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#129173 - 06/27/05 09:45 PM
Re: Dilaudid (hydromorphone hydrochloride)
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Stranger
Registered: 06/24/05
Posts: 8
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Hi All, Well I am a old time member, 20001, new VIP. Just to add to the thread, I have been on pain management for awhile. I have been on Methadone 20mg, then Kadian 100mg(morphine) 4 times a day and now Palladone 32mg 3 times a day. I have tried Oxycontin 80mg 3 times a day but the side effcts (dark eyes, tired, and very hard to understand). Oxy is a killer and I warn anyone who thinks they can go off after a year is in for a big surprise. Its so addictive I wish it for no one. Palladone is very smooth and easy on the body. No more morning sickness and pain melts away with ease. I suggest this med as IT WORKS. Be careful, its very strong. Next time in I will ask for the BT med at 4mg. Norco bwoks the best for this but never tried the non-ER form so wish me luck. I am the first ever for this med here and must say again. Purdue learned from their mistake with Oxy, its nearly fools proof if you know what I mean. If anyone wants to message me, I would be happy to answere any questions you may have. God Bless
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#129177 - 07/21/05 06:05 PM
Re: Dilaudid (hydromorphone hydrochloride)
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Board Addict
Registered: 01/19/05
Posts: 328
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Yeah, that's interesting about the Palladone recall - what a bummer. Apparently alcohol interferes with the time-released aspect of the drug, causing it to dump a dangerous amount of hydromorphone into the body. (See below) I have to wonder if Purdue Pharma's other big seller - Oxycontin - which is another time released pain med - is affected. If not, why not? Does Purdue use a different time-release mechanism in Palladone than they do Oxycontin? I've often read that when Purdue was asked to re-formulate Oxycontin so that it couldn't be broken down, snorted and/or injected, Purdue responded by saying it was too difficult to mess with the time released aspect of Oxycontin. Anyhoo, here's the unfortunate poop on Palladone: www.fda.gov - "07/13/05 - After acquiring new information that serious and potentially fatal adverse reactions can occur when Palladone (hydromorphone hydrochloride) extended release capsules are taken together with alcohol, the U.S. Food and drug Administration has asked Purdue Pharma L.P., the makers of the drug, to withdraw it from the market. Palladone is a once-a-day pain management drug containing a very potent narcotic. New data gathered from a company-sponsored study testing the potential effects of alcohol use shows that when Palladone is taken with alcohol the extended release mechanism is harmed which can lead to dose-dumping. Dose-dumping is a term that describes the rapid release of the active ingredient from an extended release product into the blood stream. The consequences of dose dumping at the lowest marketed dose (12 mg.) of Palladone could lead to serious, or even fatal, adverse events in some patients and the risk is even greater for the higher strengths of the product. As a result of this potential serious safety risk, the FDA has asked Purdue Pharma, and they have agreed, to suspend all sales and marketing of Palladone in the U.S. pending further discussions with the agency. "All powerful pain management drugs have serious risks if used incorrectly, but the current formulation of Palladone presents an unacceptably high level of patient risk" said Dr. Steven Galson, FDA Acting Director of the Center for drug Evaluation and Research. "Although we have not received reports of serious problems, this product has so far been used in a relatively small number of patients. We are concerned that as more patients take this drug, safety problems will arise since even having one alcoholic drink could have fatal implications. The current labeling for Palladone, approved in September, 2004, already includes the standard opioid warning against the use of alcohol and Palladone. However, the FDA does not believe that the risk of serious, and potentially fatal, adverse events can be effectively managed by label warnings alone and a risk management plan."
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#129179 - 07/21/05 07:50 PM
Re: Dilaudid (hydromorphone hydrochloride)
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Veteran
Registered: 11/08/03
Posts: 492
Loc: southwest US
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Quote:
I am on oxy 80's and percocet. I have had a few spinal surgeries and I am in chronic pain. I went to the er a few times b/c of the severe pain and the doc wanted to put me on a Dilaldid drip, I opted for a few shots of the same medication b/c I didn't want to be in the er all day and night, but the dilaludid didn't help a bit! And the doc gave me a pretty strong dose. Has this happeneds to anyone else?
