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#105410 - 02/01/06 03:25 PM
Re: Buprenorphine - Temgesic
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Old Hand
Registered: 01/08/04
Posts: 366
Loc: way up north
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#105418 - 03/27/06 09:43 AM
Re: Buprenorphine - Temgesic
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GRAND Pooh-Bah
Registered: 10/27/03
Posts: 2169
Loc: Bearing Strait Ice/Land Bridge
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Hey guys - to answer a few of your burning questions... First of all - it should be understood that a drug, any drug, has differences in effectiveness based upon how it is administered. Most drugs are most effective and potent when injected IV. IM (muscular) injection is the next highest effectiveness, then comes other ways of administration, such as anal, oral, sublingual. Buprenorphine follows the same pattern, which is why when people swallow the pills, they don't get any effects whatsoever. That's because the body gets to use about 1% of the total dose when swallowed. If taken sublingually, or under the tongue - where the medicine absorbs into the body through a vein located under the tongue, the body is able to use much more of the total dose administered. I don't know the exact percentages so this is rough estimations. Now, if taken by injection, into the muscle, then the body is able to use most of the dose administered. So a 0.3mg injection of Bupe can possibly be equal to 4mg of Bupe taken sublingually, under the tongue. Again - I don't know the exact percentages and whatnot, but I hope you get the general idea. That's why the Suboxone/Subutex doses come in higher mg - because when taken sublingually, more is needed, and also - because these drugs are designed for opiate-dependent and tolerant persons, who usually have quite the tolerance built up. So as far as your doctor and the dose he wants to give you is concerned, this is just my opinion and should really only be treated as just that - an uneducated opinion, but I would say that based on your current intake of opiates, and how you were affected by the 0.3mg injections of Bupe previously, that a 4mg dose of Suboxone would be more than sufficient for you, once a day. Always start at lower doses, because if you need more, you can always just take more. But if a person starts at a really high dose, then they'll never know of they could have been okay to function at a lower dose. Um - yeah - the Naloxone is added to the Suboxone to discourage or guard against Intravenous usage. The Naloxone is not orally activated and thus, in my book anyway, makes Subutex and Suboxone essentially the same drugs. Now - many other people don't think the same thing as me with respect to this aspect of these medications, so I would advise reading as much as you can about how people interpret the differences between these two drugs and if there is an effect that the Naloxone has. The Naloxone doesn't have any affect on the Bupe itself - as far as this question that you asked. It's actually the Bupe itself that does the blocking of other opiates or the forced withdrawal if other opiates are present when the Suboxone is taken. Alright - so these are my opinions. Take them for what they are worth. Good luck to you guys.
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#105420 - 03/31/06 10:27 AM
Re: Buprenorphine - Temgesic
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Stranger
Registered: 10/23/02
Posts: 3
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Hi All, I'm looking at doing a suboxone treatment program to get off hydro, and was just quoted $2400.00 from one doctor's office for a month long tapering program (and they're "not set up" to take insurance, ie, they're simply cashing in  ). I am going to call a few more, there is quite a list of doctors now (43 in my state). The thing is, I may be more a candidate for maintenance rather than getting off completely, as I still have the chronic pain issue, which is why hydro became an issue in the first place. Is temgesic suitable for chronic pain management? Also, if I do find a doctor covered by my insurance, will the insurance pay for the tabs? If not, do any of the offshore pharmacies carry it? I saw some NROP asking 500 bucks for 100 of the .2 tabs. Geesh. Probably cheaper on the street. Thanks, Freeone
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#105421 - 03/31/06 11:06 AM
Re: Buprenorphine - Temgesic
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GRAND Pooh-Bah
Registered: 10/27/03
Posts: 2169
Loc: Bearing Strait Ice/Land Bridge
