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#133170 - 12/23/04 04:06 PM Lomotil -an antidiarrheal med -that contains a Narocotic
DigitFreedom Offline
Enthusiast

Registered: 12/03/04
Posts: 222
Loc: U.S.A.
Would someone please be so kind as to share some basic info abut the antidiarrheal drug Lomotil? I was prescribed this yesterday, and I just read that it contains Diphenoxylate HCl which (by it's self) is a Schedule II narcotic related to Demerol (meperidine), but when combined with tatropine sulfate it is a Scedule V narcotic. Wow, I never thought something as simple as an an antidiarrheal med would be anything of this nature.

Does anyone actually abuse this stuff? More importantly, I must ask if anyone has suffered any serious reactions to the atropine combined in it to lessen abuse of the product. From what I have read; atropine can cause very very bad side effects, and Im rather concerened it's something I dont really need to be taken at all. In fact, Im almost ready to get something over the counter instead.

Thanks.
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#133171 - 12/23/04 06:21 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
ikestormu11 Offline
Old Hand

Registered: 06/02/04
Posts: 376
Loc: right coast
I've used lomotil in the past for its intended use. The ones I was prescribed were the smallest pills I've ever seen. One of them worked well as an AD. I THINK that one pill contains a trace amount of Diphenoxylate HCI. You'd probably have to take a hundred lomotil's to have enough Diphenoxylate HCI in you to make a difference in how you felt. One things for sure if you take a bunch of lomotils you won't be using the can for days. I kind of believe in the saying "never say never" but I'd find it hard to believe people were abusing lomotil. Anyway's if you need a highly effective AD lomotil is a life saver.
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#133172 - 12/23/04 08:02 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
jack_in_ca Offline
Member

Registered: 06/01/03
Posts: 107
Loc: California
Quote:

Would someone please be so kind as to share some basic info abut the antidiarrheal drug Lomotil? I was prescribed this yesterday, and I just read that it contains Diphenoxylate HCl which (by it's self) is a Schedule II narcotic related to Demerol (meperidine), but when combined with tatropine sulfate it is a Scedule V narcotic. Wow, I never thought something as simple as an an antidiarrheal med would be anything of this nature.

Does anyone actually abuse this stuff? More importantly, I must ask if anyone has suffered any serious reactions to the atropine combined in it to lessen abuse of the product. From what I have read; atropine can cause very very bad side effects, and Im rather concerened it's something I dont really need to be taken at all. In fact, Im almost ready to get something over the counter instead.

Thanks.




The sub-therapeutic dose of atropine is added to Lomotil to discourage abuse, because it will cause some nasty side effects *only* if you try to take enough diphenoxylate to get narcotic effects. It's not an issue if you use the prescribed dosage to control diarrhea.

Peace,
Jack


Edited by jack_in_ca (12/23/04 08:03 PM)
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#133173 - 12/23/04 09:26 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
Farmer Offline
Enthusiast

Registered: 12/23/01
Posts: 58
Actually, I was prescribed this once and since I "really needed" it urgently, for the prescribed reason I took four at once and went to bed. I did not realize that it was a narcotic or that Atropine could be a nasty thing.

Anyway, after taking four and going to bed, I woke up feeling great. Relaxed and quite comfortable. Then I read up on the med and found out why I felt so good. I've never taken more than 4 at once, and would not suggest anyone else try it. I'm not sure exactly what atropine does, but it does do something because my pupils got huge, but that is the only thing I saw happen. Again though I wasn't trying to get high, just head off a major stomache issue.

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#133174 - 12/23/04 11:21 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
pecans Offline
Journeyman

Registered: 12/18/04
Posts: 61
yeah, that's kind of a little over the top for that. My gastrointrologist t, I have IBS, told me to just take plain ol immodiumad...He said you can't OD on it and you can take alot at a time. I take 4 every morning. that works for me. And it is derived from the codeine products anyway........

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#133175 - 12/24/04 11:41 AM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
Opie_Yates Offline
Veteran

Registered: 08/11/03
Posts: 574
Loc: Out the Doghouse's Back Door
I'll never forget the day I walked into my local Walgreens. I wasn't sure if Lomotil was one of those "under the counter" over the counter meds, so I asked the pharmacist, who knows me from my hydro prescriptions. She shot me a glare and she said "Great, now your looking to abuse diarreha medicine. Why don't you just go get some Immodium off the shelf." Wide-eyed in shock, I shot back, "uh...no thanks, I'm done with Walgreens and I'm going to tell your corporate offices why." Walgreens IS truly evil.
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#133176 - 12/24/04 03:33 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
DigitFreedom Offline
Enthusiast

Registered: 12/03/04
Posts: 222
Loc: U.S.A.
Quote:

I'll never forget the day I walked into my local Walgreens. I wasn't sure if Lomotil was one of those "under the counter" over the counter meds, so I asked the pharmacist, who knows me from my hydro prescriptions. She shot me a glare and she said "Great, now your looking to abuse diarreha medicine. Why don't you just go get some Immodium off the shelf." Wide-eyed in shock, I shot back, "uh...no thanks, I'm done with Walgreens and I'm going to tell your corporate offices why." Walgreens IS truly evil.






Thats funny, yet very uncalled for. I would not boycott Walgreens entire business, but I would advoid that pharmacist ('might even tell others).

UPDATE:

I received an email from an old friend of mine today that had a story of someone that acidentially took too many of these pills. He claims his friend took somewhere between 6-10 Lomotil pills one night due to the fact he was drinking and wasnt making smart decisions. The report is that they made him feel very bad... He had nightmares all night long, nerves were shot to the point that the room was spining, and he got very dehydrayted to the point he suffered an all day long intense sinus headache.

