescribing them around here.I do know a friend of mine gets a syrup that is called Panmist and it's suppose to have it in it(I don't know for sure tho)
Just my experience...
Kam

To answer a few questions that I know "a little about"-1) As far as having a small amount of chemicals(mg wise) in a larger pill, what you will find is that it is mostly what they call fillers(to make the pill bigger and look like its worth paying for) and binders(which are usually harmless starch based products that hold everything together). Have you ever "tried" to make a pill that looks legit. Trust me, its not as easy as it looks!!! Then especially with the generics you're going to have to include "coloring agents" to "mimick" the appearance of the actual pill color. Spectrophotometry is in itself an "enlightening" subject.(sorry, but I couldn't resist the pun) 2)If one were TRULY interested in the different strengths of various medications(i.e. legal over the counter pills then your best bet is to go to a VERY well stocked book store and purchase what is called the Physicians Desk Reference (PDR) which is the same book that doctors use when deciding which medication to prescribe to you depending upon your ailment. This book is legal to buy, at least in the United States. Also, just for your info, 1st and 2nd year students are basically the only ones that use this book although doctors keep them in their office. After a couple of years of medical practice one tends to use "fall back" medications which older doctors usually convince their younger protege's of why their own personal choice is usually the best. However, also included in the PDR is the molecular breakdown of the medication, what specific binders and fillers and whatever else may be in there is also included as well as the potency equivalent to I believe morphine. In other words it would tell you how effective Hydrocodone is compared to morphine and more importantly, HOW MUCH HYDROCODONE (mg) WOULD BE NEEDED TO EQUAL THE STANDARDIZED DOSAGE OF MORPHINE, usually given to rats. It also tells you what the average effective human dosage would be per Kg(Kilogram) and thus that is how they come up with either take every 4 or every 6 hours, depending upon body weight. It also tells you what the metabolites are as well as the "LD-50," which means given this much of the drug per Kg of body weight is what is needed for 50% of the test population to live and 50% of the population was given the "LD" or Lethal Dose....But what do I know, I just read it in the Enquirer somewhere because "Enquiring Minds want to Know!!!"

bushidodan

Look for synalgos DC. Dihydrocodeine aspirin and caffeine. Its still in production. But its old meaning came on market back in late 70s Drs were prescribing back then.They don't really prescribe it that much since hydros came on market. Back in those days you really didn't see alot of hydros only in old cough meds like citra forte syrup . Which is no longer on the market

At the ER last year when I had pleurisy I was given a script for Panlor SS ---supposedly double the strength about wht you talking about--it was DHC--good stuff too---I could type 100 WPM it seemed---cannot find online though, and not too many docs will write for it, that I know of.

yes.......and It gives my husband a boner for almost 4 minutes!!!!!!!!!!!!!!!11

I took this as a kid in a cough syrup I think and yes itchy itchy itchy!!!!!! Isn't the liquid similar to tussin hd?

If ANY drug makes you itch. Taking a antihistamine to offset the itch could be not only dangerous, but fatal if you continue taking the offending medication. It's called anaphylaxis. Beware

You made me laugh for the first time in quite awhile. The boner comment got me going. Not literally just in the spirit.

Love,
mike
psycho fo' da' Lawd

Not sure of the ration comparision to hydro, but I can say from past experience with Dihydrocodeine that is was more effective of a pain reliever than the hydro is/was. To bad Contugesic can't be found online anymore!!

I have been trying to find a dr to prescribe Panlor SS for quite a while because it works really well for me, better than hydro, and can't. Many Dr's don't know what it is. One ROP actually said "We can't write for oxycodone or any Schedule II narcotics". I said it's not Percodan, it's Panlor (dihydrocodeine). He didn't know what it was, said he'd never heard of it, and it's not in my 2007 med book either.

The analgesic activity of dihydrocodeine is roughly equal to that of codeine.

Yes, headaches are a funny one to deal with by narcotics, and can be a side-effect of the narcotic itself. Codeine is known for this.

I had ordered 30mg codeisan (codeine phosphate), but the headaches I got after the drug has worn off and especially the next day are horrible. I am not going to take the codiene phosphate anymore.