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Freeone - Some good questions there and I'll try to take a stab at them, but I don't know how helpful I can be due to the whole nature of the Suboxone treatment. First of all - yeah, welcome to the world of Suboxone detox/treatment - where many doctors vary in the method they treat with, and differ in the price they charge. You'll find that. What you'll also find though is that there are a number of good doctors who will treat the condition, rather than doing what they have to to get your money. Meaning that they will be open or committed to doing a maitainence program or something longer than a month, and many also will take insurance - but this also depends on whether your insurance will cover the treatment. That's a whole other pickle to get into. As for your other questions...first let me say there is a difference between Temgesic and Suboxone/Subutex. Temgesic is Buprenorphine in 0.2mg doses and 0.3mg doses. It is found internationally and because of the low-dosage of medicine, usually is meant for patients who are not opiate-tolerant. Suboxone and Subutex are medicines, U.S.-made, which contain Buprenorphine, but in much higher doses, coming in 2mg and 8mg tablets. So - usually, if not always, you won't find any IOP's selling/offering Suboxone or Subutex. There are some who offer Temgesic tablets and there are email sources who sometimes offer Temgesic and Suboxone - but not at any price cheaper than at a pharmacy. Is Suboxone/Subutex suitable for chronic pain management? It depends on the person. Believe it or not, some doctors actually prescribe Suboxone/Subutex on an off-label basis for pain management. I've talked to a number of people who use these medications for pain management, rather than using other opiate-based painkillers. And these people who are getting it for pain management - they don't need to go to one of the licensed doctors for Suboxone, because any physician who has the ability to prescribe CIII drugs, can prescribe Sub on an off-label basis - meaning for anything not "detox" or "substance abuse." Lastly - like I said above, some insurance companies will cover the treatment, most all will cover the cost of the medicine if it is being used to treat pain, off-label. I have seen some companies though, after a while of paying the wicked-high price for the Sub tablets, tell their customers that they will no longer pay any Suboxone claims and that the patient must switch to a different drug, and most offer that Talwin would be an alternative. So those are some items that may help you decide about this. Be vigilent in finding a doctor who your comfortable with and who isn't going to rape you with cost. And remember that the published 'list' of certified doctors changes pretty much daily, although the list doesn't get updated that often, so if you run out of choices, simply start going through the phone-book and calling doctor's offices or psychiatrists' offices and asking them if they are able to treat with Suboxone/Subutex.
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#105423 - 09/14/06 03:19 PM
Re: Buprenorphine - Temgesic
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Banned: posts indicate abuse
Registered: 06/02/06
Posts: 383
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Hi all, I am about to use subutex to stop taking hydro. I am at about 15 max per day easily. I can take 3 at a time and no problem. I got a few 8mg subutex and plan to start tommorow with 2mg when WD's kick in. I went onto that heroind-opied detox message board, and while people there are great, they are totally telling me not to go on subutex for "only a 15 a day pill habit", let me tell you, I have gone CT and tapered and it SUCKED! I want something to take away the WD's and I have spoken to tons of people who used it for either long term or short term and none have said anything negative, all the responses were positive. I have like 10 hydro left and figure now is the time to use the sub and get through the 1st 4 days when WD is worst (at least for me) and then deal with being slugish but at least not in WD's. I want to use it for maintenece as I can get it again, and can also get hydro again. I just see it as a cure for the WD's. Not getting sick or feeling like [censored], all I hear is how great it is, no high but kills the WD's and even perks you up. So I plan to start low, like 2mg when I feel the wd's kick in. Does my plan sound like it will work ? I want to stay on the subutex only for a few days to get me through the worst of the hydro WD, I hear if you only use it short term, than you will experience no WD's from it, even then, I can taper down but I can't get a hydro refill for another 2 weeks and no way I want to deal with WD's AGAIN. I am thinking I found the perfect solution but on that message board, they make me think like I will regret ever taking subutex. I'm going for it as too many people have said how good it is. If I am wrong, I'll deal with it and update ya all! Wish me luck!
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