So, on the surface of it... I cant understand how anyone could abuse this product to get high on it. It seems to be one of those drugs that should not be sceduled as it currently is.

Peace.
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#133177 - 01/27/05 12:02 AM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
Beetlenut Offline
Threadhead

Registered: 09/09/02
Posts: 350
Loc: Colorado
I have been on Lomotil for many years for severe IBS. And, yes, the active ingredient is a derivative of demerol. I was told by a drug rep that the atropine is added to discourage abuse.

I am on a high dose (8/day-that is the maximum dosage). I can indeed tell you that YES lomotil is abused and I have to be very careful with it. It IS a scheduled drug.

I can tell you that if you take a very large dose, the atropine will have the following effects:

1. Very dry mouth;
2. A bright red face;
3. Some report a headache;
4. Dryness "all over";
5. Urinary retention;
6. Pinpoint pupils; and
7. Most dangerously, it increases your heart rate dangerously high. I am talking about 140 HR; you will also develop very high blood pressure (i.e., 190/140). These vitals DO NOT return to normal for many days despite I.V. fluids.

I once knew someone that took 120 - she wound up in the ER due to the HR & blood pressure issue, but was hospitalized due to a bowel impaction. She was put on the cardiac floor because her heartrate was so extremely high. The impaction DID go away after 2-3 days (after the surgeon came in to consult).

Careful with this med - it's an easy one to abuse but not worth it.
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#133178 - 01/27/05 06:49 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
tone Offline
Threadhead

Registered: 06/29/03
Posts: 847
thats a shame, as some people may be extra sensitive even to low doses of anticholinergics

i dont understand, whats the motive for doing this (preventing higher doses being taken) The must be a motive stronger than losing money because people would consume less. you know the motive cant be geniune altruism and care for the patient so what is it

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#133179 - 01/27/05 07:12 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
JethroMole Offline
Board Addict

Registered: 01/19/05
Posts: 328
I was under the impression that Lomotil is indeed related to demerol but it's obviously not a scheduled drug or it wouldn't be OTC Atropine is a $#!t hit but it's still used for many things. It's an alkaloid that's present in the jimson weed plant, among others and in high doses can be hallucinogenic with an emphasis on unpleasant. Atropine has been used in eye drops too for its pupil dilation effects and for motion sickness too - if I'm not mistaken it's available in a "patch". Best wishes . . .

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#133180 - 01/27/05 07:47 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
BamaChica Offline
Banned. Moderator at europevendor.com. We consider mods as reps for a site. This user not allowed to post as rep.
Pooh-Bah

Registered: 05/28/04
Posts: 896
Loc: Resident Bad Girl....
it isn't OTC..you have to have a script for Lomotil..
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#133181 - 01/27/05 07:54 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
JethroMole Offline
Board Addict

Registered: 01/19/05
Posts: 328
D'oh! You're right - I stand corrected! I was thinking of Imodium. Just looked it up - Lomotil is Schedule V.


Edited by JethroMole (01/27/05 07:57 PM)

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#133182 - 01/27/05 08:34 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
JethroBodine Offline
Board Addict

Registered: 06/20/03
Posts: 239
Loc: Ozark Mountains
In med school they teach a little ditty to help you remember to associate certain symptoms with atropine poisoning: "red as a beat, dry as a bone, mad as a hatter." Atropine is used as a nerve agent antidote. It can also be used in an emergency for asthma attacks, though it is certainly not the best choice. It has some muscle relaxant properties. It's a very odd drug. It both potentiates and counteracts almost any drug you can imagine. Kids looking to get high die at the rate of a few a year from eating or smoking jimson weed and other plants. The seeds are the most potent part of the plant, but the concentration is highly variable. A lethal dose may range from 10 seeds to hundreds. It is the traditional drug witches used to "fly" or have halucinations of flying. It was mixed with animal fat and applied with a broomstick, hence the icon of witches flying on a broom. There a many accounts of people being whacked out for days, not able to tell halucinations from reality; and the halucinations are often terrifying. There are few medical reasons for taking this type of drug, but it is safe within the prescribed limits.
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#133183 - 01/27/05 08:40 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
prettyday Offline
Pooh-Bah

Registered: 02/09/03
Posts: 1384
Loc: Coastal Sage Scrub
Now I know why some people come back from Baja with this...FWIW, I have had really severe colitis that is now diverticulits for years. To be unpleasant, I will not stop going to the...you know. It would strike anytime, anywhere, and I still get it taking pain meds.
Yes, ironically when I get it, the pain meds seem less effective as well (within the same batch; it's my body just chewing itself up, I guess.)
For anybody obsessed with their weight who happens to read this; it's not a coincidence that I have this and I have friends who have diabetes and other problems as a result of our anorexia and bulimia...love yourself...
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#133184 - 01/29/05 03:30 PM Re: Lomotil -an antidiarrheal med -that contains a Narocotic
astrophel2 Offline
Old Hand

Registered: 03/11/03
Posts: 399
Loc: East Coast
I can't believe wallgreens said that!

I used to work in a hospital pharmacy, and remember lomotil being locked up in the "narc room." A long-established co-worker told me that there wasn't much abuse potential in it at all... they were wise to rarely let me in there. My eyes must have glowed too noticeably when I saw myself surrounded by every form of narcotic made--the holy grail of rooms, so to speak.
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