Have you read anything on these forums. Im sorry if this is rude but it just eats me alive when ppl post on the 15th page of a topic like this with such a root and fundimental question. Good lord. read just a tiny bit and research a tiny bit here and you will see.

Just tossing up an address and wanting someone to send info... LAZY!

Im sure you will get plenty of email to that address now...

I think alprazolam works wonders for anxiety. I stopped taking it altogether after taking approximately 3-4 2mg pills a day and passed out. A weak later I was dehydrated on a hot day and hit my head on a tile floor and went into seizures... not fun. Be careful with this drug!

Saw this on Wiki,

Some anti-drug sources[who?] provide disinformation by stating that alprazolam is more potent when taken with cola--the acidic nature of colas actually decreases its absorption--acidity decreases the absorption of most orally taken pharmaceuticals.

So avoid that cola, or maybe even Vitamin C? when taking alprazolam. (providing this is true )

That's interesting and, if true, bad for me since I drink sodas all day long!! Man, I guess I'll have to start drinking water now....

I wouldn't have thought such a weak acid such as carbonic acid would have any measurable effect on the strong HCl in the stomach.

I have never heard of cola lowering absorption but i did hear that grapefruit increases it, can anyone clarify this?

Grapefruit Juice/pulp inhibits a liver enzyme responsible for the breaking down of alprazolam, as well as a host of other medicines. I believe oral bioavailability of alprazolam is around 92% though, so I'm not sure that drinking grapefruit juice would significantly raise blood serum levels of the drug. I could be wrong, but I think that's about right. Please someone correct me if I'm wrong.

Personally, I can't stand the taste of grapefruit juice in either pure or concentrate form...so I don't have any personal experience with the interaction between the two. I'd suggest looking around a bit on the internet for info like this, there are a lot of studies and charts on enzyme substrates/inducers/inhibitors out there. Have a good one.

Kai

I just don't see how this can be right. Isn't Wiki the site where people can just randomly edit the content?? If so, this may be the case here.

I'm with you about the taste of grapefruit juice. Can't stand it. But I have received a prescription for Diazepam that had warning labels about not taking with any grapefruit product, so there may be something to this if it applies to alprazolam also.

About the cola reference I quoted from Wiki, I have no idea if this is true or not. Wiki Can contain mis-information as someone pointed out. That "[who?]" was part of the article.

A serious dig at real medical sources could probably clear this up. Sounds like a project for an intrepid medical student or someone who loves to do medical research.

Well, the text on Wikipedia stating, "As with all drugs, taking it on an empty stomach ensures the most powerful effect" annoyed me too. Not only is it false, but potentially dangerous as some drugs should be taken with food. So I've deleted it.

LoL, I thought that was true.

It's true for MANY drugs but by no means ALL. One can tell whether a Wiki article is of any value by the words the writers use. Such a sweeping statement does not give much credibility to the work.

Pancreatin is another drug that works best with food.

I was also just reading about extended release Morphine Sulphate and the literature stated it could be taken without regard to food, it did not matter either way. Just another example of ALL not being accurate.

Indeed, ER morphine capsules may be opened and the contents sprinkled onto soft food. The point with this drug is to keep a steady level in your body, not to obtain a quick onset.

So is the time release technology contained in the ingredients of the capsule instead the actual capsule itself? I read that you could sprinkle the contents on applesauce or something of the like but, was a bit confused on how the time release would still be effective if you did this.

Also, have you ever taken this drug? If so, how does it compare to regular oral Morphine?

I think it's assumed that the beads or pellets inside the capsule won't be significantly crushed when taken with soft food, because it doesn't need chewing that much.

I've not taken slow-release morphine, as it's not really suitable for acute pain.

Ok, here's a good question. Read somewhere recently (on this board) that ksalol is one of the best generics. Then i look for it, and maybe an IOP has it, so I write them and they say:

We have 2 types from LabormedPharma and Gedeon Richter.
The both are high quality - stronger than Ksalol.

Never heard of either. Has anyone? What do you think of this recommendation?

I was checking this our as it is heating up out here and I "heard" that improper temperature storage can ruin alprazolam. Called the pharmacy and he looked up the recommended storage temps and they were between 60 and 86 degrees F. Then I checked an online Pharmacia/Upjohn insert and it said "Store at controlled room temperature 20° to 25°C (68° to 77°F"). Why the difference I wonder? Maybe generics are more sturdy than brands? I asked the pharmacist if it were better to store at a lower temperature than recommended and he said definitely yes. So refrigeration (not freezing) seems to be the best thing for the summer heat at least for alprazolam. If anyone has different information about this Please post it!

water and condensation can break down many medications...

i would not keep any pk's or benzos in the fridge for that reason alone.

you would get condensation inside the bottle, which would lead to a lot of moisture which is not good.

store in a cool, dark, DRY place... preferably not in the medicine cabinet in the bathroom either, as i have read in many places that the condensation from the shower can harm the meds as well...

i keep mine in my sock drawer! (no kids or they would be in a safe in the closet)

Unless they were already a liquid formulation and stated to refrigerate.

Well, I basically have 2 options, refrigerator or somewhere cool in the house. Problem is that we let the inside temp run up into the 90's during the day on one of those fancy thermostats. The first summer we used this it saved us over $100 a month, and that was 10 years or more ago, so that is not going to stop what with the price of energy today!

I will try the safe though, leave the door open during the night and then close it up during the day, with benzo's inside. Should stay cooler during the day. I have been testing places in the house, using one of those inside/outside thermometers. I will test the safe tomorrow. Someone else who lives here thinks I am nutty and anal retentive about this, But I will find the right spot and Ha! to that Someone else.

ever think of throwing one of those plastic cooler freezer ice thinngymabobs? maybe wrap in a few paper towels and it would keep the safe cool all day while the paper towel sucked up all the moisture...

just a thought if your house is at 90 all day...

Worst place for meds is in a bathroom or a damp basement. In regular air conditioning, sealed in plastic is best. The "sock drawer" is a good option. Unless you live in the desert (yes!!), meds break down from the humidity..

I do live in the desert, most of the time, so what is the best solution, in the refrigerator inside a plastic bag? Perhaps one of those foodsaver bags where you suck all the air out? Some of the pills are in a plastic bottle (vitamin bottle), some in blisters.

Like I said earlier, we let the house temperature go up during the unoccupied daytime into the 90's. It starts cooling down before we get here and is nice when we actually get home. That little thermostat has saved us literally $1000's since we got it.

Depends what the humidity is in the fridge.

Why would you want to make a carcinogenic dye used to detect blood stronger?

Title put back.

Congratulations on your most intelligent post yet, and well done for not changing the title to your own personal question. Tell your junior school teacher you deserve a sticker in your exercise book.

Go somewhere else please... no one needs your childish antics here. I tried to Notify, but it seems plenty of others have already notified the moderators about your ridiculous posts. I just don't get why people like you even bother joining boards like this. I haven't heard someone say something like that since I was around a bunch of teenage/high school kids. We are all here to help and enjoy each other's conversations, but it's obvious you are not.

This troll will probably be banned very, very soon.....

There's no need to make brainless posts like that! We are all here to help each other.

When you see a post you don't like you should report it. If it's already been reported you should just move on. Responding to posts like this is improper to say the least.

I try to live by this rule, but am in no way trying to moderate the board but rather offer up my opinion.