However, I have been using the DF118 (dihydrocodeine) and they work very well and seem to be a potentiator for hydrocodone. In addition, this may seem funny, but the DF118 induces a little diarrhea, which sort of offsets the constipation from the hydro. To me, the dihydro is way better than the codeine phosphate.

Bottom line, I get a better acting drug and do not have constipation either!! Not so bad. Does anyone know a good supplier for dihydrocodeine these days? I used U2RX for my last batch.

JM

You're not the first person to diarrhoea on DHC. The first time I heard of it, I thought the patient was mad, but it really does happen.

My doctor rx'd me panlor ss over a month and half ago when chatcp wasn't sending my meds so I would have something to help. He told me it was an 'experimental' drug he was trying on me that only 1 patient in his office was getting it for their backaches and headaches. I didn't know much about it at first and took one w/out eating oh I was sick! The pain left lol. Anyways, here is the link u can copy for your doctor if you still haven't gotten him/her to rx it for you....
Hope this helps!! I did find it works better than hydro, I don't know about the panlor DS now, but the SS one does. cali





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Ads by GooglePanlor SS
Generic Name: acetaminophen/caffeine/dihydrocodeine (a seat a meen O fen/ CA feen/ di hi dro CO deen)
Brand Names: Panlor DC, Panlor SS

What is acetaminophen/caffeine/dihydrocodeine?
Dihydrocodeine (related to codeine) is in a class of drugs called narcotic analgesics. It relieves pain.

Acetaminophen is a less potent pain reliever and a fever reducer. Acetaminophen increases the effects of dihydrocodeine.

Caffeine is believed to constrict dilated blood vessels that may contribute to tension headaches.

Acetaminophen/caffeine/dihydrocodeine is used to treat moderate-to-severe pain.

Acetaminophen/caffeine/dihydrocodeine may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about acetaminophen/caffeine/dihydrocodeine?
Avoid alcohol while taking acetaminophen/caffeine/dihydrocodeine. Alcohol can greatly increase drowsiness and dizziness caused by the medication which could be dangerous. Also, alcohol increases the risk of stomach bleeding when taking acetaminophen. Do not take more of this medication than is prescribed. If the pain is not being adequately treated, talk to your doctor.
Do not take other over-the-counter and prescription products that contain acetaminophen. Too much acetaminophen could be dangerous. Talk to your doctor or pharmacist before taking any over-the-counter preparations.

Drowsiness or dizziness caused by acetaminophen/caffeine/dihydrocodeine may be increased by other drugs such as antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Together, these medicines may cause dangerous sedation, possibly resulting in unconsciousness or death. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

Do not stop taking acetaminophen/caffeine/dihydrocodeine suddenly if you have been taking it continuously for more than 5 to 7 days. Stopping suddenly could cause withdrawal symptoms and make you very uncomfortable. Your doctor may want to gradually reduce the dose.

What should I discuss with my healthcare provider before taking acetaminophen/caffeine/dihydrocodeine?
Before taking this medication, tell your doctor if you have

kidney disease;
liver disease;
a stomach ulcer;

asthma;

urinary retention;

an enlarged prostate;

hypothyroidism;

seizures or epilepsy;

gallbladder disease;

a head injury;

Addison's disease; or

a history of drug or alcohol addiction.

You may not be able to take acetaminophen/caffeine/dihydrocodeine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

This drug combination is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. It is not known whether this drug combination passes into breast milk. Do not take acetaminophen/caffeine/dihydrocodeine without first talking to your doctor if you are breast-feeding a baby. If you are older than 60 years of age, you may be more likely to experience side effects from this therapy. Your doctor may prescribe a lower dose of the medication.

How should I take acetaminophen/caffeine/dihydrocodeine?
Take acetaminophen/caffeine/dihydrocodeine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse or doctor to explain them to you.

