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#159792 - 04/09/05 07:11 PM what is the STRONGEST painkiller on the market today? ****
poppyale Offline
Enthusiast


Registered: 06/15/04
Posts: 280
Loc: united states of america
OK THERE ARE A LOT OF SCHEDULE 2 PAINKILLERS ON THE MARKET TODAY!!!! sorry i did not mean to yell!!!

anyway my question is what is the STRONGEST painkiller there is on the market today????

If anyone has any suggestions or if there is a doctor or a pharmasist in the house,please give me some info here!!

Personally I think that I would have to choose dilaudid(HYDROMORPHONE) or the other one i do not know the brand name but generic name is (OXYMORPHONE)

POPPYALE
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#159793 - 04/09/05 08:08 PM Re: what is the STRONGEST painkiller on the market today?
JethroBodine Offline
Board Addict


Registered: 06/20/03
Posts: 333
Loc: Ozark Mountains
Winchester 3" 12ga #4
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#159794 - 04/09/05 08:11 PM Re: what is the STRONGEST painkiller on the market today?
PlyrLacy Offline
Threadhead


Registered: 12/29/01
Posts: 941
Loc: Mid-Atlantic, USA
hahaha ... Amen!
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#159795 - 04/09/05 10:06 PM Re: what is the STRONGEST painkiller on the market today?
prettyday Offline
GRAND Pooh-Bah


Registered: 02/09/03
Posts: 1860
Loc: Coastal Sage Scrub
I'll second that motion!
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#159796 - 04/09/05 11:48 PM Re: what is the STRONGEST painkiller on the market today?
ksee Offline
Newbie


Registered: 04/05/05
Posts: 31
Loc: midwest usa
I really thought that oxycontin was the stongest pain killer besides demerol. Dilaudid is a couple levels down. I have tried both and in my opinion and from also what i've read i find this to be true. Anyone else agree??
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#159797 - 04/10/05 05:00 AM Re: what is the STRONGEST painkiller on the market today?
hibbs Offline

Threadhead


Registered: 08/22/03
Posts: 807
Loc: Up A Creek
Quote:

Winchester 3" 12ga #4



MAG of course!!

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#159798 - 04/11/05 07:59 AM Re: what is the STRONGEST painkiller on the market today?
HoneyWhite Offline
Stranger


Registered: 03/15/05
Posts: 22
Loc: Southern California, USA
Quote:

I really thought that oxycontin was the stongest pain killer besides demerol. Dilaudid is a couple levels down. I have tried both and in my opinion and from also what i've read i find this to be true. Anyone else agree??



Oxycontin gives me a rrreally bad headache. I'll second on the Demerol though.
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#159799 - 04/14/05 03:34 PM Re: what is the STRONGEST painkiller on the market today?
brblake Offline
Member


Registered: 01/18/05
Posts: 111
I think its oxcycotin also but give realy bad headachs.
but gits rid of pain good.
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#159800 - 04/14/05 07:41 PM Re: what is the STRONGEST painkiller on the market today?
leelee27 Offline
Old Hand


Registered: 04/06/05
Posts: 438
Loc: B.F.E.
I hear that oxy's are strong but I myself have never tried anything over a 10mg percocet so I am not real sure
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#159801 - 04/14/05 10:15 PM Re: what is the STRONGEST painkiller on the market today?
prettyday Offline
GRAND Pooh-Bah


Registered: 02/09/03
Posts: 1860
Loc: Coastal Sage Scrub
I kept getting Demerol for my migraines for a very short Pill-induced migraine side effect to try to eliminate my ovarian cysts...Demerol turned out to make my tongue swell up and and all sorts of allergies...actually turned out quite dangerous...yet Demerol was THE THING according to E/Rs....now I see in articles in Time magazine that quite a few people reacted as I did, and Demerol is on its way out...so...I say again....what is the answer....probably anything I/V, right? Because they say that oral meds are consumed less? But then if people get used to getting relief in an I/V fashion rather than the other methods...that is a short road to problems....is there really a single answer to this question?
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#159802 - 04/15/05 08:31 AM Re: what is the STRONGEST painkiller on the market today?
ele123 Offline
Veteran


