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#91635 - 01/14/07 06:10 AM Re: Contugesic - Dihydrocodeine (DHC) ***
pillar Offline
GRAND Pooh-Bah

Registered: 11/07/06
Posts: 1902
Loc: The Doors of Perception
You're right. For some reason I was thinking 1/4 cup was 4oz not 2oz and even then I was still off. At least I got the tsp to Tbsp thing right . It's still way too expensive, using the correct math. Nice catch.
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"God deliver us from such criminal imbecility."

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#683051 - 04/12/08 09:21 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: pillar]
fiora Offline
Stranger

Registered: 08/18/07
Posts: 14
Is rxvouge the only source for dhc?

I've seen several scammers claiming to sell it and even sch II's (via Hushmail accounts) but people got ripped off.

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#683090 - 04/13/08 02:43 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: fiora]
funbag Offline
Banned. Crook and shill that managed to fool us all for too long...
Pooh-Bah

Registered: 05/30/06
Posts: 927
medsdeluxe.com

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#696685 - 05/11/08 06:41 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: funbag]
stits Offline
GRAND Pooh-Bah

Registered: 10/15/05
Posts: 2362
Loc: Stitsville, Virginia
Nope. That is NOT legit as of this posting. Funbag did you mistype it? Did you intentionally do so to protect it...

I'm all over the place trying to give you benefit of the doubt but -

The reality is, fake sources is helpful to no one and a waste of time.

Thanks,
Stits
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#696880 - 05/11/08 06:18 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: stits]
RubixCubeTO Offline
Pooh-Bah

Registered: 08/14/07
Posts: 1194
Loc: going down?
hey stitsy - relax - funbag posted that back on 4/13 - when you go to the site ya get this lil message:

Notice: This domain name expired on 04/27/08 and is pending renewal or deletion

I really don't think it was funbag's intention to "dupe" anybody.
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Peace,
~Rubix~


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#696906 - 05/11/08 07:32 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: RubixCubeTO]
funbag Offline
Banned. Crook and shill that managed to fool us all for too long...
Pooh-Bah

Registered: 05/30/06
Posts: 927
Rubix,

Thank you. When I made my post their website was silll up and yes I see the subscription to the website expired 4-27 so until they renew it their site is down...

Why are most of you people so angry all of the time?

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#696924 - 05/11/08 07:56 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: funbag]
RubixCubeTO Offline
Pooh-Bah

Registered: 08/14/07
Posts: 1194
Loc: going down?
 Originally Posted By: funbag
Rubix,

Thank you. When I made my post their website was silll up and yes I see the subscription to the website expired 4-27 so until they renew it their site is down...

Why are most of you people so angry all of the time?



being in pain and not able to get relief tends to bring out the worst in people, I think.
_________________________
Peace,
~Rubix~


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#697037 - 05/12/08 07:21 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: RubixCubeTO]
JokerOwling Offline
GRAND Pooh-Bah

Registered: 07/14/07
Posts: 1971
Loc: here at the moment
Can anyone explain to me what is meant by this statement from the DHC CONTINUS data sheet:
"Unlike morphine, dihydrocodeine is not a full agonist. Increasing the human dose beyond 240mg/day does not produce useful additional analgesic effect."

I have been unable to find any info that expands or clarifies this point.I know what a full agonist is,but what are they refering to here specifically?
I would also somewhat disagree that 240mg/day is a ceiling for analgesia.Anyone else with severe pain find this to be true/false?

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#697048 - 05/12/08 07:43 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: JokerOwling]
nephro Online   crying
GRAND Pooh-Bah

Registered: 09/04/06
Posts: 10267
Loc: NOT 40!
There is certainly a ceiling with codeine, as the body cannot metabolise more than a certain amount at once. Maybe this is true for DHC? I wouldn't have thought this didn't qualify it as a full agonist, though.