Yup, me, several times. When my chronic, never ending headaches escalated to a level 10 (thankfully this has not happened in a while) I would go to ER and twice I was admitted. Both times I was on a dilaldid pump, and if it worked at all, it was because it just made me so wasted I didn't give a SHHT. I thought at the time, and still think, that it would have been much better to just put me to sleep for 10 hours or so. I actually did this on my first hospital stay... I had someone smuggle ambien to me, and took two or three. After 8 hours of deep sleep, the headache was gone..... for a while.
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#129187 - 08/10/05 11:34 PM
Re: Dilaudid (hydromorphone hydrochloride)
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Stranger
Registered: 06/24/05
Posts: 8
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Hey dwi1,
Question, your oral surgeon prescribing 80mg Oxy, Dilaudid, and Demerol? Or is the demerol just from the oral surgeon and the big guns from yourr Pain Management Doc? Curious. Looks like the gov would frown on a surgical dentist give Oxy 80's and Dilaudid as both are on the special enforcement. Which means, too many scripts from the doc on these and a visit will be made. I can tell you though, some states have more local help to the feds than others. In CA the locals see everything up to Mary Jane, so the feds like the legal stuff more than the other. Also, I believe CA, if the doc is a registered pain management/Anesthiologist(sp), well they pass on theirs versus the local dentist or Family Doc. CA requires a triplicate and most docs don't even have then. Also, nor do the ER's. Hydro is all anyone will prescribe except the PM
Just curious dwi1, seems like a lot from a surgical dentist.
Take Care, Blaster69
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#129188 - 08/11/05 08:58 AM
Re: Dilaudid (hydromorphone hydrochloride)
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Stranger
Registered: 06/10/05
Posts: 4
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OK. Read my previous posts about my ortho Dr and the confusion I experience with him. ** I just went to see him again on Monday 8/08. I took my wife this time-- as a extra set of ears. We asked about alternative to drugs via surgery or whatever. I am ready to go under the knife or whatever is necessary. Bottom line-- there isn't anything except drugs or the $3,000 Prolotherapy procedure. I asked about the quantity of (4mg) Dilaudid he was prescribing. The Qty is HUGE, and I couldn't figure out the reason (again, see my prev posts). I get a 'script for 448 at a time. When I 1st got in the exam room, one of his nasty staff wanted to know why I never came back in for the last script on July 12. It's been in my folder, but I did not KNOW I had one. I knew there was one for Avinza, but I stopped taking it as it wasn't helping and I don't want to take something-- just to take it. So, there being a new Dil scipt was news to me. I told her-- and the Dr-- that I still have plenty from the last one in June. I hope that convinces them that I am not taking it FOR FUN. I asked him how long it was supposed to last, and he said the 448 was for ONE MONTH. However, I am to take it every 3 hrs. Do the math. I'd have to set my alarm and take it constantly. I think it comes to something like 5 pills every few hrs. That's nuts. I was trying to do the math in my head while he was talking, but I was busy listening to other things. He offered to lower the qty, but as goofy as they are, I don't want to have to deal with a potential shortage later... so i had him keep the amount. As I told him-- better to have it and not need it than the other way around. When he left, my wife and I figured it up, and its no wonder they think I could be abusing it. He gave me yet another one (and they tossed the unfilled July one) which I have not filled, yet. Days later, I STILL have plenty from June. The whole thing is odd... but proof that they're not running a tight operation. Like I said, and repeated to my wife-- "NO WONDER THEY'RE CONCERNED ABOUT IT-- IF THEY THINK I AM TAKING 16+ A DAY!!". They have written down that I NEED that many, but they've done bad math. Until I can find someone to pay for the procedures, I am stuck treating just the pain. If anyone's curious, CVS wants approx $350 for that amount, while it's only $78 at Walmart. Both are the generic. HUGE difference. I had to switch to "cash", as my new insurance won't cover pre-existing. Nice.
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