Take each dose with a full glass of water. Acetaminophen/caffeine/dihydrocodeine can be taken with food or milk if it causes stomach upset. Do not take more of this medication than is prescribed. If the pain is not being adequately treated, talk to your doctor.
Do not stop taking acetaminophen/caffeine/dihydrocodeine suddenly if you have been taking it continuously for more than 5 to 7 days. Stopping suddenly could cause withdrawal symptoms and make you feel uncomfortable. Your doctor may want to gradually reduce the dose.

Constipation may be a side effect of treatment with acetaminophen/caffeine/dihydrocodeine. Increasing the amount of fiber and water (six to eight full glasses) in the diet may reduce constipation.
Do not share this medication with anyone else.

Store acetaminophen/caffeine/dihydrocodeine at room temperature away from moisture and heat.

What happens if I miss a dose?
Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking the next dose.


What happens if I overdose?
Seek emergency medical attention if an overdose is suspected.
Symptoms of an acetaminophen/caffeine/dihydrocodeine overdose include slow breathing, seizures, dizziness, weakness, loss of consciousness, coma, confusion, tiredness, cold and clammy skin, small pupils, nausea, vomiting, ringing in the ears, and sweating.


What should I avoid while taking acetaminophen/caffeine/dihydrocodeine?
Avoid alcohol while taking acetaminophen/caffeine/dihydrocodeine. Alcohol can greatly increase drowsiness and dizziness caused by the medication which could be dangerous. Also, alcohol increases the risk of stomach bleeding when taking acetaminophen. Use caution when driving, operating machinery, or performing other hazardous activities. Dihydrocodeine may cause drowsiness. If you experience drowsiness, avoid these activities.
Do not take other over-the-counter and prescription products that contain acetaminophen. Too much acetaminophen could be dangerous. Talk to your doctor or pharmacist before taking any over-the-counter preparations.

Drowsiness or dizziness caused by acetaminophen/caffeine/dihydrocodeine may be increased by other drugs such as antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Together, these medicines may cause dangerous sedation, possibly resulting in unconsciousness or death. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.


What are the possible side effects of acetaminophen/caffeine/dihydrocodeine?
If you experience any of the following serious side effects, stop taking acetaminophen/caffeine/dihydrocodeine and seek emergency medical attention or contact your doctor immediately:
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

slow, weak breathing;

seizures;

cold, clammy skin;

severe weakness or dizziness;

unconsciousness; or

black, bloody, or tarry stools or blood in the urine or vomit.

Other, less serious side effects may be more likely to occur. Continue to take acetaminophen/caffeine/dihydrocodeine and talk to your doctor if you experience

constipation;

dry mouth, nausea, vomiting, or decreased appetite;

dizziness, tiredness, or lightheadedness;

muscle twitches;

sweating;

itching or rash;

decreased urination;

decreased sex drive; or

ringing in your ears.

Acetaminophen/caffeine/dihydrocodeine is habit forming. Do not stop taking it suddenly.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect acetaminophen/caffeine/dihydrocodeine?
Do not take acetaminophen/caffeine/dihydrocodeine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.

Drowsiness or dizziness caused by acetaminophen/caffeine/dihydrocodeine may be increased by other drugs such as antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Together, these medicines may cause dangerous sedation, possibly resulting in unconsciousness or death. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

Do not take other over-the-counter and prescription products that contain acetaminophen. Too much acetaminophen could be dangerous. Talk to your doctor or pharmacist before taking any over-the-counter preparations.

Drugs other than those listed here may also interact with acetaminophen/caffeine/dihydrocodeine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including vitamins, minerals, and herbal products.


Where can I get more information?
Your pharmacist has additional information about acetaminophen/caffeine/dihydrocodeine written for health professionals that you may read.
What does my medication look like?
Acetaminophen/caffeine/dihydrocodeine is available with a prescription under the brand name Panlor DC and Panlor SS. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.01. Revision Date: 1/27/05 3:51:56 PM.

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Members' Comments
Posted by pettislinda on March 29, 2007

I have used this medication for some time now and found that it is the best migrane medication on the market. Usually I have spots in my eyes, so I know that if I don't take something right away that it won't be long before excruciating pain sets in. However, this medication works even after the pain sets in, if you aren't able to take something right away. It usually only takes one pill to get rid of the migrane. Before this I uses to take between 4 to 6 midrin to relieve a bad migrane.
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How similar is this to hydrocodone? Is the effect the same? How much codeine would I need to take to equal the effect of say 10mg of hydrocodone?