Registered: 09/20/03
Posts: 518
Check out the post I started called "Narcotic Converter". It will give you nearly exact strength comparisons.

http://www.drugbuyers.com/freeboard/showflat.php/Cat/0/Number/242073/an/0/page/1#242073
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#159803 - 05/01/05 12:57 PM Re: what is the STRONGEST painkiller on the market today?
Se7endthree Offline
Stranger


Registered: 04/25/05
Posts: 12
Fentanyl - hands down
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#159804 - 05/01/05 01:20 PM Re: what is the STRONGEST painkiller on the market today?
Benton Offline
Banned. Multiple ID's. Soliciting


Registered: 01/21/05
Posts: 300
Loc: Florida
I agree on the Fentanyl. I have been on just about everything over the passed 14 years and am now on Fentanyl Patches and they do give consistant strong pain relief. But it also comes in different forms for different effect. I use the Actiq pops for quick Extreme pain.

But a shot of Fentanyl in the ER is the strongest next to IV. This is my opinion so remember everyrone has different preferrences.

B
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#159805 - 05/01/05 02:01 PM Re: what is the STRONGEST painkiller on the market today?
deakins1 Offline
Stranger


Registered: 04/23/05
Posts: 7
I have a question about the patches: I could not keep them on when they got wet plus I was darn tired the entire time. I know my doc would put me back on them (that is what he wants me to have) but I was just exhausted the entire six weeks.

He told me that there was something he could give me-a stimulate-to offset the sleepy effect but I don't want to take more-I was looking for less.

How do you keep from falling asleep driving (if you do) and work? How do you keep it on -I had to tape it? And what do you do when it is not enough? My PM doc does not "believe" in "breakthrough" pain-
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#159806 - 05/01/05 03:26 PM Re: what is the STRONGEST painkiller on the market today?
Benton Offline
Banned. Multiple ID's. Soliciting


Registered: 01/21/05
Posts: 300
Loc: Florida
If you call the phone number on the box, they will send you the Bioclusive covers that help keep the patches on longer. Also, talk to your doctor about prescibing them every two days instead of three.

That helped me a lot with those problems.

As far as them making me sleepy, I didn't have that problem. I did have it when I was using Methadone. I couldn't even stay awake on Methadone. I do drink a lot of coffee which I am sure makes a difference.

Did your doctor say what he would give you to offset the tiredness?

B
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#159807 - 05/01/05 03:42 PM Re: what is the STRONGEST painkiller on the market today?
CARLITOS_WAY Offline
Threadhead


Registered: 06/27/04
Posts: 789
Loc: WASHINGTON, USA
Did I miss something while I was sleeping. I thought methadone could only be used for narcotic addiction, with very strict Rules...but then again I still haven't woken up from the early 70's.
_________________________
If I had kept all the 2 cents worth I gave away, I would be wealthy in $$$

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#159808 - 05/01/05 03:46 PM Re: what is the STRONGEST painkiller on the market today?
Benton Offline
Banned. Multiple ID's. Soliciting


Registered: 01/21/05
Posts: 300
Loc: Florida
No No No...lol

Methadone is a wonderful Pain Management tool! It is very inexpensive and works great. It was a pain killer long before it was used for addiction. It just happens to help with addiction as well.

When I would get my prescriptions my doctor would write FOR PAIN MANAGEMENT ONLY on the top for my benefit because of the stigma attached to it.

B.
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#159809 - 05/01/05 06:01 PM Re: what is the STRONGEST painkiller on the market today?
Arielle Offline
Member


Registered: 01/25/05
Posts: 113
Quote:

Winchester 3" 12ga #4



I agree with this completely, the way I have been feeling lately. Pain-wise that is....
Arielle
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#159810 - 05/02/05 02:38 AM Re: what is the STRONGEST painkiller on the market today?
drbob Offline
Member


Registered: 12/07/02
Posts: 189
Loc: okla. city
I think #1 IV Dilaudid #2 IV demerol #3methadone. I have not tried the fentanyl patches so they could easily be one of the top 3.
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#159811 - 05/02/05 02:44 AM Re: what is the STRONGEST painkiller on the market today?
Poetking05 Offline
Stranger


Registered: 01/17/05
Posts: 14
1. Demerol

2. Methadone

3. Fentanyl

4. And in a very distant fourth...Dilaudid


I'll graduate medical school in a few months...my opinion from what I've seen and experienced myself.
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#159812 - 05/02/05 05:22 AM Re: what is the STRONGEST painkiller on the market today?
NFR Offline
Board Addict


Registered: 12/24/04
Posts: 309
Loc: U.S NorthWest
Iam not a sure ,however I read somewhere that fentanyl is many times more potent then all other forms of opiate based pain killers. If anyone has any input or wants to disput that ,please do ,I remember reading something about the potency of fentanyl , and how very strong it was ,however it was a long time ago and things surely do change with time !