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#697103 - 05/12/08 10:00 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: nephro]
JokerOwling Offline
GRAND Pooh-Bah

Registered: 07/14/07
Posts: 1971
Loc: here at the moment
 Originally Posted By: nephro
There is certainly a ceiling with codeine, as the body cannot metabolise more than a certain amount at once. Maybe this is true for DHC? I wouldn't have thought this didn't qualify it as a full agonist, though.

Yeah,the codeine ceiling I agree with,DHC seems to be quite different in this respect.I use it occasionally,but I know others that use quite high amounts,and they(and I) continue to achieve analgesia.The word "useful" seems vague.
I am more interested in what they mean by "full agonist".Every source I have seen,whether it be written text,or on the internet,only ever refer to it as a full agonist.
If anyone has a reference,I would greatly appreciate it.

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#697147 - 05/12/08 11:49 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: JokerOwling]
JokerOwling Offline
GRAND Pooh-Bah

Registered: 07/14/07
Posts: 1971
Loc: here at the moment
I should have written above: I am more interested in what they mean by "not a full agonist".
I ran out of time to edit it.

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#697247 - 05/12/08 02:27 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: JokerOwling]
nephro Online   crying
GRAND Pooh-Bah

Registered: 09/04/06
Posts: 10267
Loc: NOT 40!
Perhaps they are saying that after a certain dosage (240mg they state, which could be an average value of a small study), the drug no longer is able to have additive effects, at least on a linear scale. It does seem a strange choice of words, but at least they didn't call it a 'partial antagonist' or something, which would have really complicated things.

You're right in that all other sources claim it to be a full agonist, but they will be referring to normal therapeutic doses, which at the moment are considered to be no more than 240mg/day. They won't describe what happens beyond this, because if more than this is required, the doctor will prescribe a stronger opioid.

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#697619 - 05/13/08 08:29 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: nephro]
JokerOwling Offline
GRAND Pooh-Bah

Registered: 07/14/07
Posts: 1971
Loc: here at the moment
It would be great if the writers of these data sheets expanded the information a little.Even placing what you wrote above would be more helpful.The way its(the data sheet)worded sort of implied that it may be a partial antagonist,thats why I asked for any reference.I was thinking along the same lines as what you said.
I think DHC is an under utilised medication,especially in Aus.

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#697622 - 05/13/08 08:42 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: JokerOwling]
nephro Online   crying
GRAND Pooh-Bah

Registered: 09/04/06
Posts: 10267
Loc: NOT 40!
I totally agree, and I wonder if sending an e-mail to the producers of the sheet would make a difference? Dihydrocodeine orally is probably one rung below morphine on the analgesic ladder, and is used quite liberally in UK hospitals as part of the modern polypharmacy version of pain management, as pain relief in its own right, and as a standard take-home medicine following hospitalisation.

Perhaps some authorities don't see it as a substantial enough improvement over codeine, especially since it shares the same side-effects.

It is likely to be used more in the UK now that patients are not able to continue their co-proxamol, and possibly as more problems with Tramadol emerge.

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#698060 - 05/13/08 11:54 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: stits]
funbag Offline
Banned. Crook and shill that managed to fool us all for too long...
Pooh-Bah

Registered: 05/30/06
Posts: 927
Yeah,
Stits what's the deal of your rude post to me about medsdeluxe.com. When I posted that on 4-13 their website is alive and well. If you look at it now it says their domain name expired as of 4-27. Perhaps if some of us took some time to read that'd be great. And once again I'd like to point out that alot of the people on this board have no manners. I keep saying it but it falls on deaf ears but we are here to help each other out. (except for those promoting the .info sites)

Stits I think an apology is in order here and you really need to relax instead of going off on me. When I am wrong (and I am sometimes we're all human) at least I have the balls to admit it.

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#698283 - 05/14/08 11:26 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: funbag]
JokerOwling Offline
GRAND Pooh-Bah

Registered: 07/14/07
Posts: 1971
Loc: here at the moment
I think it was said without anger,maybe I'm wrong(stits,maybe you can clear things up for funbag).
Stits has a unique way of posting that often confuses people.
No offence stits,I enjoy your style,sometimes its a challenge to interpret,but I love a good challenge.