Are they also known as df's. Only i use to have an accuantance who used herioin and he had tablets who used to help him feel better when he couldn't get any smack or wanted to cut down or stop his useage. They definately weren't subutex and they wre white.

The other 90% of the pill depends on what manufacturer makes it. The thing about most opiate medications, with the exception of things containing lots of APAP is that the bulk of the pill is not the medication. This is true across the board from US FDA approved forms of meds to shady third world manufacturers...go look at RX list. OC 80mg have everything from nitrocellulose and methylparaben to sodium hydroxide in them as "pill fillers" or "gak." If you have 80mg of a pure compound such as OC, or DHC, it is about the size of a paper match head...apparently people loose pills that small or something because no one wants to make them lol!

Junkies will sometimes use (put in a spoon) whatever they can get their hands on. OCS etc. Stupid to do with all the fillers since it can clog the arteries..

Junkies will do just about anything to get their fix, that shouldn't be a surprise to anyone.

As for a comparison between hydrocodone and DHC, you would have to take so much DHC that constipation would make taking enough DHC to be equal to 10mg of hydrocodone not very well worth it.

To be more specific, DHC is 5 to 10 times weaker than hydrocodone. Depending a little on the amount of APAP if any in the Hydrocodone.

The 'Diffs' refers to the original brand-name of the product: DF118. The manufacturer was Duncan, Flockhart & Co.

DHC is now the drug of choice by the World Health Organization to wean off Methadone addicts from their vices. Now that says a lot about DHC.

WHat does DHC break down into? What are the metabolites?

Dihydrocodeine is metabolized into several metabolites (in order of prevalence after 2hrs): Dihydromorphine, hydromorphone (Demerol), hydrocodone/oxycodone. NOTE: the latter two are produced in such small amounts that we can ignore them. The chief metabolite, Dihydromorphine, is produced (actually de-methylated from the dihydrocodeine...aka, taking out the methyl group) via the P450 enzyme in the liver. Codeine/dihydrocodeine itself is actually not active in the body until the methyl group is removed: Codeine/dihydrocodeine MINUS methyl group= Morphine/dihydromorphine. Hope this helps!

DHC is metabolized into dihydromorphine with and dihydromorphine-6-glucuronide (one hundred times more potent), these metabolites are produced in such small amount that they do not have clinically important effects.

I don't comprehend the above scientific lingo at all submited by Tr1n3ty???? No such relation between hydromorphone (really Dilaudid) and Demerol or Oxy/Hydro. Where did you come up with that nonsense Tr1n3ty???

It is metabolized into morphine just like codeine is.
I don't know where all of that gibberish about Demerol, oxycodone, hydrocodone came from.

Really? Most websites state it's broken into Dihydromorphine. Even the LabCorp drug testing site states that it does not break into Morphine and has to be tested for seperately, as does every other site I've come across. However, it does not show up in a drug test, as would morphine, herion, and codeine. I found that out first hand after the research.

Remember, MartinD is the always correct.

PrivateRealm, your research concurs with mine. DHC is metabolized into dihydromorphine and will not show on any standardized drug tests and must be tested for specifically.

You guys are absolutely right. Specifically into dihydromorphine. The difference is related to the semi-synthetic nature of DHC versus opiate codeine.
Nobody is always correct!

Oh well, I got the Brand names wrong, and with all of them out there that is acceptable, however the basic fact and point of my post is this: Dihydrocodeine--->Dihydromorphine. Sorry for the technical aspect of it, but it was overall correct. Hope this helps.

The amount of Dihydromorphine is negligible, so not an issue as far as potency and if it isn't tested for. Also, in this area, the old grapefruit topic comes up:

Codeine and Tramadol. It reduces the amount of codeine converted by CYP3A4 into norcodeine thus increasing the amount metabolised into morphine.

I swear, maybe i like the stuff but GF juice always seems to help my med potency.

alot of people like the "opiate itch"