Edited by NFR (05/02/05 05:23 AM)
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#159813 - 05/02/05 10:10 PM Re: what is the STRONGEST painkiller on the market today?
tvstar23 Offline
Newbie


Registered: 04/13/05
Posts: 49
Loc: Left Coast
The last time I was in the hospital (a few weeks ago), I was on a dilaudid pump, which worked very well, and seemed very strong. I've also had a lot of IV demerol, and though it seems stronger to me, the effects wore off quicker. Also, oddly enough, IV Fentanyl worked really well, but the patch didn't do anything for me AND it made my feet swell up to giant balloon size. Has anyone else ever had their feet swell on Fentanyl? It was weird, and not fun.

Take it easy everyone,
TV
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#159814 - 05/02/05 11:43 PM Re: what is the STRONGEST painkiller on the market today?
Templar90 Offline
Member


Registered: 04/06/05
Posts: 100
The debate about strength is often clouded by the amount of relief achieved by individual patients. This can also depend on delivery and condition. But when it comes to milligram for milligram (or microgram as the case may be) opiates are measured against IV morphine, as it is not synthetic. The PDR comes down this way (administered IV)....

1. Fentanyl. Hands down the most potent opiate to be synthesized. It is measured in micrograms, and is approx 100 times stronger than morphine.

2. Hydromorphone (Dilaudid)

3. Levorphanol (rarely used)

4. Morphine
tie
Methadone

5. Meperidine (Demerol)

6. Oxycodone

7. Hydrocodone

8. Codeine

9. Propoxyphene (Darvocet)


These are the big ones. On a personal note, I use 300McG/hr of Fentanyl in the form of 3 100McG Duragesic patches and Dilaudid 8mg tablets for breakthrough pain. These are pretty high doses, but I'm a big guy (6'6", 230), and have a pretty messed up back courtesy of a big rig than turned my Tahoe (and my spine) into scrap. I switched to the patches from 320mg of Oxycontin so I could have better long term relief.

Trivia: The absolute strongest opioid produced is called Sublimaze. It is an ultra-potent form of fentanyl that is 1000 times stronger than Morphine, and is used during anesthesia and to sedate large mammals, such as rhinos and elephants.
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#159815 - 05/02/05 11:47 PM Re: what is the STRONGEST painkiller on the market today?
Templar90 Offline
Member


Registered: 04/06/05
Posts: 100
TVstar - I too have occasional issues with my feet swelling. Also, it took about 48 hours to get the full relief of the Duragesic patches. Also, they don't last the full 72 hours as advertised, so my MD prescribes them q48-72. My insurance does not cover their cost, so I end up paying about $75-100/day for pain relief.
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#159816 - 05/03/05 12:27 AM Re: what is the STRONGEST painkiller on the market today?
Stfarmasist Offline
Member


Registered: 04/29/05
Posts: 130
Loc: WEST
I TAKE 70 MG OF LIQUID METHADONE DAILY FOR CHRONIC BACK PAIN IT WORKS PRETTY GOOD BLOWS HYDRO CAN PERCOCET OUT OF THE WATER ON PAIN RELIEF BECAUSE METHADONE HAS A HALF LIFE 24 HOURS PAIN FREE, BUT CAN LAST UP TO 48 HOURS, TO PEOPLE ADDICTED TO HYDRO AND OXY OR DEPENDENT ON THEM, CONSIDER METHADONE AS AN OPTION, YOUR NOT HIGH AS A KITE ALL THE TIME BUT IT TAKES CARE OF THE PAIN EFFIENTLY AND ALOT BETTER FOR YOUR BODY THAN THY LORTAB AND OXY WITH ALL THAT TYLENOL ALSO IT IS A LOT CHEAPER!!!! METHADONE HAD SAVED MY LIFE, I WAS GOING ER TO ER, I WAS EVEN SUCIIADL AT A POINT, I SPENT 6 MONTHS ON THE STREETS BUT SINCE METHADONE HAVE GOTTEN MY LIFE BACK , IT REALLY HAS DONE WONDERS FOR ME I ASK ANYONE WITH A BAD HYDRO/OXY DEPENDDANCY TO CONSIDER METHADONE
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#159817 - 05/25/05 08:40 AM Re: what is the STRONGEST painkiller on the market today?
Painguy Offline
Stranger