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#703820 - 05/24/08 12:14 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: hibbs]
Patsmag Offline
Member

Registered: 02/02/03
Posts: 94
Loc: New England
I've until very recently, been getting DHC 30's from Hong Kong. But As of this week they'll no longer accept Visa or any other Debit type of card. It's risk your credit, or pay 40-60 bucks for wire transfer. This is what I was told by the pharmacist. I'd been doing business with them with a Visa debit card for years, with never a problem. And yes, I prefer DHC over most all other narcs. It's very easy to come off of, a slow taper, or switch to T & C#3 and you're done. None of the nasty sides like on oxycodone or even hydrocodone. PM me if you want to know the name of this pharmacy. It's not their fault they can't take Debit cards. They're just taking orders, just like the rest of the Chinese population unfortunately.
dr patrick.


Edited by Patsmag (05/24/08 12:16 PM)
Edit Reason: spelling
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#704635 - 05/26/08 07:44 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: Patsmag]
JokerOwling Offline
GRAND Pooh-Bah

Registered: 07/14/07
Posts: 1971
Loc: here at the moment
Patsmag,how are you paying now,by bank transfer or WU or some other way?
Are you able to post the name of the pharmacy,as I think its against the Rules to PM for the source.

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#718796 - 06/24/08 12:40 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: JokerOwling]
trulyevil Offline
Stranger

Registered: 02/22/04
Posts: 9
Loc: The Republic of Texas
Just curious whether anyone knows what the heck happened to the pharmatico.com site. They were a decent source for DHCs until they sort of dried up in the early 2000s (I'm talking about the "Contugesic"/"Didor Continus" variety, that come in 60, 90 and 120 mg caplets, not those little round 30mg DF jobbies). Then the site disappeared for a while. It's back now, but has no list of meds at all - just lists of pretty much useless links. Now, pharmagroup.com has references to DHC in several places on their site, but it doesn't appear on their list of pain meds anywhere (I've got an inquiry in to them about that now). Good news is, I do have an email source that I trust, but the price is high ($8 apiece for the 90mg pills) - so I'm on the lookout for a more cost-effective source.
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#777776 - 10/03/08 04:16 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: Melody]
Hard_man Offline
Stranger

Registered: 08/28/08
Posts: 3
Pharmatico was actually closed down by FDA, thats what I heard. dihydrocodeine is no longer being made, so anyone offering this has either a stock thats 2-3years old so product about to go bad or is a scammer.


Edited by Hard_man (10/03/08 04:17 AM)

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#777968 - 10/03/08 10:16 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: hibbs]
Oxy80 Offline
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Registered: 03/30/08
Posts: 2284
Loc: Follow the yellow brick road
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#791725 - 10/25/08 08:04 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: Oxy80]
bladerunner Offline
Threadhead

Registered: 07/27/08
Posts: 870
Loc: Western USA
Above link seems to be bad.

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#791832 - 10/25/08 09:54 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: Hard_man]
JLSUK Offline
Banned. Solicitin. Using our PM system to solicit
Newbie

Registered: 05/30/08
Posts: 31
 Originally Posted By: Hard_man
Pharmatico was actually closed down by FDA, thats what I heard. dihydrocodeine is no longer being made, so anyone offering this has either a stock thats 2-3years old so product about to go bad or is a scammer.




Dihydrocodeine still in UK
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#791834 - 10/25/08 09:56 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: bikerhoney]
Ludes_Vet Offline
Board Addict

Registered: 11/29/04
Posts: 332
Loc: Southeastern U.S.
Pure Dihydrocodeine is offered in the following countries:
1. Austria "Codidol" & "Paracodin"
2. Australia "Paracodin" & Rikodeine"
3. Belgium "Codicontin" & "Paracodine"
4. France "Dicodin"
5. Germany "DHC" & "Paracodin" & "Paracodin N" "Remedacen"
5. Germany (continued) "Tiamon Mono"
6. Hong Kong "DF 118"
7. Ireland "DF 118" & DHC Continus" & "Hydol" & "Paracodin"
8. Israel "DHC Continus"
9. Italy "Paracodina"
10. New Zealand "DHC Continus"
11. Portugal "Didor" & "Paracodina"
12. S. Africa "DF 118" & "Paracodin"
13. Spain "Contugesic" & "Paracodina" & "Tosidin"
14. Switzerland "Codicontin" & "Hydrocodeinon" & "Paracodin"
15. UK "DF 118" & "DHC Continus"
Source: The Martindale 33rd Edition (The Complete drug Reference) by Pharmaceutical Press Publications Division of the Royal Pharmaceutical Society of Great Britain 2002*
* There is a newer "Martindale" book out 2007 edition, but I do not have immediate ready access to it. The Martindale
also publishes the manufacturer of each "brand name" in each respective country, but to save typing time I skipped that info that is in each of the Martindale books.

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#791840 - 10/25/08 10:00 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: Ludes_Vet]
Rock77 Offline
Member

Registered: 10/22/08
Posts: 110
I've read that SSRI's block the effect of codeine. Is this also true for dihydrocodeine?
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#791843 - 10/25/08 10:03 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: Ludes_Vet]
JokerOwling Offline
GRAND Pooh-Bah

Registered: 07/14/07
Posts: 1971
Loc: here at the moment
 Originally Posted By: Ludes_Vet
Pure Dihydrocodeine is offered in the following countries:

2. Australia "Paracodin" & Rikodeine"

Paracodin is no longer available in Australia.

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#844865 - 02/15/09 02:38 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: OldandWorn]
spongebob123 Offline
Journeyman

Registered: 02/07/09
Posts: 65
Loc: alabama
HI.HAS ANYONE BEEN HAVING SEVERE NIGHTMARES AFTER TAKING DHC?I JUST STARTED TAKING DHC ABOUT A MONTH AGO AND NEVER HAD NIGHTMARES LIKE THIS BEFORE.I THOUGHT MAYBE IT WAS ME SO I WENT TO MY FAMILY DR. AND GOT TYLENOL3 AND THE NIGHTMARES WENT AWAY.I TRIED DHC AGAIN AND SAME THING,NIGHTMARES CAME BACK.AM I THE ONLY ONE?
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#855447 - 03/07/09 07:39 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: therhino]
RINGSAK Offline
Stranger

Registered: 08/24/08
Posts: 1
Loc: Boulder, Colorado. USA
HELLO, Although people like to think they know everything. Still, very little is known about requirements for opioids/benzos/and other narcotics-pain killers.
There is relatively new research that UNDENIABLEY PROVES:(scientific, not some "know-it-all" claiming people dont need pain-killers)"Some people require opioid medication even if they do not suffer from chronic retrectable pain. Genetically, some of us are predisposed w/lower levels of dopamine and/or the in-ability to produce this chemical."
I hope this helps you out, the next time some family member or co-worker gives you [censored] for taking pain meds.
Scott... Stewart Racing Inc. Boulder,CO

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#855579 - 03/08/09 06:51 AM Re: Contugesic - Dihydrocodeine (DHC) [Re: Laurelolo23]
bronko Offline
Banned. Soliciting to trade meds
Member

Registered: 01/11/04
Posts: 136
Loc: So Cal
I think the more knowledgable would be a pharmacist.Dr's only spend a short time in med school learning pharmacology, a short course, 2nd yr.

Went to see my doctor for a physical,he asked to turn around and bend over.
I said "Doc, what are you doing?" , "examining your prostate"
he said. I replied "with both hands on my shoulders?"


Edited by bronko (03/08/09 06:58 AM)

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#859122 - 03/13/09 08:41 PM Re: Contugesic - Dihydrocodeine (DHC) [Re: Patsmag]
opy Offline
Newbie

Registered: 02/24/05
Posts: 32
Hey Patsmag,
could you PM me, the site says I have to have 25 posts in order to PM someone, thank you in advance,
Opy

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