Registered: 05/04/04
Posts: 4
Loc: Canada
Being in Canada, we have several different formulations that I don't read about here.

For my Chronic back pain I went from Tylenol 3's, to Tylenol 4's until my tolerance built up so that I was getting toxic on the Tylenol. (300 tabs a month)

When I was moved to Codeine Contin - a time relase Codeine-only tablet, at 200mg x 3 per day it solved the problem and I was able to get active again. However, after a year at the maximum dosage, I started to get swelling and fluid retention and my phosphate levels were way to high. My Doc finally moved me to HydroMorph Contin (Purdue) which is a sustained relase Dilaudid supplied in a gelatin capsule full of hard beads of medicine which can actually be opened and poured on your food (swallow, don't chew!). I don't know if this is consistent with the medication that I have seen described here, but I am glad to not have to deal with patches - I hated them when I quit smoking years ago. These capsules come in 3, 6, 12, 18, 24 and 32 mg. I have never been more pain free in years, although I did go through some significant codeine withdrawal since the 12 hours advertised as effective dosage intervals is actually only about 8 hours with me. My dosage has been adjusted several times to 3 times a day, I have 8mg Dilaudids for breakthrough pain, and I am now doing great. (fingers crossed)!

Morphine gives me headaches, and I have never had luck with Oxy-anything, I must not have those receptors. Codeine was more effective than Percocet (Oxy Co-set in Canada) I have never tried Fetanyl or Methadone, but Demerol, Talwin, Buprenorphine and Darvon (propox) are partial antagonists and all send me into some withdrawal and have limited analgesia. All of the most effective that seem to be described here all seem to be pure opiod agonists. Would anyone agree?
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#159818 - 05/25/05 08:50 PM Re: what is the STRONGEST painkiller on the market today?
Opie_Yates Offline
Veteran


Registered: 08/11/03
Posts: 712
Loc: Out the Doghouse's Back Door
Palladone seems to be the big thing now. In it's therapeutic dose, dilaudid would seem to be the winner based on my experience with the board. I'm not impressed with Oxycontin 40's, as I still have to take quite a bit of hydro during the day...even from the get go.
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********YES! DEFINITELY VOTE IN '08!********

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#159819 - 06/09/05 02:21 PM Re: what is the STRONGEST painkiller on the market today?
gatorade Offline
Board Addict


Registered: 07/17/03
Posts: 315
Loc: US
Hands down IV Levo Dromoran (levorphanol) with IV fentanyl in a close 2nd. As far as oral medications, I find that either dilaudid or Oxyfast are far superior to any other meds.
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#159820 - 06/09/05 03:12 PM Re: what is the STRONGEST painkiller on the market today?
ele123 Offline
Veteran


Registered: 09/20/03
Posts: 518
Quote:

Fentanyl. Hands down the most potent opiate to be synthesized



I am pretty sure the Fentanyls are the strongest pain killers in use. There are other opiates even stronger than the Fentanyls (hundreds of times stronger), but they are never used. I think Prodine is one, but I may be getting my opiates confused.

I think levorphanol is only 5 times stronger than morphine, where as Fentanyl is 50 to 100 times stronger than morphine (depending on which Fentanyl).

Maybe someone who is a chemist or pharmacologist knows?

Also, here is a neat narcotic converter:

http://www.globalrph.com/narcotic.cgi
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#159821 - 06/09/05 03:27 PM Re: what is the STRONGEST painkiller on the market today?
Sweetz Offline
Diamond Mind
GRAND Pooh-Bah